Silosine 4 Tablet 10 is a commonly prescribed treatment for managing the symptoms of benign prostatic hyperplasia (BPH) in adult men, a condition characterised by the non-cancerous enlargement of the prostate gland. It falls under a class of medications known as alpha-1 blockers.
This tablet is also beneficial for alleviating common urinary issues associated with BPH, including difficulty in starting urination, weak urine flow, and the bothersome feeling of incomplete bladder emptying. Additionally, this tablet helps reduce the need for frequent urination, especially at night, and addresses the sudden, urgent need to urinate, improving overall quality of life.
Before commencing this medication, consulting with your doctor is essential to determine the appropriate dosage and frequency, ensuring that it suits your specific health requirements. If you have existing health conditions or are taking other medications, it’s crucial to inform your doctor, as these factors may influence how safely and effectively this tablet works for you. Should any side effects occur, seek medical guidance promptly.
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Silosine 4 Tablet 10
Strip of 10 Units
Old MRP ₹159
MRP ₹149.06
₹74.53
₹14.91/Units
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Store Below 30° C
CompositionAbout Silosine 4 Tablet 10
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Uses of Silosine 4 Tablet 10
Silosine 4 Tablet 10 is used for the following:
- Reducing symptoms of non-cancerous prostate gland enlargement
- Assisting in initiating urination when it is difficult
- Improving weak urine flow
- Lowering the frequency of nighttime urination
- Reducing the sensation of incomplete bladder emptying
- Controlling sudden, urgent urges to urinate
Directions for Use of Silosine 4 Tablet 10
- Take the tablet orally with water or as prescribed by the doctor.
- Avoid chewing or crushing the tablet.
- Take it with a meal for its better absorption and to avoid stomach upset.
- Consult your doctor if you have any doubts about how to take this medicine.
Route of Administration
Silosine 4 Tablet 10 is taken orally.
Side Effects of Silosine 4 Tablet 10
Silosine 4 Tablet 10 may have the following common side effects:
- Dizziness
- Diarrhoea
- Headaches
- Nasal congestion
- Orthostatic hypotension: It means that your blood pressure might drop when you stand up from sitting or lying down.
Management Of Side Effects:
Most side effects are temporary, generally harmless, and resolve upon discontinuing the use of Silosine 4 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
- Dizziness: Avoid getting up too quickly from a sitting or lying position to help manage this effect.
- Diarrhoea: Try taking Silosine 4 Tablet 10 with food to lessen this effect.
How Silosine 4 Tablet 10 Works?
Silosine 4 Tablet 10 contains silodosin (4 mg), an active compound that targets alpha-1A adrenergic receptors found in the prostate and bladder neck:
- Blocking Alpha-1A Receptors: Silodosin blocks alpha-1A adrenergic receptors, primarily found in the prostate and bladder neck.
- Relaxing Muscles: By blocking these receptors, silodosin helps relax the smooth muscles in these tissues, enhancing urine flow and easing BPH symptoms.
Safety Measures & Warnings
Alcohol
Consuming alcohol while taking Silosine 4 Tablet 10 can amplify its blood pressure-lowering effects, which may lead to an increased risk of dizziness or even fainting. Exercise caution when taking this medication, as it may heighten these side effects.
Liver
Silosine 4 Tablet 10 should be used with caution if you have mild to moderate liver impairment. If you have any liver-related health conditions, it is essential to discuss these with your doctor prior to beginning treatment with this tablet, as your doctor may need to adjust your dose or monitor you more closely.
Kidney
For patients with moderate kidney impairment, dose adjustments are usually necessary. Silosine 4 Tablet 10 is not recommended for individuals with severe kidney impairment due to the risk of adverse effects. If you have any kidney-related health issues, always consult your doctor before starting this medication to ensure it is safe for you.
Use In Driving And Operating Machinery
Silosine 4 Tablet 10 may cause dizziness, particularly with the first dose or until your body adjusts to the medication. Until you understand how this tablet affects you, it is advised to avoid driving or operating heavy machinery, as your ability to perform these tasks safely may be compromised.
Allergy
Do not take Silosine 4 Tablet 10 if you are allergic to silodosin or any components of this tablet.
Children
Silosine 4 Tablet 10 is not indicated for children under the age of 18. Always seek medical advice before giving any medication to a child to ensure their safety and suitability.
Older Patients
Older male patients, particularly those over 70 years of age, should take Silosine 4 Tablet 10 under close medical supervision, as they may be more sensitive to the medication’s side effects. Your doctor will assess your health and guide you on the appropriate usage, taking into account any potential risks associated with age.
Interactions of Silosine 4 Tablet 10
Drug-Drug Interactions
Silosine 4 Tablet 10 interacts with the following medicines:
- Strong CYP3A4 Inhibitors: Medicines like ketoconazole, itraconazole, ritonavir, or clarithromycin may increase silodosin levels in the bloodstream, elevating its effects.
- Strong P-glycoprotein inhibitors: Medicines line cyclosporine, when co-administered, may increase plasma silodosin concentration. Concomitant use is not recommended.
Drug-Food Interactions
Silosine 4 Tablet 10 is known to interact with certain types of food:
- High-fat meals: High-fat meals can increase the absorption of silodosin, possibly intensifying its effects. It is advisable to take this tablet as directed without such meals.
Drug-Disease Interactions
Silosine 4 Tablet 10 interacts with the following diseases:
- Kidney Impairment: Severe kidney impairment can lead to increased levels of silodosin. Avoid Silosine 4 Tablet 10 if you have serious kidney issues.
- Liver Impairment: Severe liver issues are also contraindications for Silosine 4 Tablet 10. Consult a doctor if you have a history of liver disease.
- Other Alpha-Blockers: Combining this tablet with other alpha-blockers, such as doxazosin or tamsulosin, could cause excessive blood pressure lowering.
Dosage of Silosine 4 Tablet 10
Daily Dose
The recommended daily dose of Silosine 4 Tablet 10 should be taken as per your doctor's advice. It varies depending on factors like the severity of your condition and how you respond to the medicine. Always adhere to the prescribed dosage and never alter it without consulting your doctor.
Over Dose
Taking too many Silosine 4 Tablet 10 may lead to an increase in side effects such as dizziness, diarrhoea, or headaches. If you think you've taken more than the prescribed dosage, inform your doctor.
Missed Dose
If you forget to take a dose of Silosine 4 Tablet 10, take it as soon as you can. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not alter your dosage without your doctor's advice.
Storage
- Store Silosine 4 Tablet 10 at room temperature, ideally below 30°C.
- Protect from light and moisture by keeping the medicine in its original package.
- Always keep this medication out of reach of children.
- Check the expiration date, and make sure to use it before that.
Special Dietary And Lifestyle Recommendation
- Limit Caffeine: High caffeine intake can irritate the bladder and prostate, potentially worsening BPH symptoms.
- Regular Exercise: Engaging in physical activities such as brisk walking for 30 minutes on most days can aid in managing BPH symptoms and support overall health.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Benign Prostatic Hyperplasia |
| Drug Category | Alpha-1 Blocker
|
| Therapeutic Category | Urological Agent
|
Frequently Asked Questions (FAQs)
What is Silosine 4 Tablet 10 used for?
How does Silosine 4 Tablet 10 work?
Can I take Silosine 4 Tablet 10 to manage high blood pressure?
Is Silosine 4 Tablet 10 safe for everyone?
What are the common side effects of Silosine 4 Tablet 10?
Can I take other alpha-blockers while on Silosine 4 Tablet 10?
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Manufacturer details
Country of origin: INDIA
References
- RAPAFLO® (silodosin) Capsule for oral use(N.d.). Fda.Gov. Retrieved November 2, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022206s012lbl.pdf
- Silodosin. (n.d.). Medlineplus.Gov. Retrieved November 2, 2024, from https://medlineplus.gov/druginfo/meds/a609002.html
- National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 5312125, Silodosin. https://pubchem.ncbi.nlm.nih.gov/compound/Silodosin
- DrugBank Online. (2024, Apr 3). Silodosin. https://go.drugbank.com/drugs/DB06207
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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