Polmakem Capsule: Uses, Side Effects, Price & Substitutes

About Polmakem Capsule 10

POLMAKEM CAPSULE 10 is a medicine used to manage joint pain and inflammation in adults with osteoarthritis of the hip and knee. It helps improve joint mobility and ease daily physical activities, with therapeutic benefits building gradually over several weeks.

It contains polmacoxib, a COX-2 selective nonsteroidal anti-inflammatory drug (NSAID). Take it with food as prescribed to help reduce stomach irritation. It is important to continue taking it regularly as directed by your doctor to achieve consistent pain relief.

Combining treatment with gentle, low-impact physical exercise (such as swimming or walking), maintaining a healthy body weight, and attending joint care appointments supports long-term joint health alongside this medicine.

Before taking this medicine, tell your doctor if you have kidney, liver, or heart problems, high blood pressure, or a history of stomach ulcers. Stop taking the medicine and seek urgent medical advice if you notice dark tarry stools, severe stomach pain, or yellowing of the skin or eyes.

How does Polmakem Capsule 10 work?

Polmakem Capsule 10 works by blocking an enzyme called cyclooxygenase-2 (COX-2). This reduces inflammation and pain in your joints by decreasing the production of substances that cause swelling.

What is Polmakem Capsule 10 used for?

This medicine is primarily used to manage symptoms of osteoarthritis, particularly in the knee and hip joints. It helps reduce pain and inflammation in these areas.

Can I take Polmakem Capsule 10 with food?

Yes, you should take this medicine with food. This helps reduce the chance of stomach upset or discomfort that sometimes occurs with this type of medicine.

What are the common side effects of Polmakem Capsule 10?

Common side effects may include headache, nausea, dizziness, stomach pain, heartburn, constipation, or diarrhoea. These usually improve as your body adjusts to the medicine.

Can I drive after taking Polmakem Capsule 10?

Some people may experience dizziness after taking this medicine. If you feel dizzy, avoid driving or operating machinery until you know how it affects you.

Can I take other medicines with Polmakem Capsule 10?

Always inform your doctor about all medicines you are taking. Polmakem Capsule 10 may interact with blood thinners, diuretics (water tablets), and certain other medicines.

What should I do if I experience chest pain while taking Polmakem Capsule 10?

Seek immediate medical attention if you experience chest pain, shortness of breath, or weakness. These could be signs of serious cardiovascular effects requiring urgent care.

References

Sinha, S. D., Prasad, T. B., Konatham, B., Sriramadasu, S. C., Karmakar, A., Sharma, A. K., Verma, R., Devireddy, S. R., Bandi, M. R., & Panapakam, M. (2024). Polmacoxib 2mg in patients with mild to moderate idiopathic osteoarthritis of hip/knee. A randomized, double-anonymous study. Pain Management, 14(9), 497–506. https://doi.org/10.1080/17581869.2024.2427944
DrugBank. (n.d.). Polmacoxib. Retrieved 1 April 2025, from https://go.drugbank.com/drugs/DB12399
Easwaran, R., Mistry, U. K., Bhole, M., & Peethambaran, K. (2024). Polmacoxib: A Review of the Newer Non-steroidal Anti-inflammatory Drug in Osteoarthritis. Cureus, 16(4), e58446. https://doi.org/10.7759/cureus.58446
Lee, M., Yoo, J., Kim, J. G., Kyung, H. S., Bin, S. I., Kang, S. B., Choi, C. H., Moon, Y. W., Kim, Y. M., Han, S. B., In, Y., Choi, C. H., Kim, J., Lee, B. K., & Cho, S. (2017). A Randomized, Multicenter, Phase III Trial to Evaluate the Efficacy and Safety of Polmacoxib Compared with Celecoxib and Placebo for Patients with Osteoarthritis. Clinics in Orthopedic Surgery, 9(4), 439–457. https://doi.org/10.4055/cios.2017.9.4.439
Manjula, S., & Krishna Kumar, M. (2024). Expert perspectives on polmacoxib monotherapy in the management of osteoarthritis in Indian settings. International Journal of Research in Orthopaedics, 11(1), 118–123. https://doi.org/10.18203/issn.2455-4510.intjresorthop20243896

Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.