Apizirex 2.5 Tablet 10 is an anticoagulant medicine (blood thinner) used to treat and prevent blood clots in the veins and heart. It helps lower the risk of stroke in people with an irregular heart rhythm (non-valvular atrial fibrillation) and prevents blood clots in the legs and lungs. It is also used to prevent clots following hip or knee replacement surgery.
It contains apixaban, a factor Xa inhibitor that reduces the blood's ability to form harmful clots. Take it exactly as prescribed by your doctor, with or without food. Do not skip doses or stop taking it suddenly without medical advice, as doing so significantly increases the risk of blood clots or stroke.
Care should be taken to prevent injuries and cuts while taking blood thinners. Use a soft toothbrush, take care when handling sharp objects, and carry a medical alert card stating that you are taking an anticoagulant medicine.
Before starting treatment, tell your doctor if you have any bleeding disorders, liver or kidney disease, stomach ulcers, or recent surgical procedures. Inform your doctor or dentist before undergoing any medical or dental procedures, as the medicine may need to be temporarily paused. It is not recommended during pregnancy or breastfeeding. Report any unusual or prolonged bleeding immediately.
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Apizirex 2.5 Tablet 10
Strip of 10 Units
MRP ₹175
₹87.5
₹8.75/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Apizirex 2.5 Tablet 10
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Uses of Apizirex 2.5 Tablet 10
Apizirex 2.5 Tablet 10 is used in adults to prevent and treat blood clots in various cardiovascular and post-surgical conditions.
Uses of Apizirex 2.5 Tablet 10 are:
- Stroke Prevention: Reduces the risk of stroke and systemic blood clots in adults with non-valvular atrial fibrillation.
- Blood Clot Treatment: Treats blood clots in the deep veins of the legs (deep vein thrombosis) and lungs (pulmonary embolism).
- Recurrence Prevention: Prevents blood clots from reforming in the legs and lungs following initial treatment.
- Post-Surgical Clot Prevention: Prevents blood clot formation after knee or hip replacement surgery.
Directions for Use of Apizirex 2.5 Tablet 10
Here are some straightforward steps to follow while taking Apizirex 2.5 Tablet 10:
Swallow the tablet whole with water.
Do not crush or chew the tablet.
The medicine can be taken with or without food.
Always take your dose at approximately 12-hour intervals, such as morning and evening.
Keep taking this medicine regularly as prescribed by your doctor.
Never alter your dose or stop taking Apizirex 2.5 Tablet 10 without consulting your doctor.
Route of Administration
Apizirex 2.5 Tablet 10 is taken orally.
Side Effects of Apizirex 2.5 Tablet 10
Apizirex 2.5 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Apizirex 2.5 Tablet 10:
- Bleeding: Increased risk of bleeding, including easy bruising, nosebleeds, bleeding gums, or prolonged bleeding from cuts.
- Nervous System: Severe headache, dizziness, or fainting.
- Digestive: Feeling sick (nausea).
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolves on discontinuing the use of Apizirex 2.5 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Nausea: Try taking Apizirex 2.5 Tablet 10 with food or milk.
Dizziness and fainting: If this occurs, sit or lie down to prevent falls.
How Apizirex 2.5 Tablet 10 Works?
Apizirex 2.5 Tablet 10 contains Apixaban (2.5 mg), which acts on the body in the following ways:
Inhibits factor Xa: Apixaban works by selectively blocking an enzyme called Factor Xa in your body. This enzyme plays a key role in forming blood clots.
Prevents fibrin formation: By blocking Factor Xa, apixaban effectively prevents the conversion of fibrinogen (a protein available in your blood) into fibrin, another protein that's integral for blood clot formation.
Maintains essential clotting: Despite this anticoagulant activity, apixaban still allows your body to form clots necessary to stop bleeding from injuries. This is particularly important as it ensures that while harmful clots are prevented, essential clotting is maintained.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Apizirex 2.5 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
If you are breastfeeding, it's recommended to discuss with your doctor before starting Apizirex 2.5 Tablet 10.
Alcohol
Consuming alcohol while on Apizirex 2.5 Tablet 10 may increase the risk of bleeding. Always discuss your alcohol consumption with your doctor.
Liver
If you have liver problems, discuss them with your doctor before starting Apizirex 2.5 Tablet 10. This medicine may affect liver function.
Kidney
Caution is advised before using Apizirex 2.5 Tablet 10 if you have a history of any kidney problems. It is a good idea to consult your doctor before taking this medicine.
Use In Driving And Operating Machinery
Apizirex 2.5 Tablet 10 may cause dizziness or fainting in some individuals. Avoid operating machinery, driving, or any activities requiring mental alertness until you know how this medicine affects you.
Allergy
Do not take this medicine if you have an allergy to apixaban or any other components of Apizirex 2.5 Tablet 10.
Children
Apizirex 2.5 Tablet 10 is meant for adult use only. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Apizirex 2.5 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Interactions of Apizirex 2.5 Tablet 10
Drug-Drug Interactions
Apizirex 2.5 Tablet 10 Interacts with the Following Medicines:
Blood thinners: Medicines like aspirin or clopidogrel may interact with Apizirex 2.5 Tablet 10, potentially increasing the risk of bleeding.
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken with Apizirex 2.5 Tablet 10, NSAIDs such as ibuprofen can elevate chances of bleeding.
Antifungals: Medicines like ketoconazole or itraconazole can raise apixaban levels in your body, possibly enhancing the risk of bleeding.
Antidepressants: Certain medications such as fluoxetine or fluvoxamine can increase apixaban levels in the body.
Drug-Food Interactions
Apizirex 2.5 Tablet 10 has no known specific food interactions and can be taken with or without food.
Drug-Disease Interactions
Apizirex 2.5 Tablet 10 Interacts with the Following Diseases:
Liver disease: People with liver disease should use Apizirex 2.5 Tablet 10 cautiously as it could exacerbate their condition.
Kidney disease: Patients with kidney problems need to be careful while taking this medication as it may increase the risk of bleeding.
Bleeding disorders: People suffering from conditions that increase bleeding should avoid this medicine.
Dosage of Apizirex 2.5 Tablet 10
Daily Dose
Your doctor will prescribe the appropriate daily dose of Apizirex 2.5 Tablet 10, taking into consideration factors such as your health condition and how you respond to the medicine. Always take Apizirex 2.5 Tablet 10 exactly as your doctor has advised. Never alter the dose on your own.
Over Dose
Taking more than the prescribed dose of Apizirex 2.5 Tablet 10 can increase your risk of side effects like excessive bruising and frequent nosebleeds. If you suspect an overdose, inform your doctor without delay.
Missed Dose
If you forget to take a dose of Apizirex 2.5 Tablet 10, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take extra medicine to make up for a missed dose; always consult your doctor if you need advice on managing missed doses.
Storage
Keep Apizirex 2.5 Tablet 10 in its original packaging to protect it from light and moisture.
Store it at room temperature, ideally below 30°C.
Ensure the storage area is dry and not exposed to high heat.
Always keep this medicine out of reach of children.
Remember to use Apizirex 2.5 Tablet 10 before the expiry date mentioned on the pack.
Special Dietary And Lifestyle Recommendation
If you have atrial fibrillation, maintain a balanced diet low in saturated fats and high in fibre to help manage your condition alongside taking Apizirex 2.5 Tablet 10.
After hip or knee replacement surgery, regular gentle exercises under your doctor's guidance can aid recovery and decrease the risk of deep vein thrombosis. Always consult your doctor before starting any new exercise routine.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism |
| Drug Category | Factor Xa Inhibitor |
| Therapeutic Category | Anticoagulant |
Frequently Asked Questions (FAQs)
What is Apizirex 2.5 Tablet 10 used for?
Apizirex 2.5 Tablet 10 is primarily used to prevent formation of harmful blood clots in patients with irregular heart rhythm and post-surgery patients.
How does the medicine work?
Its active ingredient, apixaban, inhibits a clotting factor called Factor Xa, preventing the formation of blood clots while still allowing necessary clotting.
How should I take Apizirex 2.5 Tablet 10?
The medicine is taken orally, swallowed whole with water. You can take it with or without food, but always follow your doctor's advice.
What are the common side effects of this medicine?
Common side effects include nausea, easy bruising, and minor prolonged bleeding like nosebleeds or from cuts. Contact your doctor if you experience these.
Can anyone take Apizirex 2.5 Tablet 10?
No, people with severe liver disease, active pathological bleeding, or allergy to apixaban should avoid taking this medicine. Consult your doctor first.
Does it interact with other medicines?
Yes, it may interact with medicines that affect blood clotting and some antidepressants, antifungals and HIV medications. Always inform your doctor about all medicines you're taking.
What should I do in case of an overdose?
Overdose can increase the risk of serious bleeding. If suspected, seek immediate medical help, presenting symptoms can include excessive bruising or nosebleeds.
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Manufacturer details
Country of origin: INDIA
References
Bristol-Myers Squibb. (2012). ELIQUIS prescribing information [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202155s000lbl.pdf
Apixaban: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06605
DailyMed - APIXABAN tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=095a08ac-cf0e-497e-a682-ddef38d6b29c
APIXabAN: MedlinePlus Drug Information. (n.d.). https://medlineplus.gov/druginfo/meds/a613032.html
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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