Sitakraft M 500 Tablet 15 is a combination medicine used to help control blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise alone are not sufficient. Lowering blood sugar helps reduce the long-term risk of serious complications such as kidney damage, nerve problems, blindness, and heart disease.
It contains sitagliptin, a DPP-4 inhibitor that helps the body release more insulin after meals, and metformin, a biguanide that improves insulin sensitivity and reduces glucose production by the liver. Take it with food as prescribed to reduce stomach upset. Continue taking it regularly even if you feel well, and do not stop taking it without consulting your doctor.
A balanced diet with controlled carbohydrate intake and regular physical activity are essential parts of managing diabetes. Keeping a healthy weight and routinely monitoring blood sugar levels support better glucose control alongside this medication.
Before starting this medicine, inform your doctor if you have any kidney or liver problems, pancreas issues, or a history of severe allergic reactions. It is not recommended during pregnancy or breastfeeding. Contact your doctor immediately if you experience persistent nausea, severe stomach pain, or fast breathing.
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FLAT 27% off on first order
Sitakraft M 500 Tablet 15
Mankind Prime Labs Private Limited
Strip of 15 Units
MRP ₹223.77
₹111.89
₹7.46/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Sitakraft M 500 Tablet 15
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Uses of Sitakraft M 500 Tablet 15
Sitakraft M 500 Tablet 15 is used in the long-term management of type 2 diabetes mellitus to help maintain steady blood sugar control and prevent complications.
Uses of Sitakraft M 500 Tablet 15 are:
- Type 2 Diabetes Mellitus: Helps control high blood sugar levels in adults when single-drug therapy, diet, and exercise are insufficient.
- Complication Prevention: Lowers the risk of long-term diabetes-related complications such as kidney damage, nerve pain, and vision loss.
Directions for Use of Sitakraft M 500 Tablet 15
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
If you miss a dose, take it as soon as you remember unless it's nearly time for your next dose.
Never take more than your recommended dose without consulting your doctor.
Route of Administration
Sitakraft M 500 Tablet 15 is taken orally.
Side Effects of Sitakraft M 500 Tablet 15
Sitakraft M 500 Tablet 15 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Sitakraft M 500 Tablet 15:
- Respiratory: Upper respiratory tract infections such as a cold or sore throat.
- Neurological: Headache in some cases. Staying well hydrated and taking adequate rest can help ease headaches.
- Digestive: Feeling sick (nausea), vomiting, and loose motions (diarrhoea). Taking the tablet with food helps reduce stomach upset.
- Musculoskeletal: Joint pain and general muscle weakness.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sitakraft M 500 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some ways to manage common side effects:
Diarrhoea Try taking Sitakraft M 500 Tablet 15 with meals and take plenty of fluids to avoid dehydration.
Weakness: Consider taking this medicine at night if it causes weakness during the day.
How Sitakraft M 500 Tablet 15 Works?
Sitakraft M 500 Tablet 15 consists of two active ingredients:
Sitagliptin (50 mg): This ingredient is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It regulates blood sugar by increasing insulin release from your pancreas and reducing glucagon secretion.
Metformin (500 mg): As a member of the biguanide class of medicines, metformin aids in reducing blood sugar levels through various actions. It decreases glucose production in your liver, reduces glucose absorption in your intestines, and enhances insulin sensitivity in your body.
The combined action of metformin and sitagliptin offers better control over blood sugar levels than either component alone.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Sitakraft M 500 Tablet 15 if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
It is recommended to discuss with your doctor if you are lactating before starting this medication.
Alcohol
Drinking alcohol while on Sitakraft M 500 Tablet 15 may increase the risk of lactic acidosis. It's advisable to limit or avoid alcohol consumption when using this medication.
Liver
Patients with existing liver diseases should exercise caution while taking Sitakraft M 500 Tablet 15. If you have liver problems, discuss them with your doctor before starting the medicine.
Kidney
Caution is advised before using Sitakraft M 500 Tablet 15 if you have a history of kidney problems. Consult your doctor for guidance based on your health status.
Use In Driving And Operating Machinery
There is no known impairment of the ability to drive or operate machinery while taking Sitakraft M 500 Tablet 15. However, if you experience side effects like dizziness, it's safer to avoid such activities.
Allergy
Do not take Sitakraft M 500 Tablet 15 if you are allergic to metformin, sitagliptin, or any other ingredients in the medicine. Notify your doctor about any past allergic reactions.
Children
Sitakraft M 500 Tablet 15 is not indicated for use in children below 18 years of age. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Sitakraft M 500 Tablet 15 under medical supervision as they may be more susceptible to its side effects. Caution is advised especially for patients above 80 years of age due to potential kidney health issues. Your doctor will guide you based on your health status.
Interactions of Sitakraft M 500 Tablet 15
Drug-Drug Interactions
Sitakraft M 500 Tablet 15 interacts with the following medicines:
Insulin or insulin secretagogues: Medicines like glimepiride or glibenclamide, when taken with Sitakraft M 500 Tablet 15, can increase the risk of low blood sugar or hypoglycaemia.
Diuretics: Taking diuretics such as furosemide or hydrochlorothiazide with this medicine may increase the risk of lactic acidosis.
Corticosteroids: Medicines like prednisone may reduce the blood sugar lowering effect of Sitakraft M 500 Tablet 15.
Drug-Food Interactions
Certain foods can interact with Sitakraft M 500 Tablet 15. Known interactions include:
High-fat meals: These may decrease the absorption of sitagliptin.
Drug-Disease Interactions
Sitakraft M 500 Tablet 15 interacts with the following diseases:
Heart disease: If you have heart conditions like congestive heart failure, caution is advised as this medicine could exacerbate your condition.
Liver disease: Liver problems might affect how Sitakraft M 500 Tablet 15 is broken down and removed from your body.
Dosage of Sitakraft M 500 Tablet 15
Daily Dose
Your doctor will decide the daily dose of Sitakraft M 500 Tablet 15 based on factors like your condition's severity and how you respond to the medicine. Always stick to the prescribed dosage, and don't change it without consulting your doctor.
Over Dose
If you accidentally take more Sitakraft M 500 Tablet 15 than prescribed, you might experience symptoms similar to its side effects, such as nausea or weakness. Inform your doctor if this happens.
Missed Dose
If you forget to take a dose of Sitakraft M 500 Tablet 15, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Never change your dosage without talking to your doctor.
Storage
Store your Sitakraft M 500 Tablet 15 at room temperature, not exceeding 30°C.
Protect the medicine from light and moisture; avoid storing it in the bathroom.
Always keep the tablet out of reach of children.
Special Dietary And Lifestyle Recommendation
Adopt a balanced diet rich in fibre and low in sugars. This can help manage your blood sugar levels effectively while using Sitakraft M 500 Tablet 15.
Regular physical exercise, such as walking or cycling, can also aid in managing type 2 diabetes by improving your body's insulin sensitivity.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes |
| Drug Category | Biguanide, DPP-4 Inhibitor |
| Therapeutic Category | Antidiabetic |
Frequently Asked Questions (FAQs)
What is Sitakraft M 500 Tablet 15 used for?
Sitakraft M 500 Tablet 15 is used to manage high blood sugar levels in adults with type 2 diabetes mellitus, alongside a proper diet and exercise.
How does Sitakraft M 500 Tablet 15 work?
The medicine has two active ingredients: metformin reduces liver glucose production, and sitagliptin increases insulin release, both helping to regulate blood glucose levels.
Can I miss a dose of Sitakraft M 500 Tablet 15?
If you forget to take your tablet, consume it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one.
Are there any side effects of Sitakraft M 500 Tablet 15?
Common side effects can include cold symptoms, headache, nausea, or indigestion. Serious but rare side effects require immediate medical attention. Please consult the doctor if they persist.
Who should not take Sitakraft M 500 Tablet 15?
Patients with type 1 diabetes, severe kidney impairment or known hypersensitivity to either metformin or sitagliptin should avoid this medicine.
Can I drink alcohol while taking Sitakraft M 500 Tablet 15?
Excessive intake of alcohol while on this medication should be avoided as it increases the risk of a condition called lactic acidosis.
Can Sitakraft M 500 Tablet 15 interact with other medications?
Yes, Sitakraft M 500 Tablet 15 can interact with several medications, such as insulin, diuretics, or corticosteroids. Always inform your doctor about any other medicines you are taking.
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Manufacturer details
Country of origin: INDIA
References
Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 4369359, Sitagliptin. Retrieved June 21, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Sitagliptin
Sitagliptin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01261
DailyMed - SITAGLIPTIN AND METFORMIN HYDROCHLORIDE tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e07abcb1-1f0c-4cad-8405-8eedba4b8ff8
Metformin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a696005.html
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