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CompositionCyblex M 60 XR Tablet is used for managing type 2 diabetes in adults. It is combination of extended-release Gliclazide (sulfonylurea) and Metformin (biguanide). It helps regulate blood sugar levels and is beneficial for those whose diabetes cannot be controlled by metformin alone, playing a crucial role in comprehensive diabetes management.
Cyblex M 60 XR Tablet is used for managing Type 2 Diabetes in adults. It is prescribed for improving blood sugar levels when diet and exercise alone are insufficient. It enhances the body's response to naturally produced insulin and works to lower the amount of glucose produced by the liver, assisting with glycemic control in patients where diabetes cannot be controlled by Metformin alone.
Here's how you should take Cyblex M 60 XR Tablet:
Follow the dosage and timing instructions provided by your doctor precisely.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.
Cyblex M 60 XR Tablet is taken orally.
Cyblex M 60 XR Tablet may cause diarrhoea, nausea, vomiting, abdominal pain, loss of appetite, hypoglycaemia (low blood sugar), and taste disturbances. Speak with your doctor if these side effects continue.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Cyblex M 60 XR Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Cyblex M 60 XR Tablet with food to lessen this effect.
Hypoglycaemia: If you experience low blood sugar, consume glucose-containing products like a small sugar bar or sugary drink.
Cyblex M 60 XR Tablet contains two active ingredients:
Gliclazide (60 mg): This ingredient belongs to the sulfonylurea class of medicines. It works by binding to the sulfonylurea receptors on pancreatic beta cells. This action closes specific potassium channels and opens calcium channels within these cells. The result is an increased release of insulin from the pancreas, helping to lower blood sugar levels.
Metformin (500 mg): As a biguanide medication, metformin primarily works by reducing the amount of glucose produced by your liver. Additionally, it helps improve your body's natural response to insulin, ensuring that more glucose is taken up and used by your body's cells. Unlike some other diabetes medications, metformin doesn't tend to cause low blood sugar (hypoglycaemia) or excessively high insulin levels.
Cyblex M 60 XR Tablet is not recommended during pregnancy. If you are pregnant or planning to conceive, consult your doctor before taking this medicine.
Breastfeeding mothers should exercise caution while using Cyblex M 60 XR Tablet. It is advisable to discuss with your doctor before starting this medicine.
Alcohol intake should be avoided while taking Cyblex M 60 XR Tablet as it enhances the hypoglycemic effect of gliclazide and increases the risk of lactic acidosis with metformin.
If you have liver issues, caution is advised when using Cyblex M 60 XR Tablet. This medicine may affect liver function, so discuss your liver health with your doctor before starting this medication.
It's important to exercise caution before using Cyblex M 60 XR Tablet if you have a history of kidney problems. Discuss any renal health concerns with your doctor before starting this medication.
There is no specific data available related to the use of machinery or driving while on this medication. It's best to observe how you react to the medicine, and consult your doctor for any concerns.
If you are allergic to gliclazide, metformin or any other component of Cyblex M 60 XR Tablet, refrain from using this medicine. Discuss any known allergies with your doctor beforehand.
Children under 18 years should not be given Cyblex M 60 XR Tablet without medical supervision. Always consult your doctor before administering any medicine to a child.
Older patients may take Cyblex M 60 XR Tablet under medical supervision as they might be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Discuss any health concerns with your doctor before starting this medication.
Cyblex M 60 XR Tablet interacts with the following medicines:
Anticoagulants: Gliclazide in Cyblex M 60 XR Tablet can increase the effects of blood-thinning medicines like warfarin and heparin.
Beta-blockers: Medicines such as propranolol and atenolol may alter the way Cyblex M 60 XR Tablet works, potentially affecting blood sugar control.
Cyblex M 60 XR Tablet has no known specific interactions with foods. However, maintaining a balanced diet is vital for managing diabetes effectively.
Cyblex M 60 XR Tablet interacts with the following diseases:
Kidney disease: Patients with renal dysfunction should use this medicine with caution, due to the risk of lactic acidosis from metformin.
Liver disease: This medicine should be used cautiously by patients with hepatic impairment, as altered liver function can impact the effectiveness of this medicine.
Your doctor will prescribe the daily dose of Cyblex M 60 XR Tablet based on your individual condition and response to treatment. Always follow the prescribed dosage and refrain from changing it without consulting your doctor.
An overdose of Cyblex M 60 XR Tablet may lead to common side effects like stomach upset or diarrhoea. If you suspect an overdose, inform your doctor who will guide you on the necessary steps.
If you forget to take a dose of Cyblex M 60 XR Tablet, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed one and resume your regular schedule. Avoid increasing your dosage without consulting your doctor.
Store Cyblex M 60 XR Tablet in a cool, dry place, ideally between 10°C to 25°C.
Keep it away from excessive heat and direct sunlight.
Ensure the medicine is always out of reach of children.
Always check the expiry date on the label and use the medicine before it.
Engage in moderate exercise regularly as it can help improve your body's insulin sensitivity and manage your blood sugar levels.
Opt for a balanced diet rich in fibre and low in refined carbs and sugars to help control your blood glucose levels. Be sure to consult your doctor about a diet plan that would work best for you.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Sulfonylurea, Biguanide |
| Therapeutic Category | Oral Anti-Diabetic |
This medicine helps manage type 2 diabetes by reducing blood sugar levels. It combines the actions of gliclazide and metformin for improved control.
Gliclazide in the tablet stimulates insulin production from the pancreas, while metformin reduces glucose production by the liver, enhancing body's response to insulin.
If you miss a dose, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one.
Yes, this medicine can be used alongside other diabetes medicines, but always consult your doctor first as hypoglycaemia risk may be higher.
Common side effects include gastrointestinal disturbances and hypoglycaemia. If you experience these or any unusual symptoms, consult your doctor immediately.
Avoid alcohol intake and monitor renal function regularly. Also, exercise caution if you are elderly or have adrenal or pituitary insufficiency.
Store them in a cool, dry place, ideally between 10°C to 25°C. Keep them out of reach of children and within the expiry date.
Check out Editorial Policy
Panacea Biotec Limited. (2019). PRODUCT MONOGRAPH GLIZID-M gliclazide 80mg and Metformin 500mg. https://media.panaceabiotec.com/documents/2019/7/27/ProductMonograph-GlizidM-GliclazideplusMetformin.pdf
Gliclazide: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01120
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
Polavarapu, N. K., Kale, R., Sethi, B., Sahay, R. K., Phadke, U., Ramakrishnan, S., Mane, A., Mehta, S., & Shah, S. (2020). Effect of Gliclazide or Gliclazide plus Metformin Combination on Glycemic Control in Patients with T2DM in India: A Real-World, Retrospective, Longitudinal, Observational Study from Electronic Medical Records. Drugs - Real World Outcomes, 7(4), 271–279. https://doi.org/10.1007/s40801-020-00206-7
Alsharidah, M., Algeffari, M., Abdel-Moneim, A. H., Lutfi, M. F., & Alshelowi, H. (2018). Effect of combined gliclazide/metformin treatment on oxidative stress, lipid profile, and hepatorenal functions in type 2 diabetic patients. Saudi Pharmaceutical Journal, 26(1), 1–6. https://doi.org/10.1016/j.jsps.2017.11.007
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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