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CompositionSedogest Sr 450 Tablet 10 is used to treat cholesterol-based gallstones and manage a chronic liver disease called Primary Biliary Cirrhosis (PBC). It contains Ursodeoxycholic Acid (UDCA) 450 mg (Sustained Release), which belongs to the class of cholagogues. UDCA decreases the production of cholesterol in the liver, helping to gradually dissolve cholesterol gallstones. In PBC, it improves bile flow and liver function by replacing toxic bile acids with less harmful ones.
Sedogest Sr 450 Tablet 10 is used for dissolving cholesterol-rich gallstones in the gallbladder. It prevents the formation of gallstones in obese patients undergoing rapid weight loss. It also helps manage primary biliary cirrhosis, a chronic condition that damages bile ducts in the liver.
Swallow the tablet whole with a glass of water. Do not crush, chew or break it.
Ideally, take the tablet with food to minimise any potential digestive discomfort.
Maintain regularity by taking this medicine at approximately the same times each day.
If your doctor has advised you to adjust your dose, you can split the scored tablet in half. Always consult your doctor before making any changes to your medication regimen.
Sedogest Sr 450 Tablet 10 is taken orally.
Sedogest Sr 450 Tablet 10 may cause abdominal pain or discomfort, diarrhea, nausea, headache, dizziness, and hair loss.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sedogest Sr 450 Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some tips for managing common side effects:
Abdominal pain or discomfort: Taking Sedogest Sr 450 Tablet 10 with food can help reduce this effect.
Diarrhoea: Ensure you consume plenty of fluids throughout the day.
Sedogest Sr 450 Tablet 10 contains Ursodeoxycholic Acid (450 mg). Its activity in the body includes:
Cholesterol Reduction: Ursodeoxycholic acid decreases cholesterol secretion into bile by inhibiting its absorption in your gut and suppressing its synthesis in your liver. This reduces the saturation of bile with cholesterol.
Gallstone Management: It increases the solubility of cholesterol in bile, dissolving stones and preventing new stone formation.
Bile Flow Improvement: It has immunomodulating and anti-inflammatory properties that improve bile flow in PBC and protect liver cells.
The sustained-release nature of Sedogest Sr 450 Tablet 10 ensures these effects are maintained over a 24-hour period.
Caution is advised while taking Sedogest Sr 450 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.
If you are breastfeeding, make sure to discuss this with your doctor before starting Sedogest Sr 450 Tablet 10.
There's no known interaction of Sedogest Sr 450 Tablet 10 with alcohol. However, it's always wise to consult your doctor for clarity.
Sedogest Sr 450 Tablet 10 is used to treat certain liver conditions like PBC. However, it should not be used in advanced liver failure or decompensated cirrhosis unless your doctor advises otherwise.
While there’s limited data in severe kidney disease, Sedogest Sr 450 Tablet 10 is generally considered safe. Consult your doctor if you have kidney issues.Caution is advised before using Sedogest Sr 450 Tablet 10 if you have a history of any kidney problems. It's a good idea to consult your doctor before taking this medicine.
Sedogest Sr 450 Tablet 10 may cause dizziness in some cases. If you experience this, avoid driving or operating heavy machinery until you feel comfortable.
If you're allergic to bile acids or any components of Sedogest Sr 450 Tablet 10, avoid using the medicine. Discuss your allergies with your doctor for safer alternatives.
"Sedogest Sr 450 Tablet 10 may be prescribed in children under specialist supervision, particularly for pediatric liver disorders. Always follow your doctor's guidance."
Older patients should take Sedogest Sr 450 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age due to potential liver and kidney issues. Your doctor will guide you based on your health status.
Sedogest Sr 450 Tablet 10 interacts with the following medicines:
Antacids and bile acid sequestrants: Medicines like aluminium hydroxide and cholestyramine may decrease the absorption of Sedogest Sr 450 Tablet 10, making it less effective.
Clofibrate and oestrogens: These medications, such as ethinyl estradiol and clofibrate, can increase the risk of gallstones when taken along with Sedogest Sr 450 Tablet 10.
Antibiotcs: Sedogest Sr 450 Tablet 10 may increase the absorption of ciprofloxacin and nitrendipine, potentially enhancing their effects.
No specific food interactions have been reported with Sedogest Sr 450 Tablet 10.
Sedogest Sr 450 Tablet 10 interacts with the following diseases:
Liver disease: People with liver disease should use Sedogest Sr 450 Tablet 10 cautiously as it could exacerbate their condition.
Kidney disease: Caution is advised for individuals with kidney problems as this medication could potentially worsen their condition.
Take your daily dose of Sedogest Sr 450 Tablet 10 as directed by your doctor. The dosage depends on individual factors like the severity of the condition and your response to the medicine. Always follow the prescribed dosage and never exceed it without consulting your doctor.
If you accidentally take more than the recommended dose of Sedogest Sr 450 Tablet 10, you may experience common side effects like abdominal discomfort and diarrhoea. If these symptoms persist or worsen, inform your doctor.
Should you forget to take your regular dose of Sedogest Sr 450 Tablet 10, take it as soon as you remember. If it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Store Sedogest Sr 450 Tablet 10 in a cool, dry place below 30°C.
Keep it away from direct sources of heat, light and moisture.
Always ensure the medicine is kept safely out of reach of children.
Do remember to check the expiry date and avoid using the medicine post this date.
If you're taking Sedogest Sr 450 Tablet 10 for gallstones, try adopting a diet low in fats and cholesterol. This can help reduce cholesterol build-up in the gallbladder.
For those managing primary biliary cirrhosis (PBC), consider reducing your intake of salt and increasing fluids. This can help manage swelling associated with PBC.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Gallstones, Primary Biliary Cirrhosis |
| Drug Category | Bile Acid |
| Therapeutic Category | Hepatoprotective |
Sedogest Sr 450 Tablet 10 is primarily used to dissolve gallstones, prevent gallstone formation during rapid weight loss, and manage primary biliary cirrhosis.
It works by reducing cholesterol in bile and increasing its solubility. This helps dissolve gallstones and prevents new ones from forming. It also improves bile flow.
If you're pregnant or planning to conceive, consult your doctor before taking this medicine.
Swallow the tablet whole with water. Take it with food to minimise digestive side effects. Remember to take it regularly at the same time each day.
Common side effects include abdominal pain, diarrhoea, nausea, headache, dizziness, and hair loss. Usually, these do not require medical attention.
Yes, use it with caution if you have liver or kidney disease. Also, stop use and inform your doctor if you develop signs of liver trouble.
Yes, medicines like antacids, bile acid sequestrants, clofibrate and estrogen can interact with Sedogest Sr 450 Tablet 10. Always tell your doctor about all the medicines you take.
Check out Editorial Policy
Axcan Pharma US, Inc. (2009). HIGHLIGHTS OF PRESCRIBING INFORMATION: URSO 250 / URSO Forte (ursodiol) TABLETS [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020675s017lbl.pdf
Aptalis Pharma Canada ULC. (2023). Urso / Urso DS (ursodiol). https://pdf.hres.ca/dpd_pm/00069724.PDF
DailyMed - URUSA- ursodeoxycholic acid capsule. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7aa650ea-167b-cdd8-e053-2991aa0a7896
Ursodeoxycholic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01586
Achufusi, T. G. O., Safadi, A. O., & Mahabadi, N. (2023, February 12). Ursodeoxycholic acid. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK545303/
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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