Zyle 100 Tablet 10

Leeford Healthcare

Strip of 10 Units

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MRP ~~₹21.15~~

₹11.36

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Composition

Allopurinol (100 Mg)

Strength:

300 MG 100 MG

Zyle 100 Tablet 10 is used to manage gout, a type of arthritis that causes painful inflammation in some joints. This medicine falls under the category of xanthine oxidase inhibitors.

This tablet is also prescribed to control high uric acid levels that can occur as a result of certain cancer treatments. It also serves in preventing the recurrence of kidney stones in individuals who have elevated uric acid levels in their urine.

Before starting the medicine, it's recommended you consult your doctor to determine the appropriate dosage and frequency. It's crucial you inform your doctor about any pre-existing conditions or ongoing medications before commencing this medicine. If you experience any side effects while taking this medication, notify your doctor immediately. Also, continue taking the tablet for the duration prescribed by your doctor for optimal results.

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Zyle 100 Tablet 10 is used for the following:

Managing gout, a form of arthritis causing severe joint pain and redness.
Lowering uric acid levels in the blood, associated with certain cancer treatments.
Preventing kidney stones in individuals with high uric acid levels in their urine.

Swallow the tablet whole with a glass of water.
It's best to take the tablet after a meal to minimise stomach upset.
If you have any questions about using Zyle 100 Tablet 10, consult your doctor.

Zyle 100 Tablet 10 is taken orally.

Zyle 100 Tablet 10 may cause the following common side effects:

Nausea and vomiting
Diarrhoea
Drowsiness
Skin rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zyle 100 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips for managing common side effects:

Nausea and vomiting: Try to take Zyle 100 Tablet 10 with a meal to lessen this effect.
Diarrhoea: Consider taking this medicine in the evening to lessen daytime discomfort.

Zyle 100 Tablet 10 contains allopurinol (100 mg), which acts on your body as follows:

Xanthine Oxidase Inhibition: Allopurinol restricts an enzyme called xanthine oxidase in your body. This enzyme is responsible for producing uric acid.
Reduction of Uric Acid: By inhibiting xanthine oxidase, allopurinol effectively reduces the production of uric acid, thereby lowering its levels in your blood and reducing the risk of gout attacks and uric acid-related kidney stones.

Pregnancy

If you're pregnant, it's important to exercise caution when taking Zyle 100 Tablet 10, as it may cause foetal harm. It's best to consult your doctor before using this medication.

Breastfeeding

Due to the potential risk of serious adverse reactions in a breastfed child, it is suggested that women avoid breastfeeding while undergoing treatment with Zyle 100 Tablet 10. Please consult your doctor for the best advice.

Alcohol

Drinking alcohol should be limited or avoided while taking Zyle 100 Tablet 10, as it can increase uric acid levels and trigger gout attacks. Consult your doctor about safe levels of alcohol consumption.

Liver

Be careful while using Zyle 100 Tablet 10 in case of liver health issues. It's advised to discuss your liver health with your doctor before starting the medicine.

Kidney

It's recommended to consult your doctor about your kidney health before starting Zyle 100 Tablet 10, as it is prescribed for treating kidney stone-related conditions.

Using Machines & Driving

Zyle 100 Tablet 10 may cause drowsiness. Exercise caution when driving or operating machinery after taking this medicine. Consult your doctor before use.

Allergy

Allergic reactions to allopurinol may occur. If you are aware of any allergies, consult your doctor before starting Zyle 100 Tablet 10.

Children

In some cases, Zyle 100 Tablet 10 is given to paediatric patients with leukemia, lymphoma, and solid tumor malignancies who are receiving cancer therapy that causes elevated serum and urinary uric acid levels.

Older Patients

Older patients should take Zyle 100 Tablet 10 under medical supervision, as they may be more susceptible to its effects. Caution is advised if patients are above 70 years of age. Consulting your doctor beforehand is a wise step.

Drug-Drug Interactions

Zyle 100 Tablet 10 interacts with the following medicines:

Antibiotics: Medicines including ampicillin and amoxicillin may interact with Zyle 100 Tablet 10, potentially increasing the risk of rash.
Chemotherapy Medicines: Specific medications such as cyclophosphamide and mercaptopurine might interact with Zyle 100 Tablet 10, leading to increased side effects or reduced effectiveness.
Diuretics: Thiazide diuretics like hydrochlorothiazide can interact with Zyle 100 Tablet 10, possibly leading to increased uric acid levels.
Blood Thinners: When taken with Zyle 100 Tablet 10, warfarin could have its effectiveness affected.

Drug-Food Interactions

None

Drug-Disease Interactions

Zyle 100 Tablet 10 interacts with the following diseases:

Liver Disease: People with liver disease should exercise caution as Zyle 100 Tablet 10 could exacerbate their condition.
Kidney Disease: Patients with kidney disease might need dose adjustments when using Zyle 100 Tablet 10 due to decreased kidney function.
Diabetes: Blood sugar levels could be affected when you're on this medication.
Heart Failure: Individuals suffering from heart failure are advised to exercise caution while using Zyle 100 Tablet 10 due to potential fluid retention.
Asymptomatic Hyperuricemia: Zyle 100 Tablet 10 is not recommended for individuals treated for asymptomatic hyperuricemia.

Daily Dose

Your daily recommended dose of Zyle 100 Tablet 10 should be taken as your doctor prescribes. This dosage may change depending on the severity of your symptoms and how you respond to the medicine. Always follow your doctor's instructions, and don't increase your dosage without consulting them.

Over Dose

In case you take more Zyle 100 Tablet 10 than your doctor has prescribed, you may feel nauseous, start vomiting, experience diarrhoea, or feel drowsy. If these symptoms persist, please consult your doctor.

Missed Dose

If you forget to take your dose of Zyle 100 Tablet 10, try to take it as soon as you remember. However, if it's nearly time for the next dose, leave out the one you missed and continue with your regular dosage schedule. Never increase your dosage without consulting with your doctor.

Store Zyle 100 Tablet 10 in a cool, dry place, ideally at room temperature, around 25°C.
Keep it away from direct light and moisture.
Always ensure the medicine is out of reach of children.
Use Zyle 100 Tablet 10 before its expiry date.

Try limiting foods that are a rich source of proteins, as this can help prevent gout attacks.
Stay well-hydrated by drinking at least 2-3 litres of water every day. This helps to prevent the formation of kidney stones linked with high uric acid levels.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gout, High Uric Acid
Drug Category	Xanthine Oxidase Inhibitor
Therapeutic Category	Antigout Agent

How long does it take for Zyle 100 Tablet 10 to start working?

It may take several weeks to months for full effects. Initially, gout attacks may increase, but these will subside over time. Consult your doctor for individualized directions and advice.

Can I drink alcohol while taking Zyle 100 Tablet 10?

Avoid or limit alcohol, as it can increase uric acid levels and trigger gout attacks. If you regularly drink alcohol, please consult your doctor.

What should I do if I miss a dose of Zyle 100 Tablet 10?

Take the missed dose as soon as you remember. If it's nearly time for the next one, skip the missed dose and continue your regular schedule. Never adjust your dosage without consulting your doctor.

Can Zyle 100 Tablet 10 cure gout?

While Zyle 100 Tablet 10 helps manage gout by reducing uric acid levels, it doesn't cure the condition. Healthy lifestyle changes are also necessary. It is a good idea to consult your doctor before taking this medicine.

Can I stop taking Zyle 100 Tablet 10 if I feel better?

No, continue taking this medicine even if you feel well. Abruptly stopping it may worsen your gout symptoms. Please consult your doctor for guidance.

Can pregnant or breastfeeding women take Zyle 100 Tablet 10?

Pregnant and breastfeeding women should consult their doctor before taking this medication due to uncertain safety data in these populations.

What precautions should I take when using Zyle 100 Tablet 10?

Consult with your doctor about any pre-existing medical conditions like liver disease, diabetes, high blood pressure, heart failure, or thyroid disorders before using this medicine.

Last Updated On 13 May. 2025 | 11:17AM (IST)

Certified Content

Written by

Dr. Pauravi Abad

Medical Content Writer | 5 years

MBBS

Reviewed by

Dr. Divya Chauhan

Medical Content Writer & Reviewer | 7 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

Leo House, Shaheed Bhagat Singh Nagar, Dugri Dhandra Road, Near Joseph School Ludhiana PB 141002 IN

Country of origin: INDIA

Expiry on or after: December 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. National Library of Medicine. (2024, April 1). Allopurinol: MedlinePlus Drug Information. MedlinePlus. https://medlineplus.gov/druginfo/meds/a682673.html
U.S. Food and Drug Administration. (2024, April 1). Label: Allopurinol- allopurinol tablet. AccessData. https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/018832s056s058s061,018877s063s065s068lbl.pdf
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 135401907, Allopurinol. Retrieved June 18, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Allopurinol.
Allopurinol: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00437
Qurie, A., Preuss, C. V., & Musa, R. (2023, June 26). Allopurinol. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK499942/

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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