Divalpro 125 MG Tablet 10

Zydus Cadila

Strip of 10 Units

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MRP ~~₹41~~

₹32.8

₹4.1/Units

20% off

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Prescription required for this medicine

Store Below 30^o C

Composition

Divalproex (125 Mg)

Strength:

250 MG 500 MG 125 MG

Valance 125 Tablet is primarily used for the treatment of manic episodes associated with bipolar disorder. This medicine is part of the anticonvulsant group of medications.

Apart from epilepsy, this medicine is also beneficial in managing seizures and in preventing migraine headaches.

The dosage and frequency of this medicine should be decided by your doctor, based on your age, weight, and the condition being treated. Before you start this medicine, it's important to let your doctor know about any existing health conditions or medications you're currently taking. If you notice any side effects, notify your doctor immediately. Be sure to take the medicine for the full duration prescribed by your doctor for optimal results.

Valance 125 Tablet is used for the following:

Managing different types of seizures, including complex partial seizures and absence seizures
Controlling manic episodes in individuals with bipolar disorder
Helping to prevent migraine headaches in adults

When it comes to taking Valance 125 Tablet, follow these steps:

Swallow the tablet whole with a bit of water.
Do not crush or chew the tablet.
Always stick to your doctor's instructions on how many tablets you should take.
Remember, it's important not to stop taking this medicine without consulting your doctor first.

Valance 125 Tablet is taken orally.

Valance 125 Tablet may have the following common side effects:

Nausea and vomiting
Abdominal pain
Dizziness and drowsiness
Tremors
Weakness
Hair loss
Weight gain
Blurred vision

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Valance 125 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and vomiting: Try taking Valance 125 Tablet with food or milk to lessen this effect.
Dizziness and drowsiness: Consider taking this medicine at bedtime if it causes you these symptoms during the day.

Valance 125 Tablet contains divalproex (125 mg). Here's how it works:

Increases GABA levels: Divalproex works by promoting the concentration of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, in your brain. Now, a neurotransmitter is a chemical messenger that transmits signals in the brain. GABA is an inhibitory neurotransmitter, meaning it reduces the activity of nerve cells in the brain.
Stabilises electrical activity: By increasing GABA levels, Divalproex helps to stabilise the electrical activity in your brain. This control over the electrical activity is what helps to manage seizures and regulate mood.

Pregnancy

Valance 125 Tablet is contraindicated during pregnancy as it may harm the developing fetus. If you are pregnant or planning to conceive, it’s crucial to inform your doctor before starting this medication. Alternative treatments may be recommended to ensure the safety of both mother and baby.

Breastfeeding

If you are breastfeeding, use Valance 125 Tablet with caution. The medication may pass into breast milk and affect the nursing infant. Consult your doctor to weigh the risks and benefits before using this medication while breastfeeding.

Alcohol

Avoid consuming alcohol while taking Valance 125 Tablet. Alcohol can increase the risk of side effects such as drowsiness and dizziness, and it may worsen the condition being treated.

Liver

Individuals with liver disease or significant liver dysfunction should not use Valance 125 Tablet, as it can exacerbate liver-related issues. If you have a history of liver problems, discuss this with your doctor to determine the best course of treatment.

Kidney

Patients with a history of kidney problems should exercise caution when taking Valance 125 Tablet. Your doctor will evaluate your kidney function and provide guidance on whether this medication is safe for you.

Using Machines & Driving

Valance 125 Tablet can cause dizziness and drowsiness, which may impair your ability to drive or operate heavy machinery. Avoid such activities if you experience these side effects.

Allergy

Do not take Valance 125 Tablet if you are allergic to divalproex sodium or any of its components. Seek immediate medical attention if you notice signs of an allergic reaction, such as rash, itching, or difficulty breathing.

Children

Caution is advised while giving Valance 125 Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Valance 125 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Valance 125 Tablet interacts with the following medicines:

Anticonvulsants: Valance 125 Tablet can interact with anticonvulsants like phenytoin, carbamazepine, and lamotrigine, affecting their blood levels and efficacy.
Antibiotics: Carbapenem antibiotics (Imipenem, Meropenem) could potentially interact with Valance 125 Tablet, impacting its effectiveness.
Salicylates: If you take aspirin or other salicylates while also taking Valance 125 Tablet, it could increase your risk of bleeding.

Drug-Disease Interactions

Valance 125 Tablet interacts with the following diseases:

Liver Disease: Patients with liver disease or significant liver dysfunction should not use this medication as it may worsen their condition.
Urea Cycle Disorders: Valance 125 is contraindicated in patients with known urea cycle disorders as it might intensify their condition.
Pancreatitis: This tablet should be used cautiously by individuals who have a history of pancreatitis as it might exacerbate their symptoms.

Daily Dose

Take the daily dose of Valance 125 Tablet as your doctor prescribes. This may vary depending on factors such as the severity of your condition and how well you respond to the medication. Always follow the prescribed dosage and never increase it without consulting your doctor.

Over Dose

In case of an overdose, common symptoms may include dizziness, heart block, and deep coma. Adhere to the prescribed dosage. If you have taken an excess dose than prescribed, inform your doctor.

Missed Dose

If you have missed taking Valance 125 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take an extra tablet to make up for a missed dose without consulting your doctor.

Store Valance 125 Tablet at room temperature not exceeding 30°C.
Keep it in a dry place away from direct sunlight and moisture.
Make sure to keep this medicine out of sight and reach of children.
Always check the expiry date on the package and use the medicine before this date.

For those managing epilepsy, try to maintain a consistent eating pattern. Skipping meals can trigger seizures for some individuals, so ensure you're having regular meals.
If you're taking Valance 125 Tablet for bipolar disorder, incorporating exercise into your routine can help manage mood swings. A simple walk or yoga session could prove beneficial. Always consult your doctor before starting any new exercise regimen.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Bipolar Disorder, Migraine Prevention
Drug Category	Anticonvulsant
Therapeutic Category	Mood stabiliser

What is Valance 125 Tablet used for?

This tablet is used to manage seizures, bipolar disorder, and it can also help prevent migraine headaches in adults.

How does Valance 125 Tablet work?

It works by increasing the concentration of a brain chemical called gamma-aminobutyric acid (GABA) which helps control seizures and regulate mood.

Are there any side effects of Valance 125 Tablet?

Common side effects include nausea, dizziness, hair loss, and weight gain. Serious side effects like pancreatitis or liver damage require immediate medical attention.

Can I take Valance 125 Tablet if I am pregnant?

Can I stop taking Valance 125 Tablet suddenly?

No, abrupt discontinuation may lead to withdrawal symptoms or worsening of your condition. Always consult your doctor before stopping the medicine.

What should I do if I forget to take a dose of Valance 125 Tablet?

If you miss a dose, take it as soon as you remember unless it's near the time for next dose. Do not double the dose.

Is it safe to drink alcohol while taking Valance 125 Tablet?

It's recommended to avoid alcohol while taking this medicine as it can increase the risk of side effects and worsen your condition.

Last Updated On 02 Aug. 2025 | 11:33AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 9 years

PhD in Chemistry

Reviewed by

Pragati Bhosale

Medical Content Reviewer | 2 years

M. Pharmacy

Check out Editorial Policy

Manufacturer details

5V74+4P2, Jay Prakash Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

Expiry on or after: December 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Depakote (divalproex sodium) Tablets for Oral use. This label may not be the latest approved by FDA. (n.d.). Fda.Gov. Retrieved November 29, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
DailyMed. (n.d.). Divalproex Sodium - Divalproex Sodium Tablet, Delayed Release. Retrieved April 1, 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=1ec1a441-218a-4c80-a0cb-69bcc327f472&version=22
U.S. Food and Drug Administration. (2015). Approval letter - Stavzor. Retrieved April 1, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2015/203730Orig1s000ltr.pdf
Davis, L. L., Bartolucci, A., & Petty, F. (2005). Divalproex in the treatment of bipolar depression: A placebo-controlled study. Journal of Affective Disorders, 85(3), 259–266. Retrieved 15 October 2024, from
https://pubmed.ncbi.nlm.nih.gov/15780695/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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