Pentate D Tablet 10

Morepen Laboratories Limited

Strip of 10 Units

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MRP ~~₹117~~

₹58.38

₹11.7/Units

50.1% off

*MRP inclusive of all taxes

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Prescription required for this medicine

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Composition

Domperidone (10 Mg) + Pantoprazole (20 Mg)

Pentate D Tablet 10 is used to treat acid-related stomach issues like acid reflux, heartburn, and gastroesophageal reflux disease (GERD). It contains pantoprazole (20 mg) and domperidone (10 mg). Pantoprazole reduces stomach acid production, while domperidone increases the movement of the stomach and intestines.

In addition to managing GERD, it can also be used to manage indigestion and gastritis, conditions related to digestion issues and stomach lining inflammation, respectively. It proves particularly useful when these conditions do not respond adequately to a single medication.

Before starting this medicine, always inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. Remember to continue taking the medicine for the duration your doctor prescribes for optimal results.

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Pentate D Tablet 10 is used to treat acid reflux, heartburn, and gastrointestinal disorders caused by excessive stomach acid. It combines a proton pump inhibitor and a prokinetic agent to reduce acid production and improve stomach emptying. This dual mechanism relieves symptoms like acidity, nausea, and discomfort, improving digestion and preventing acid-related damage to the esophagus and stomach lining.

Here are some general instructions you need to follow while taking Pentate D Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush, chew or break the tablet.
Continue taking this medicine regularly as prescribed by your doctor, even if your symptoms improve. Stopping it too early can cause the symptoms to return. If you are unsure, consult your doctor.

Pentate D Tablet 10 is taken orally.

While taking Pentate D Tablet 10, you might experience some side effects. These can include:

Diarrhoea
Headache
Abdominal pain
Dry mouth
Dizziness
Rash

Managing the Side Effects:

Most common side effects are temporary and generally harmless, resolved by discontinuing Pentate D Tablet 10. However, if you experience serious side effects or worsening symptoms, please consult your doctor.

Here's how you can manage some common side effects:

Diarrhoea: Try taking Pentate D Tablet 10 with food to lessen this effect.
Abdominal pain: If this medication causes stomach discomfort, consider taking it after meals.

Pentate D Tablet 10 comprises two active ingredients that work together in managing your symptoms:

Pantoprazole (20 mg): This ingredient is a proton pump inhibitor (PPI). It works by binding to and inhibiting a system in your stomach cells called the H+/K+ ATPase enzyme system or proton pump. This action reduces the production of acid in your stomach.
Domperidone (10 mg): This ingredient acts as a prokinetic agent, which helps increase the movement in your upper gastrointestinal tract, preventing stomach contents from flowing back into the food pipe. It does so by blocking certain receptors in your gut known as dopamine receptors, thereby reducing nausea and vomiting.

Pregnancy

Caution is advised while taking Pentate D Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

The safety of Pentate D Tablet 10 during breastfeeding is not established. Consult your doctor if you are breastfeeding.

Alcohol

It is advised to avoid the consumption of alcohol to avoid any adverse effects if this medication is prescribed to you.

Liver

Pentate D Tablet 10 is contraindicated in cases of moderate to severe liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before taking Pentate D Tablet 10 if you have a history of kidney problems. It's a good idea to consult your doctor first.

Using Machines & Driving

Pentate D Tablet 10 may cause drowsiness or dizziness. Be careful when driving or operating machinery until you know how this medicine affects you.

Allergy

Do not take Pentate D Tablet 10 if you are allergic to domperidone, pantoprazole, substituted benzimidazoles or any other ingredients in the formulation.

Children

Pentate D Tablet 10 should only be used by adults. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Pentate D Tablet 10 under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pentate D Tablet 10 interacts with the following medicines:

Antifungals: Medicines such as ketoconazole can increase the levels of domperidone, altering its effectiveness.
Antiarrhythmics: Medicines like amiodarone and dronedarone can potentially escalate the risk of cardiac side effects when used with this medication.
Antidepressants: Medicines like citalopram and escitalopram may interact with Pentate D Tablet 10, increasing the risk of irregular heartbeats.
Antipsychotics: Medications such as haloperidol can interact with domperidone, leading to an elevated risk of heart rhythm disorders.

Drug-Food Interactions

Pentate D Tablet 10 interacts with the following foods:

Spicy and acidic foods: Foods that are highly acidic or spicy can irritate the stomach lining and may reduce the effectiveness of Pantoprazole. It's best to avoid such foods.
Grapefruit and grapefruit juice: Grapefruit can affect the metabolism of many medications, including Domperidone, leading to increased blood levels and potential side effects. It is advisable to avoid grapefruit and grapefruit juice.

Drug-Disease Interactions

Pentate D Tablet 10 interacts with the following diseases:

Heart Disease: Patients suffering from heart conditions could face an increased risk of irregular heart rhythms when using this medication.
Gastrointestinal Conditions: Due to its prokinetic action, Pentate D Tablet 10 might worsen the condition of those with gastrointestinal bleeding, obstruction, or perforation.

Daily Dose

Adhere to the recommended dose of Pentate D Tablet 10 as directed by your doctor. Your doctor may adjust this based on factors such as your condition's severity and how you respond to the medication. Always follow this prescribed dosage and refrain from exceeding it without consulting your doctor.

Over Dose

Overdosing on Pentate D Tablet 10 may result in symptoms like confusion, drowsiness, and unusual body movements. If you suspect an overdose, contact your doctor.

Missed Dose

If you forget to take your dose of Pentate D Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Avoid increasing your dosage without consulting your doctor.

Store Pentate D Tablet 10 below 25°C in a dry and cool place.
Keep it away from direct sunlight and moisture.
Make sure to keep this medicine out of the reach of children.

To manage symptoms of gastroesophageal reflux disease (GERD), indigestion, and gastritis, try to eat smaller meals more often instead of large meals. This can help prevent the stomach from becoming too full and causing acid reflux.
Avoid foods and drinks that can irritate your stomach, such as spicy foods, fatty foods, coffee, alcohol, and carbonated drinks. These can worsen your symptoms.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Gastroesophageal Reflux Disease, Indigestion, Gastritis
Drug Category	Prokinetic Agent, Proton Pump Inhibitor
Therapeutic Category	Gastrointestinal Medicine

What is Pentate D Tablet 10 used for?

Pentate D Tablet 10 is used to manage indigestion, gastroesophageal reflux disease (GERD) and gastritis when pantoprazole alone doesn't work well.

How does Pentate D Tablet 10 work?

It contains domperidone, which prevents stomach acid reflux, and pantoprazole, which reduces stomach acid. Together, they provide relief from acid reflux symptoms.

Can Pentate D Tablet 10 cause drowsiness or dizziness?

Yes, it may cause drowsiness or dizziness. Avoid driving or operating machinery until you know how this medicine affects you.

Are there any serious side effects of Pentate D Tablet 10?

Rare but serious side effects include irregular heartbeat, fainting, uncontrollable body movements, enlarged breasts in men, and severe abdominal pain.

Can I take Pentate D Tablet 10 with other medicines?

This medicine may interact with several medications. Always inform your doctor about other medicines you're currently taking before starting this medicine.

Is Pentate D Tablet 10 safe for pregnant women or breastfeeding mothers?

The safety of Pentate D Tablet 10 during pregnancy and lactation hasn't been established. Always consult your doctor if you're pregnant or breastfeeding.

What should I do if I accidentally take too much of the medicine?

Overdosing can cause symptoms like confusion and drowsiness. In case of a suspected overdose, immediately contact emergency medical services.

Last Updated On 13 May. 2025 | 11:19AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Content Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Saniya K Mulla

Medical Content Writer | 6 years

MBBS

Check out Editorial Policy

Manufacturer details

218/19, Midas Sahar Plaza, M V Road, J B Nagar, Mumbai, Maharashtra 400059

Country of origin: INDIA

Expiry on or after: December 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Reddymasu, S. C., Soykan, I., & McCallum, R. W. (2007). Domperidone: review of pharmacology and clinical applications in gastroenterology. The American journal of gastroenterology, 102(9), 2036–2045. https://pubmed.ncbi.nlm.nih.gov/17488253/
PubChem. (n.d.-d). Domperidone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/3151#section=Interactions-and-Pathways
Domperidone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01184
PubChem. (n.d.-e). Pantoprazole. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/4679#section=Toxicity
Pantoprazole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00213
Pantoprazole: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a601246.html

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