Gibtulio Met 12.5mg/500mg Tablet 10

Lupin Ltd

Strip of 10 Units

Read Info

MRP ~~₹125~~

₹106.25

₹12.5/Units

15% off

*MRP inclusive of all taxes

Get it By

Change

100% genuine medicines

Safe & secure payments

15 days Easy returns

Prescription required for this medicine

Store Below 30^o C

Composition

Empagliflozin (12.5 Mg) + Metformin (500 Mg)

Gibtulio Met 12.5mg/500mg Tablet is primarily used for managing type 2 diabetes mellitus in adults. This combination medicine is part of the sodium-glucose co-transporter-2 (SGLT2) inhibitors and biguanide antidiabetic classes of medicines.

In addition to this key use, this medicine also helps control high blood sugar levels, preventing complications related to diabetes. It further aids in reducing the risk of cardiovascular events such as heart attack and stroke in patients with established cardiovascular disease and type 2 diabetes.

You should take this medicine as directed by your doctor. Before starting, it's important to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medication, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Customers also bought

Homochek Capsule 10

MRP~~₹128.5~~

₹106.66

17% OFF

Save 50.1% with Substitute

Shelcal Xt Tablet 15

MRP~~₹429~~

₹343.2

20% OFF

Save 50.1% with Substitute

Evion 400 Capsule 20

MRP~~₹86.87~~

₹74.71

14% OFF

Ketocip Soap 75gm

MRP~~₹145.2~~

₹72.45

50% OFF

Dynapar Qps Plus Solution 30ml

MRP~~₹361.7~~

₹289.36

20% OFF

Gelusil Mps Original Mint Flavour Sugar Free Liquid 400ml

MRP~~₹254.06~~

₹205.79

19% OFF

Save 50.1% with Substitute

Calcimax Forte+ Tablet 30

MRP~~₹313~~

₹250.4

20% OFF

Folvite Tablet 45

MRP~~₹76.1~~

₹64.15

16% OFF

Save 50.1% with Substitute

Crocin Advance Tablet 20

MRP~~₹20.16~~

₹17.56

13% OFF

Save 29.33% with Substitute

Supradyn Immuno + Tablet 30

MRP~~₹295~~

₹230.1

22% OFF

Himalaya Gentle Baby Shampoo 100ml

MRP~~₹115~~

₹105.8

8% OFF

Gelusil Mps Mint Flavour Sugar Free Liquid 200ml

MRP~~₹168.28~~

₹139.67

17% OFF

Save 50.1% with Substitute

One Touch Verio Test Strips 50

MRP~~₹1245~~

₹1120.5

10% OFF

Walcobal Forte Tablet 10

MRP~~₹270~~

₹134.73

50% OFF

Gelusil Mps Original Mint Flavour Chewable Tablet 15

MRP~~₹26.39~~

₹21.11

20% OFF

Volini Pain Relief Spray 15gm

MRP~~₹83~~

₹64.74

22% OFF

Save 50.53% with Substitute

Bio D3 Plus Capsule 15

MRP~~₹331~~

₹269.76

19% OFF

Save 50.1% with Substitute

Calciquick Ccd Tablet 40

MRP~~₹485~~

₹242.01

50% OFF

Ra Thermoseal Rapid Action Fresh Mint Gel 100 GM

MRP~~₹151.25~~

₹136.12

10% OFF

Jusgo Spray 75gm

MRP~~₹268.95~~

₹223.23

17% OFF

Save 41.55% with Substitute

Gibtulio Met 12.5mg/500mg Tablet is used for the following:

Management of type 2 diabetes mellitus in adults
Assisting diet and exercise in controlling high blood sugar levels
Reduction of the risk of cardiovascular events such as heart attack and stroke in patients with type 2 diabetes and established cardiovascular disease
Use in patients already being treated with empagliflozin and metformin as separate tablets

Here's how to take Gibtulio Met 12.5mg/500mg Tablet:

Swallow the tablet whole with a glass of water.
Do not crush, cut or chew the tablet.
If you forget a dose, take it as soon as you remember unless it's nearly time for your next dose, in which case skip the missed dose and continue your regular schedule.

Gibtulio Met 12.5mg/500mg Tablet is taken orally.

Gibtulio Met 12.5mg/500mg Tablet may have the following common side effects:

Upper respiratory tract infections
Urinary tract infections
Genital mycotic infections: These are yeast or fungal infections that can occur in the genital area.
Nausea
Vomiting
Diarrhoea
Increased urination

Managing the Side Effects:

Most side effects are temporary and generally harmless, and they resolve when you discontinue using Gibtulio Met 12.5mg/500mg Tablet. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor.

Here are some guidelines for managing common side effects:

Diarrhoea: Try taking Gibtulio Met 12.5mg/500mg Tablet with food to lessen this effect.
Increased urination: If this is disturbing your sleep, consider taking your tablet in the morning rather than at night.

Gibtulio Met 12.5mg/500mg Tablet contains two active components:

Empagliflozin (12.5 mg): This component works by inhibiting a substance in your kidneys known as SGLT2. By doing so, it reduces the reabsorption of glucose and increases its excretion through urine, helping to lower your blood sugar levels.
Metformin (500 mg): As a biguanide antidiabetic agent, metformin works by decreasing glucose production in your liver. It also reduces the intestinal absorption of glucose and increases its utilisation in your body by improving insulin sensitivity.

Pregnancy

Gibtulio Met 12.5mg/500mg Tablet is not recommended during pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.

Breastfeeding

This medicine is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol during the course of Gibtulio Met 12.5mg/500mg Tablet. Consult with your doctor for specific advice.

Liver

This medicine is often prescribed for adults, who may be more susceptible to liver health issues. Discuss liver-related concerns with your doctor before starting treatment with Gibtulio Met 12.5mg/500mg Tablet.

Kidney

Gibtulio Met 12.5mg/500mg Tablet should not be used in patients with severe kidney disease or issues. Consult your doctor if you have a history of kidney problems.

Using Machines & Driving

There's no known effect of this medicine on your ability to drive or operate machinery. However, if you experience any side effects that might affect your ability, consult your doctor.

Allergy

Gibtulio Met 12.5mg/500mg Tablet is contraindicated in patients with hypersensitivity to its active ingredients, empagliflozin and metformin. If you're allergic to these, it's best to avoid this medication.

Children

This medicine is not recommended for use in children under 18 years of age unless specifically prescribed by a doctor.

Older Patients

Older patients should take Gibtulio Met 12.5mg/500mg Tablet under medical supervision as they may be more susceptible to its side effects. Older patients might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Gibtulio Met 12.5mg/500mg Tablet interacts with the following medicines:

NSAIDs: Medicines like ibuprofen and naproxen can impair renal function, which may increase the risk of lactic acidosis when you take them with this medicine.
Cationic Medicines: Medications such as amiloride, digoxin, morphine, and ranitidine that are eliminated by renal tubular secretion can interact with metformin and increase the risk of lactic acidosis.
Diuretics: Loop diuretics like furosemide and torsemide may decrease renal function and increase the risk of lactic acidosis.
Insulin or Insulin Secretagogues: Taking medications like insulin and glipizide with Gibtulio Met 12.5mg/500mg Tablet can increase your risk of hypoglycaemia.

Drug-Food Interactions

Certain foods can interact with Gibtulio Met 12.5mg/500mg Tablet.

Drug-Disease Interactions

Gibtulio Met 12.5mg/500mg Tablet interacts with the following diseases:

Renal Disease: If you have severe renal impairment or end-stage renal disease, taking this medicine could exacerbate your condition.
Liver Disease: If you have liver problems, extra caution is needed since liver disease might affect how the medicine works in your body.
Heart Failure: This medication should be used carefully if you have heart failure as it can impact the effectiveness of the medicine.
Genital Mycotic Infections: If you have a history of genital mycotic infections or urinary tract infections, taking this medicine could cause these conditions to flare up.

Daily Dose

The daily dose of Gibtulio Met 12.5mg/500mg Tablet should be taken as advised by your doctor. The exact dosage may vary based on individual factors like the severity of your diabetes and how well you respond to the medication. Always stick to the prescribed dosage and avoid exceeding it without first consulting your doctor.

Over Dose

If you accidentally take more than your prescribed dose of Gibtulio Met 12.5mg/500mg Tablet, you might feel nauseous or have diarrhoea. Don't panic, but do let your doctor know about this.

Missed Dose

If you forget to take a dose of Gibtulio Met 12.5mg/500mg Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your usual dosing schedule. Never double up on doses without discussing it with your doctor.

Securely store Gibtulio Met 12.5mg/500mg Tablet in a dry, cool place, ideally at room temperature below 30°C.
Keep it away from direct sunlight and extreme heat or cold.
Ensure the Tablet container is tightly closed when not in use to prevent exposure to air and moisture.
Always keep this medication out of reach of children.
Do remember to use Gibtulio Met 12.5mg/500mg Tablet before its expiry date.

Since Gibtulio Met 12.5mg/500mg Tablet is taken to manage type 2 diabetes, you should limit your intake of foods high in sugar and processed carbs. Opt for whole grains, fruits, vegetables, and lean proteins instead.
Regular physical activity is key in managing type 2 diabetes. Try to incorporate at least 30 minutes of moderate exercise, like walking or cycling, into your daily routine.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus, Cardiovascular Disease
Drug Category	SGLT2 Inhibitor, Biguanide
Therapeutic Category	Antidiabetic

What is Gibtulio Met 12.5mg/500mg Tablet used for?

This medicine is used to manage type 2 diabetes in adults, especially when diabetes isn't adequately controlled by metformin alone or with other antidiabetic medicines.

How does Gibtulio Met 12.5mg/500mg Tablet work?

It contains two ingredients, empagliflozin and metformin, that work together to lower blood sugar levels by reducing glucose production and increasing glucose excretion.

How should I take this medicine?

You must take the medicine as directed by your doctor.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember unless it's almost time for the next dose. In this case, skip the missed dose.

Who shouldn't take Gibtulio Met 12.5mg/500mg Tablet?

It shouldn't be taken by people with severe kidney problems, metabolic acidosis, or those allergic to empagliflozin, metformin, or any components of the tablet.

Are there any precautions I should take while using this medicine?

Stay hydrated and limit alcohol intake to reduce lactic acidosis risk. Consult your doctor if you experience symptoms like malaise, myalgias, or abdominal pain.

Can Gibtulio Met 12.5mg/500mg Tablet interact with other medicines?

Yes, it may interact with certain medications like NSAIDs or diuretics. Always inform your doctor about all medicines you're taking before starting this medication.

Last Updated On 13 May. 2025 | 10:30AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: GERMANY

Expiry on or after: November 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Clinics Cardive Publishing (Pty) Ltd. (2022, October 1). FDA approves empagliflozin for heart failure regardless of ejection fraction. PubMed Central (PMC). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9887434/
Empagliflozin: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a614043.html
Empagliflozin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09038
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Metformin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696005.html

Was this product description useful?

16 people find this information helpful

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

Recommended Substitute

50.1% CHEAPER

Empagligen M 12.5/500 Tablet 10

Tablets India Ltd

Strip of 10 Units

₹62.38

₹6.24/Units

100 + users bought this instead

Quick links

Uses
Directions for Use
Route of Administration
Side Effects
Medicine Activity
Precautions & Warnings
Interactions
Dosage
Storage
Diet & Lifestyle
Fact Box
FAQs

More Products By Lupin Ltd

Lupical D3 Capsule 4

MRP~~₹100.8~~

₹50.3

50% OFF

Ondero 5mg Tablet 10

MRP~~₹174.9~~

₹148.67

15% OFF

Save 50.1% with Substitute

Ivabrad 5 Tablet 15

MRP~~₹494.85~~

₹395.88

20% OFF

Save 50.1% with Substitute

Clopitab Tablet 15

MRP~~₹113.7~~

₹90.96

20% OFF

Save 50.1% with Substitute

Clopitab A 75 Capsule 15

MRP~~₹133.25~~

₹106.6

20% OFF

Save 55.87% with Substitute

Beplex Forte Tablet 20

MRP~~₹56.85~~

₹45.48

20% OFF

Gluconorm Sr 500 Tablet 15

MRP~~₹33.9~~

₹27.12

20% OFF

Save 50.1% with Substitute

Tonact 10 Tablet 15

MRP~~₹82.95~~

₹66.36

20% OFF

Save 50.1% with Substitute

Gluconorm G2 Tablet 15

MRP~~₹348.9~~

₹279.12

20% OFF

Save 50.1% with Substitute

Isolazine Tablet 15

MRP~~₹230.55~~

₹184.44

20% OFF

Save 50.1% with Substitute

Gluconorm G1 Tablet 15

MRP~~₹225.3~~

₹180.24

20% OFF

Save 50.1% with Substitute

Ondero Met 2.5mg/500mg Tablet 10

MRP~~₹143~~

₹121.55

15% OFF

Save 50.1% with Substitute

Rablet D Capsule 15

MRP~~₹317~~

₹263.11

17% OFF

Save 50.1% with Substitute

Planep Tablet 15

MRP~~₹483.75~~

₹387

20% OFF

Save 50.1% with Substitute

Tonact Asp 75 Capsule 15

MRP~~₹57.05~~

₹45.64

20% OFF

Save 50.1% with Substitute

Starpress Xl 50 Tablet 15

MRP~~₹98.1~~

₹78.48

20% OFF

Save 50.1% with Substitute

Faa 20 Tablet 15

MRP~~₹304.3~~

₹252.57

17% OFF

Fruselac Tablet 10

MRP~~₹61.85~~

₹49.48

20% OFF

Starpress Xl 25 Tablet 15

MRP~~₹71.4~~

₹57.12

20% OFF

Save 50.1% with Substitute

Timzid Mr Tablet 15

MRP~~₹152.9~~

₹122.32

20% OFF

Save 50.1% with Substitute

Top-Selling Health Essentials

Prohance D Diabetes Care Chocolate Flavour Powder 400gm

MRP~~₹862~~

₹818.9

5% OFF

Ensure Diabetes Care Chocolate Flavour Refill Powder 200gm

MRP~~₹540~~

₹518.4

4% OFF

Fresubin Dm Cardamom Flavour Powder 400gm

MRP~~₹1054~~

₹948.6

10% OFF

Era Dn Capsule 10

MRP~~₹240.8~~

₹199.86

17% OFF

Ensure Diabetes Care Vanilla Delight Flavour Zero Added Sucrose Refill Powder 375gm

MRP~~₹925~~

₹878.75

5% OFF

Vidavance Chocolate Flavour Powder Jar 200gm

MRP~~₹540~~

₹486

10% OFF

Health Articles

View All

Aesthetic & Skin Care

Dark Circles: Causes, Types, And Home Remedies

Lifestyle Management

Top 10 Health Benefits of Drinking Fennel (Saunf) Water

Food & Nutrition

Black Seed Oil: Health Benefits and Side Effects

Aesthetic & Skin Care

The 8 Best Under Eye Creams for Dark Circles

Aesthetic & Skin Care

17 Simple Home Remedies For Fungal Infections

Product Reviews

Best Stretch Mark Removal Creams and Oils to Try in 2025

Aesthetic & Skin Care

10 Benefits of Aloe Vera for Face and Skin

Disorder & Deficiency

10 Best Medicines for Instant Constipation Relief in India

Health Conditions In Hindi

फेफड़ों में जमा बलगम निकालने और साफ करने के असरदार तरीके

Health Conditions In Hindi

वजन बढ़ाने के लिए क्या खाएं? जानें (High Calorie Foods in Hindi)

Food & Nutrition

Jungle Jalebi Fruit: Uses, Benefits And Side Effects

Diabetes

Is Apple Good for Diabetes? Benefits & Best Ways to Eat It

Related Products

Company

About Us Health Article Health Stories Diseases & Health Conditions Ayurveda All Medicines All Brands Need Help FAQ

Social

Legal

Terms & Conditions Privacy Policy Editorial Policy Returns & Cancellations

Claim your complimentary health and fitness tips subscription and stay updated on our newest promotions.

Registered Office Address

Intellihealth Solutions Private Limited

Office Unit no. 1, 2, 5, & 7, 6th floor Urmi Corporate Park Solaris, Saki Vihar Rd, Opp. L&T Flyover, New Mhada Colony, Budhia Jadhav Wadi, Mumbai, Maharashtra 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

Grievance Officer

Name: Chandrasekhar Swaminathan

Email: grievance-officer@truemeds.in

Download Truemeds

Manage your health with ease Download Truemeds today!Get easy access to medicine refills, health information, and more. With our app, you'll never have to wait in line again. Download now and start taking control of your health.