Zydus Lifesciences Limited
Strip of 6 Units
Old MRP ₹1061
MRP ₹994.69
₹795.75
₹165.78/Units
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CompositionSiromus Tablet is used to prevent the body from rejecting a transplanted kidney. It is an immunosuppressant belonging to the mTOR inhibitors class of medicines.
This medicine is also prescribed for the treatment of lymphangioleiomyomatosis (LAM), a rare progressive lung disease. Before starting this medication, consult your doctor for proper dosage and frequency.
Siromus Tablet is used for:
Here is how you should take Siromus Tablet:
Siromus Tablet is taken orally.
Siromus Tablet may have the following common side effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Siromus Tablet. However, if you experience any serious side effects or worsening of symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Siromus Tablet contains sirolimus (1 mg), which acts on the body in the following ways:
Siromus Tablet is not recommended during pregnancy unless absolutely necessary. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
Siromus Tablet is not recommended for breastfeeding women unless absolutely necessary. Consult your doctor to understand the potential risks and benefits.
It is always a good idea to avoid or limit alcohol consumption while taking this medicine. Consult your doctor regarding any concerns.
Caution is advised while taking Siromus Tablet if you have liver problems. This medicine may affect liver function, so it's important to discuss this with your doctor before starting the medication.
If you have a history of kidney issues, it's wise to consult your doctor before taking Siromus Tablet. This medicine could potentially impact kidney function.
There is no specific data suggesting that Siromus Tablet affects your ability to drive or operate machinery. However, as it can cause side effects like dizziness, caution is advised before doing activities that require alertness.
If you have ever had an allergic reaction to sirolimus or any other ingredients in Siromus Tablet, please inform your doctor.
Siromus Tablet should not be given to children under 18 years of age without consulting a doctor first.
Older patients should take Siromus Tablet under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Siromus Tablet can interact with the following medicines:
Strong CYP3A4 inhibitors: Medicines like ketoconazole, itraconazole, and clarithromycin can increase the levels of sirolimus in your blood.
Strong CYP3A4 inducers: Medicines such as rifampin and St. John's wort can decrease sirolimus concentrations in your body.
Immunosuppressants: Other immunosuppressant medicines like cyclosporine when used together, Siromus Tablet may increase the harmful effects of cyclosporine on your kidneys.
Live vaccines: If you're taking Siromus Tablet, avoid live vaccines due to the risk of vaccine-associated infection.
Certain food items can interact with Siromus Tablet:
Grapefruit and grapefruit juice: These can increase sirolimus levels in your blood.
Siromus Tablet may interact with the following diseases:
Liver disease: If you have liver issues, Siromus Tablet should be used with care, as it may worsen your condition.
Hyperlipidaemia: Patients with this condition should be cautious when taking Siromus Tablet, as it may increase cholesterol and triglyceride levels in the blood.
Skin cancer: You are at a higher risk of developing skin cancer if you're taking Siromus Tablet, so ensure to protect yourself from sun exposure.
Your daily dose of Siromus Tablet should be as prescribed by your doctor. It's crucial to adhere to this dosage, as it may vary based on your specific condition and how your body responds to the medication. For more details regarding the dosage, please refer to the package insert.
In case you accidentally take more than the recommended amount of Siromus Tablet, you could experience symptoms such as diarrhoea, abdominal pain, and headaches. If these symptoms persist, do inform your doctor.
If you forget to take your Siromus Tablet at the usual time, simply take it as soon as you remember. But if it's nearly time for your next dose, just skip the missed one and continue with your regular schedule. Never change your dosage without consulting your doctor.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Organ rejection prevention, Lymphangioleiomyomatosis (LAM) |
| Drug Category | mTOR Inhibitor |
| Therapeutic Category | Immunosuppressant |
Siromus Tablet is primarily used to prevent organ rejection in kidney transplant patients when combined with other medicines.
Siromus Tablet works by suppressing the body's immune response, preventing it from rejecting a transplanted kidney as a foreign object.
Always consult your doctor for specific guidance on the use of this medicine, who will advise whether you can take this medication with or without food.
Yes, grapefruit and grapefruit juice should be avoided, as they can increase sirolimus levels in your blood.
Yes, side effects may include peripheral oedema (swelling of the extremities due to fluid accumulation), hypertension (increased blood pressure), abdominal pain, diarrhoea, headache, and fever, among others. Consult your doctor if these persist.
Avoid exposure to sunlight and UV light. Maintain good oral hygiene and consult your doctor regularly to monitor your health.
Yes, it can interact with certain medications like cyclosporine and some antifungal medicines like ketoconazole or itraconazole. Always inform your doctor about all medicines you are currently taking.
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