Nitrobact-100 Tablet contains Nitrofurantoin, a specialized antibiotic used primarily to treat and prevent bacterial urinary tract infections (UTIs). Unlike broad-spectrum antibiotics, it specifically targets the bacteria commonly found in the urinary system. It works by entering the bacterial cell and damaging its genetic material, which stops the infection from spreading and allows the body to clear the bacteria.
For the best results, it is often recommended to take this medication with food or milk to enhance absorption and reduce stomach upset. It is critical to complete the entire course of treatment, even if the burning or urgency disappears quickly, to ensure the infection does not return. This medication may turn your urine a dark yellow or brown color, which is a harmless and temporary side effect of the treatment.
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Nitrobact 100 Capsule 10
Strip of 10 Units
MRP ₹92.28
₹73.82
₹9.23/Units
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CompositionAbout Nitrobact 100 Capsule 10
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Uses of Nitrobact 100 Capsule 10
Nitrobact-100 Capsule is used to treat simple bacterial urinary tract infections (UTIs), including bladder (cystitis). It can also be taken long-term to prevent recurrent UTIs in adults, helping maintain urinary tract health.
Directions for Use of Nitrobact 100 Capsule 10
To use Nitrobact-100 Capsule correctly:
- Swallow the capsule whole with a glass of water.
- Do not crush or chew the capsule.
- Always follow the dosage instructions given by your doctor.
- The medicine should be taken with food to improve absorption and minimise gastrointestinal side effects.
- Consult your doctor for personalised advice on how to take this medication.
Route of Administration
Nitrobact-100 Capsule is taken orally.
Side Effects of Nitrobact 100 Capsule 10
Nitrobact-100 Capsule may cause side effects like nausea, vomiting, diarrhoea, flatulence, headache, and dizziness. If any of these side effects persist or worsen, consult your doctor.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Nitrobact-100 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Ensuring that you take Nitrobact-100 Capsule with food will reduce the risk of side effects, especially nausea and vomiting. Stay hydrated by drinking plenty of fluids during the day to manage other common side effects.
How Nitrobact 100 Capsule 10 Works?
Nitrobact-100 Capsule contains nitrofurantoin (100 mg), which acts on the body through these mechanisms:
- Bacterial DNA Disruption: Nitrofurantoin interferes with bacterial DNA production. DNA is vital for bacteria to reproduce and spread, so by disrupting its production, nitrofurantoin effectively inhibits bacterial growth.
- Targeted Action: Nitrofurantoin particularly targets common bacteria causing urinary tract infections. By acting on these specific bacteria, nitrofurantoin helps in managing urinary tract infections effectively.
Safety Measures & Warnings
Pregnancy
Nitrobact-100 Capsule is contraindicated in pregnant patients at term. It is best to consult your doctor before taking this medicine if you are pregnant.
Breastfeeding
Trace amounts of the medicine may pass into breast milk and result in anaemia in infants. If you are breastfeeding, it is recommended that you discuss your situation with your doctor before starting Nitrobact-100 Capsule.
Alcohol
There's no known interaction between Nitrobact-100 Capsule and alcohol. However, since it may increase the risk of side effects, it's always a good idea to avoid alcohol consumption while on antibiotics. Consult your doctor about any possible risks.
Liver
Nitrobact-100 Capsule should be taken with caution if you have liver issues. Make sure to discuss these concerns with your doctor before starting this medicine.
Kidney
This medicine should be used with caution if you have kidney health problems. As always, consulting your doctor before starting Nitrobact-100 Capsule would be advisable.
Use In Driving And Operating Machinery
Nitrobact-100 Capsule may make you feel dizzy or unwell. Avoid driving or using machines until you're feeling better.
Allergy
It is contraindicated in those patients with known hypersensitivity to nitrofurantoin. If you've previously had an allergic reaction to nitrofurantoin, using Nitrobact-100 Capsule may not be advisable. Always inform your doctor of any allergies before starting a new medicine.
Children
Children under 12 years should not take Nitrobact-100 Capsule unless specifically advised by a doctor. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Nitrobact-100 Capsule under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.
Interactions of Nitrobact 100 Capsule 10
Drug-Drug Interactions
Nitrobact-100 Capsule interacts with the following medicines:
- Antacids: Medicines containing magnesium trisilicate can hamper the absorption of nitrofurantoin in your body. Specific examples are Gaviscon and Digene.
- Oral Contraceptives: Nitrobact-100 Capsule may decrease the effectiveness of birth control pills such as I-pill and Unwanted-72.
- Urine Alkalinizers: Medicines that make your urine less acidic, like potassium citrate, can increase the risk of nitrofurantoin toxicity in your body.
Drug-Food Interactions
Nitrobact-100 Capsule has interactions with certain food items:
- Dairy Products: Food rich in calcium like cheese and yogurt might interfere with nitrofurantoin absorption.
Drug-Disease Interactions
Nitrobact-100 Capsule interacts with the following diseases:
- Renal Impairment: If you have severe kidney disease (creatinine clearance < 60 mL/min), this medicine is not advised as it might worsen your condition.
- Anaemia: Nitrobact-100 Capsule could potentially exacerbate symptoms in patients with low blood cell counts.
- Diabetes: This medicine could affect blood sugar control, hence regular monitoring of glucose levels is necessary.
Dosage of Nitrobact 100 Capsule 10
Daily Dose
The daily dose of Nitrobact-100 Capsule should be taken as directed by your doctor. This dosage might vary based on factors such as the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never exceed it without consulting your doctor.
Over Dose
In case of an overdose of Nitrobact-100 Capsule, you might experience overdose symptoms like vomiting. If this persists, inform your doctor.
Missed Dose
If a regular dose of Nitrobact-100 Capsule is missed, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.
Storage
- Store Nitrobact-100 Capsule in a dry place to protect it from moisture.
- Keep the temperature steady, not going above 30°C.
- Shield the medicine from direct light to maintain its effectiveness.
- Always keep Nitrobact-100 Capsule out of reach of children.
- Make sure you use the medicine before its expiry date for optimal benefits.
Special Dietary And Lifestyle Recommendation
- Consuming plenty of fluids, especially water, can help manage urinary tract infections by flushing out bacteria. So, make it a point to stay well-hydrated throughout the day.
- As a dietary measure, consider including vitamin C-rich foods like oranges, lemons, and strawberries in your diet. Vitamin C makes urine more acidic, which inhibits the growth of bacteria contributing to urinary tract infections.
Fact Box
| Dosage Forms Available | Capsule |
| Habit Forming | No |
| Ailment | Urinary Tract Infections, Cystitis, Kidney Infections |
| Drug Category | Bacterial DNA Disruptor |
| Therapeutic Category | Antibiotic |
Frequently Asked Questions (FAQs)
What is Nitrobact-100 Capsule used for?
Nitrobact-100 Capsule is primarily used to manage bacterial infections of the urinary tract, such as cystitis and kidney infections.
How does Nitrobact-100 Capsule work?
Nitrofurantoin in Nitrobact-100 Capsule kills bacteria causing urinary tract infections by disrupting their DNA production, thus inhibiting their multiplication.
How should I take Nitrobact-100 Capsule?
You should swallow the Nitrobact-100 Capsule whole with food or milk. Do not crush or chew the capsule. Follow your doctor's instructions.
What are the side effects of Nitrobact-100 Capsule?
Common side effects include nausea, vomiting, diarrhoea, headache, and dizziness. If you notice any unusual symptoms, consult your doctor immediately.
Can I take Nitrobact-100 Capsule while pregnant?
Nitrobact-100 Capsule is not recommended during late pregnancy (38-42 weeks) due to the risk of haemolytic anaemia in the newborn. Always consult your doctor.
Are there any precautions while using Nitrobact-100 Capsule?
Precautions are necessary if you have anaemia, diabetes or gastrointestinal disorders. Consult your doctor before starting this medication.
How should I store Nitrobact-100 Capsule?
Store Nitrobact-100 Capsule in a dry place at a temperature not exceeding 30°C and protect it from light. Keep it out of children's reach.
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Manufacturer details
Country of origin: INDIA
References
- Asis Pharmaceuticals. (2021). Nitrofurantoin 100mg Capsules. Electronic Medicines Compendium (EMC). Retrieved 1 April 2024, from https://www.medicines.org.uk/emc/files/pil.13236.pdf
- FDA. (2021). Macrodantin® (Nitrofurantoin Capsules, USP). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/016620Orig1s076lbl.pdf
- Huttner, A., Verhaegh, E. M., Harbarth, S., Muller, A. E., Theuretzbacher, U., & Mouton, J. W. (2015). Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials. Journal of Antimicrobial Chemotherapy, 70(9), 2456-2464. https://doi.org/10.1093/jac/dkv147
- MedlinePlus. (2021). Nitrofurantoin. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682291.html
- Meiji Pharma Spain. (2021). Nitrofurantoin 100mg Capsules. Health Products Regulatory Authority (HPRA). Retrieved 1 April 2024, from https://www.hpra.ie/img/uploaded/swedocuments/3a92db31-ada9-46ed-abc6-f4c67161c564.pdf
- Squadrito, F. J., & del Portal, D. (2021). Nitrofurantoin. In StatPearls [Internet]. Retrieved 1 April 2024, from https://www.ncbi.nlm.nih.gov/books/NBK470526/
- Tripathi, K. D. (2019). Essentials of medical pharmacology (8th ed.). Jaypee Brothers Medical Publishers (P) Ltd.
- Cimolai, N., & Cimolai, T. (2007). Nitrofurantoin and pregnancy. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 176(13), 1860–1861. https://doi.org/10.1503/cmaj.1070028
- Zao, J., Koren, G., & Bozzo, P. (2014). Using nitrofurantoin while breastfeeding a newborn. Canadian family physician Medecin de famille canadien, 60(6), 539–540.
- Mergenhagen, K. A., Wattengel, B. A., Skelly, M. K., Clark, C. M., & Russo, T. A. (2020). Fact versus Fiction: a Review of the Evidence behind Alcohol and Antibiotic Interactions. Antimicrobial agents and chemotherapy, 64(3), e02167-19. https://doi.org/10.1128/AAC.02167-19
- Luk, T., Edwards, B. D., Bates, D., Evernden, C., & Edwards, J. (2021). Nitrofurantoin-induced liver failure: A fatal yet forgotten complication. Canadian family physician Medecin de famille canadien, 67(5), 342–344. https://doi.org/10.46747/cfp.6705342
- Singh, N., Gandhi, S., McArthur, E., Moist, L., Jain, A. K., Liu, A. R., Sood, M. M., & Garg, A. X. (2015). Kidney function and the use of nitrofurantoin to treat urinary tract infections in older women. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 187(9), 648–656. https://doi.org/10.1503/cmaj.150067
- Bhatt, C., Doleeb, Z., Bapat, P., & Pagnoux, C. (2023). Drug-induced haemolysis: another reason to be cautious with nitrofurantoin. BMJ case reports, 16(1), e251119. https://doi.org/10.1136/bcr-2022-251119
- White, W. T., Harrison, L., & Dumas, J., 2nd (1984). Nitrofurantoin unmasking peripheral neuropathy in a type 2 diabetic patient. Archives of internal medicine, 144(4), 821.
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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