Valkem-OD 500 Tablet is used primarily to manage epilepsy (recurrent seizures). Containing Divalproex (anticonvulsant), it helps in the management of bipolar disorder (extreme mood swings) and in the prevention of migraines, which are recurring intense headaches often accompanied by nausea and sensitivity to light or sound.
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Valkem Od 500 Tablet 10
Strip of 10 UNITS
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MRP ₹223.1
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CompositionAbout Valkem Od 500 Tablet 10
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Uses of Valkem Od 500 Tablet 10
Valkem-OD 500 Tablet is used for managing various types of epilepsy, such as complex partial seizures and absence seizures. It is also effective in stabilising mood and reducing symptoms during manic episodes linked to bipolar disorder, and is used for the prevention of migraine headaches in adults.
Directions for Use of Valkem Od 500 Tablet 10
Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
You can take this medicine with or without food.
Always follow your doctor's advice regarding how to use this medicine.
Route of Administration
Valkem-OD 500 Tablet is taken orally.
Side Effects of Valkem Od 500 Tablet 10
Valkem-OD 500 Tablet may lead to the following side effects: nausea, vomiting, stomach pain, diarrhoea or constipation, dizziness, sleepiness, weakness, tiredness, tremors (involuntary shaking), hair loss, and weight gain.
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Valkem-OD 500 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:
Nausea or stomach pain: Try taking Valkem-OD 500 Tablet with food.
Dizziness and sleepiness: Consider taking this medicine at night if it makes you feel dizzy or sleepy during the day.
How Valkem Od 500 Tablet 10 Works?
Valkem-OD 500 Tablet contains Divalproex (500 mg) as its active ingredient. Here's how it works:
Increases GABA Levels: Divalproex increases the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter, a substance that helps nerve cells in the brain communicate with each other. By increasing GABA, Divalproex helps calm nerve activity.
Stabilises Electrical Activity: The increased GABA levels help stabilise electrical activity in the brain. This helps reduce the occurrence of seizures and manic episodes, thereby managing conditions like epilepsy and bipolar disorder.
Modulates Neurotransmitters: Divalproex also helps in the prevention of migraines by modulating, or adjusting, the neurotransmitters involved in pain signalling within the brain. This helps reduce the frequency and intensity of migraine headaches.
Safety Measures & Warnings
Pregnancy
Valkem-OD 500 Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Breastfeeding
Caution is advised while taking Valkem-OD 500 Tablet if you are breastfeeding. It's important to consult your doctor to understand the potential risks and benefits.
Alcohol
While taking Valkem-OD 500 Tablet, it's recommended to limit your alcohol intake. Excessive alcohol consumption could amplify the medicine's side effects and reduce its effectiveness.
Liver
Caution is advised while taking Valkem-OD 500 Tablet if you have liver health issues. This medicine may affect liver function, so it's essential to discuss your liver health with your doctor before starting this medication.
Kidney
If you have a history of kidney problems, caution is advised before using Valkem-OD 500 Tablet. It's a good idea to consult your doctor before starting this medication.
Using Machines & Driving
Valkem-OD 500 Tablet may cause dizziness or drowsiness, which could affect your ability to drive or operate machinery. Be cautious until you know how this medication affects you.
Allergy
Valkem-OD 500 Tablet should not be used if you're allergic to divalproex sodium or any of the ingredients in the tablet. If you've had allergic reactions to similar medicines in the past, discuss this with your doctor.
Children
Valkem-OD 500 Tablet is not typically recommended for children under 18 years of age. Always consult your doctor before giving this medicine to a child.
Older Patients
Older patients should take Valkem-OD 500 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised, particularly if patients are above 70 years of age. Your doctor will guide you based on your health status.
Interactions of Valkem Od 500 Tablet 10
Drug-Drug Interactions
Valkem-OD 500 Tablet interacts with the following medicines:
Anticoagulants: Blood-thinning medications like warfarin may interact with Valkem-OD 500 Tablet, possibly enhancing their blood-thinning effect.
Antidepressants: SSRIs and MAOIs, such as fluoxetine and phenelzine, may have altered effects when taken with this medicine.
Antipsychotics: Medications like quetiapine and olanzapine may interact with Valkem-OD 500 Tablet, potentially leading to an increase in side effects.
Benzodiazepines: Medicines such as diazepam and lorazepam may have enhanced sedative effects when taken with this medicine.
Carbapenem antibiotics: Medications like meropenem may reduce the effectiveness of Valkem-OD 500 Tablet.
Drug-Food Interactions
The consumption of certain foods can influence the action of Valkem-OD 500 Tablet:
Grapefruit Juice: Taking grapefruit juice while taking this medication could cause an increase in its levels in your body.
Drug-Disease Interactions
Valkem-OD 500 Tablet interacts with the following diseases:
Liver disease: If you have liver disease, using this medication could further affect your liver function.
Dosage of Valkem Od 500 Tablet 10
Daily Dose
Your doctor will prescribe the daily dose of Valkem-OD 500 Tablet for you. This will depend on factors such as your health condition and how you respond to the medicine. Always follow your doctor's instructions and never increase the dosage without consulting them.
Over Dose
In case you accidentally take more than the prescribed dose of Valkem-OD 500 Tablet, you may experience side effects such as nausea, vomiting, and dizziness. If these symptoms persist or worsen, inform your doctor.
Missed Dose
If you forget to take your Valkem-OD 500 Tablet, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and carry on with your regular schedule. Never double your dose to make up for a missed one. Always consult your doctor before making any changes to your dosage regimen.
Storage
Store Valkem-OD 500 Tablet at room temperature, ideally below 30°C.
Avoid exposure to excessive light and moisture.
Keep this medicine in a secure location, out of reach of children and pets.
Always check the expiry date on the packaging before use.
Diet & Lifestyle
For those using Valkem-OD 500 Tablet for epilepsy, it can be beneficial to maintain a regular eating schedule. Sudden changes in meal times can sometimes trigger seizures.
If you're taking this medicine for bipolar disorder, engaging in regular physical activity like walking or yoga can help manage mood swings. Consult your doctor about the right kind of exercise for you.
Fact Box
| Available Dosage Types | Tablet Sr |
| Habit Forming | No |
| Ailment | Epilepsy, Bipolar Disorder, Migraines |
| Drug Category | Anticonvulsant, Mood-Stabiliser |
| Therapeutic Category | Neurology |
Frequently Asked Questions (FAQs)
What is Valkem-OD 500 Tablet used for?
Valkem-OD 500 Tablet is used to manage epilepsy, bipolar disorder and to prevent migraines in adults.
How does Valkem-OD 500 Tablet work?
This medicine increases levels of a calming chemical in the brain, helping to control seizures, stabilise mood, and prevent migraines.
Is it safe to consume alcohol while taking Valkem-OD 500 Tablet?
You should avoid consuming alcohol while on this medication, as it may increase the risk of side effects. Always consult your doctor for advice.
Can I take Valkem-OD 500 Tablet during pregnancy?
This medicine can cause birth defects, so pregnant women should avoid it. Women of childbearing age should use effective contraception while taking this medication.
How should I store Valkem-OD 500 Tablet?
Store this medicine at room temperature (below 30°C), protected from light and moisture, and out of reach of children and pets.
Can I crush or chew Valkem-OD 500 Tablet?
No, you should swallow the tablet whole. Crushing or chewing it can interfere with its extended-release properties.
What should I do if I forget to take a dose of Valkem-OD 500 Tablet?
Take the missed dose as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule.
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Manufacturer details
Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: June 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
FDA. (2011). Depakote (divalproex sodium) Tablets for Oral use (pp. 1–57). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018723s037lbl.pdf
HIGHLIGHTS OF PRESCRIBING INFORMATION. (2023). [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/021168s044lbl.pdf
DailyMed - DIVALPROEX SODIUM capsule, coated pellets. (n.d.). https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=71e803ef-f684-dc73-9612-9c05cb091405&version=7
Divalproex sodium | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/salts/DBSALT000185
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346
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