Siropan Tablet 10

Siropan Tablet 10 is used for the following:

• Prevention of kidney transplant rejection

• Management of immunosuppression after transplantation

• Treatment of sporadic lymphangioleiomyomatosis in women

• Supporting organ transplant maintenance therapy

• Reducing the risk of transplanted kidney failure

• Management of certain cancers under medical supervision

• Controlling excessive immune responses in transplant patients

• Preventing antibody formation against transplanted kidneys

Follow these instructions while taking the Siropan Tablet 10:

• Swallow the tablet whole with a glass of water.

• Take it consistently, either with food or without food, each time.

• Avoid consuming grapefruit or grapefruit juice during treatment.

• Do not crush, chew, or break the tablet.

• Continue taking this medicine regularly as advised by your doctor.

• If you miss a dose, take it as soon as you remember, unless it's nearly time for your next dose.

Siropan Tablet 10 is taken orally.

Siropan Tablet 10 contains Sirolimus (1 mg), which works on the body as follows:

• T-lymphocyte inhibition: Sirolimus blocks specific cell-signalling proteins that normally boost immune responses. This dampens your body's ability to mount a strong immune reaction against the transplanted organ.

• B-lymphocyte suppression: The medicine reduces the production of antibodies by B-lymphocytes. Antibodies are proteins that your immune system normally produces to fight foreign substances, but in transplant patients, they can attack the new organ.

• Immune response modulation: By affecting both T and B cells, sirolimus helps prevent your immune system from recognising and attacking the transplanted kidney as foreign tissue.

• Store Siropan Tablet 10 at room temperature below 25°C.

• Keep the tablets in their original container, away from excessive heat, humidity, and direct sunlight.

• Do not store in bathrooms where humidity levels fluctuate.

• Keep all medicines securely out of reach of children.

• Check the expiry date before use and discard any unused medicine after this date.

• Use adequate sun protection and limit sun exposure, as sirolimus increases your risk of skin cancer while managing transplant rejection.

• Because sirolimus suppresses the immune system, you’re more prone to infections. Wash your hands frequently and avoid close contact with sick individuals.