Tenelidib M 500 Sr Tablet 10

Helios Pharmaceuticals

Strip of 10 Units

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MRP ~~₹157.5~~

₹78.75

₹15.75/Units

50% off

*MRP inclusive of all taxes

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15 days Easy returns

Prescription required for this medicine

Store Below 30° C

Composition

Metformin (500 Mg) + Teneligliptin (20 Mg)

Tenelidib M 500 Sr Tablet 10 is used to manage Type 2 Diabetes Mellitus when diet and exercise alone are insufficient for blood sugar control. This medication combines Teneligliptin (a DPP-4 inhibitor) and Metformin 500 mg (a biguanide) in a Sustained Release (SR) formulation to improve insulin sensitivity and lower glucose production by the liver. Please consult your doctor for the correct dosage to achieve optimal glycemic control.

The dual-action formula helps stimulate insulin release, effectively preventing blood sugar spikes. Before starting this treatment, inform your healthcare provider about any pre-existing medical conditions or ongoing medications. Consistent use as prescribed is essential for effective long-term diabetes management.

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Tenelidib M 500 Sr Tablet 10 is used to manage type 2 diabetes mellitus by helping control blood sugar levels. It works by improving insulin sensitivity and lowering blood glucose, providing better glycemic control when diet and exercise alone are not sufficient.

Swallow the tablet whole with a glass of water during a meal.
Do not split, crush, or chew the tablet; it must be swallowed whole.
Never exceed the recommended dose without consulting your doctor.
It's crucial not to stop taking this medicine without speaking to your doctor first.

Tenelidib M 500 Sr Tablet 10 is taken orally.

Tenelidib M 500 Sr Tablet 10 may cause side effects such as diarrhoea, nausea, vomiting, abdominal discomfort, headache, and indigestion. If these persist, consult your doctor.

Management Of Side Effects:

Most side effects are temporary and generally harmless which resolve upon discontinuing the use of Tenelidib M 500 Sr Tablet 10. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor.

Here are a few tips for managing common side effects:

Diarrhoea: You could try taking your medication with food.
Indigestion: If you're experiencing indigestion, consider taking this medicine after meals to lessen this effect.

Tenelidib M 500 Sr Tablet 10 combines two active ingredients:

Metformin (500 mg): As a biguanide antihyperglycemic agent, metformin enhances glucose tolerance in individuals with type 2 diabetes. It accomplishes this by reducing glucose production in the liver and decreasing glucose absorption in the intestines. Additionally, it helps increase peripheral glucose uptake and utilisation, thereby improving insulin sensitivity.
Teneligliptin (20 mg): Classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, teneligliptin works by slowing down the inactivation of incretin hormones. This process increases their concentrations in the bloodstream, leading to reduced fasting and postprandial glucose levels in a glucose-dependent manner among patients with type 2 diabetes.

Pregnancy

If you're pregnant, it's best to be cautious when taking Tenelidib M 500 Sr Tablet 10. Discuss this with your doctor before starting this medication.

Breastfeeding

Metformin is known to be excreted into human milk, while the effects of Teneligliptin on breastfed infants are unknown. If you're breastfeeding, consult your doctor before using this medicine.

Alcohol

Combining alcohol with this medicine could increase the risk of lactic acidosis, a serious medical condition. It's advised that you limit your alcohol intake while on this medication.

Liver

If you have liver issues, use Tenelidib M 500 Sr Tablet 10 with caution. This medicine may affect liver function. Before starting, discuss your liver health with your doctor.

Kidney

This medicine is not used in patients with severe renal impairment. If you have kidney problems, it's important to consult your doctor before taking this medicine.

Use In Driving And Operating Machinery

No specific precautions are necessary when driving or using machines while taking Tenelidib M 500 Sr Tablet 10.

Allergy

If you know you're allergic to metformin, teneligliptin or any of the other ingredients in this medicine, avoid using Tenelidib M 500 Sr Tablet 10.

Children

The safety and effectiveness of Tenelidib M 500 Sr Tablet 10 for children have not been established. Always consult your doctor before giving this medicine to individuals under 18 years of age.

Older Patients

Older patients should take Tenelidib M 500 Sr Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Tenelidib M 500 Sr Tablet 10 may interact with the following medicines:

CYP3A4 or P-gp inhibitors like ketoconazole or atazanavir may interact with Tenelidib M 500 Sr Tablet 10, potentially increasing the plasma concentrations of teneligliptin.
Anticoagulants such as phenprocoumon or acenocoumarol may have reduced effects when taken with Tenelidib M 500 Sr Tablet 10 due to metformin's influence.
Thyroid hormone supplements: Levothyroxine's effectiveness can be decreased by the presence of this medicine.
ACE Inhibitors like enalapril or lisinopril, when used with Tenelidib M 500 Sr Tablet 10, can increase the hypoglycemic effect.

Drug-Food Interactions

None

Drug-Disease Interactions

Tenelidib M 500 Sr Tablet 10 can interact with the following diseases:

Renal Disease: Severe renal impairment can result in adverse reactions when this medicine is used.
Hepatic Impairment: This medicine should be used with caution in patients with liver disease.
Metabolic Acidosis: Patients diagnosed with metabolic acidosis, including diabetic ketoacidosis, should avoid using this medicine.

Daily Dose

It's crucial that you take your daily dose of Tenelidib M 500 Sr Tablet 10 as prescribed by your doctor. Dosage may vary depending on individual factors such as your health condition and how you respond to the medicine. Always stick to the dosage recommended by your doctor, and never alter it without seeking medical advice.

Over Dose

In the case of an overdose, you might experience common side effects in a more pronounced way. However, it's always better not to panic and calmly inform your doctor about the situation. Remember, following the prescribed dosage helps prevent such situations.

Missed Dose

If you've missed a dose of Tenelidib M 500 Sr Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't adjust your dosage or frequency without consulting your doctor.

Store Tenelidib M 500 Sr Tablet 10 in a dry place below 30°C.
Shield it from light to maintain its effectiveness.
Keep this medicine unreachable for children, ensuring their safety.
Always check the expiration date before using the tablet.

Incorporate a balanced diet rich in fibre and low in simple sugars to help manage your blood sugar levels.
Regular physical activity like walking or yoga can also support glucose control, but always consult your doctor before starting any new exercise regimen.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus
Drug Category	Biguanide Antihyperglycemic, DPP-4 Inhibitor
Therapeutic Category	Antidiabetic

What is Tenelidib M 500 Sr Tablet 10 used for?

This medicine is used to manage type 2 diabetes in adults when single therapy with either metformin or teneligliptin doesn't effectively control blood sugar.

How does Tenelidib M 500 Sr Tablet 10 work?

Metformin in this tablet reduces glucose production in the liver, enhances glucose uptake and use, while teneligliptin increases insulin release and reduces glucagon secretion.

Can I take Tenelidib M 500 Sr Tablet 10 during pregnancy?

It's best to consult your doctor. There aren't sufficient studies about its use during pregnancy, so it should be used only if clearly needed.

Is Tenelidib M 500 Sr Tablet 10 safe for nursing mothers?

Metformin is known to pass into human milk, but the effect on a breastfed infant is unknown. Therefore, consult with your doctor before using this medicine on such occasions.

Can children take Tenelidib M 500 Sr Tablet 10?

The safety and effectiveness of this medicine haven't been established for paediatric use. It's meant for adults and should be given to children only if prescribed by a doctor.

What happens if I overdose on Tenelidib M 500 Sr Tablet 10?

Overdose can lead to serious conditions like lactic acidosis. Immediate medical attention is required in case of an overdose.

What should I do if I have severe joint pain after taking this medicine?

Severe and disabling joint pain can occur with DPP-4 inhibitors like teneligliptin. If you experience severe joint pain, consult your doctor.

Last Updated On 27 Mar. 2026 | 10:01AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 4 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

659/1, Gulbai Tekra, 2nd Lane Panchwati, Ahmedabad, Gujarat 380006

Country of origin: INDIA

Expiry on or after: August 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Medlineplus. (n.d.). Metformin. Retrieved from https://medlineplus.gov/druginfo/meds/a696005.html
National Center for Biotechnology Information. (2013). Efficacy and safety of teneligliptin, a novel dipeptidyl peptidase-4 inhibitor, in Korean patients with type 2 diabetes mellitus: a 24-week multicentre, randomized, double-blind, placebo-controlled phase III trial. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3650886/
U.S. Food and Drug Administration. (2006). FDA Approved Drug Products: Metformin Hydrochloride. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
PubChem. (n.d.-aj). Metformin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/metformin
PubChem. (n.d.-az). Teneligliptin. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Teneligliptin
Teneligliptin: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11950

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.

CIN: U62099MH2019PTC320566

Telephone:09240250346

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Email: grievance-officer@truemeds.in

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