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CompositionPause Injection is used to manage excessive bleeding in various conditions. As an antifibrinolytic agent, it helps stabilize blood clots and is beneficial in managing heavy menstrual bleeding, nosebleeds, and bleeding after surgery. This injection is also used in cases of hereditary angioedema and after tooth extraction in hemophilia patients. Consult your doctor for the appropriate dosage and administration before use and inform them about any ongoing medical conditions.
Pause Injection is used to manage excessive bleeding caused by various conditions. It helps control heavy menstrual bleeding, nosebleeds, and bleeding in the eye. It also supports recovery after surgeries like prostate, bladder, or cervical surgery and helps manage bleeding in patients with hereditary angioedema or hemophilia. This injection is essential for controlling bleeding safely and effectively.
Administer Pause Injection following these steps:
Pause Injection is administered intravenously.
Pause Injection may cause nausea, vomiting, and muscle cramps. These side effects are usually mild but may cause discomfort.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pause Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some suggestions for managing common side effects:
Nausea or Vomiting: Try taking Pause Injection with food to lessen this effect.
Muscle cramps: Consider rest and massage as it could help alleviate muscle discomfort.
Pause Injection contains tranexamic acid (500 mg), which works on your body as follows:
Inhibition of Plasminogen Activation: Tranexamic acid inhibits the activation of plasminogen to plasmin. Plasminogen is a substance that gets converted into an enzyme called plasmin.
Stabilisation of Blood Clots: By preventing the conversion of plasminogen into plasmin, tranexamic acid stops plasmin from breaking down fibrin clots - a key component in blood clotting. This helps stabilise blood clots.
Reduction in Bleeding: Tranexamic acid helps reduce bleeding by stabilising blood clots and promoting haemostasis (the stoppage of bleeding). The reduction in bleeding is particularly useful when the bleeding is caused by excessive breakdown of blood clots (fibrinolysis).
Pause Injection is not recommended during pregnancy unless clearly needed. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.
It's important to note that Pause Injection may pass into breast milk. The effects on nursing infants are unknown so it's best to consult your doctor if you're breastfeeding.
There's no specific information about the interaction of Pause Injection with alcohol. However, it's generally a good idea to limit alcohol consumption while using any medicine.
Caution is advised while taking Pause Injection if you have mild to moderate liver impairment. It's best to discuss any liver-related concerns with your doctor before starting this medicine.
If you have a history of kidney problems, it would be wise to consult your doctor before taking Pause Injection. The dosage may need adjustment based on kidney function.
Pause Injection can cause dizziness or visual disturbances that may affect your ability to drive or operate machinery. Be cautious until you know how this medicine affects you.
If you're allergic to tranexamic acid or any other ingredient in Pause Injection, do not use this medicine. Always inform your doctor about any known allergies before starting a new medication.
Pause Injection is meant for adults and should not be given to children without medical supervision. Always consult your doctor before giving any medicine to a child.
Older patients should take Pause Injection under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Pause Injection interacts with the following medicines:
Hormonal Contraceptives: When used alongside Pause Injection, hormonal contraceptives such as levonorgestrel and ethinylestradiol may increase the risk of thromboembolism (blood clots).
Antifibrinolytic Agents: Medicines like aprotinin, when taken with Pause Injection, can enhance the antifibrinolytic effect and potentially increase clotting.
Factor IX Complex Concentrates or Anti-Inhibitor Coagulant Complexes: Medicines such as Bebulin and Feiba may interact with Pause Injection, potentially increasing clot formation.
There are no known food interactions with this injection.
Blood Disorders: If you have blood disorders that cause clotting problems, be cautious because Pause Injection can increase clotting and worsen your condition.
Kidney Disease: The dosage of Pause Injection needs to be adjusted if you have kidney disease, as the medicine can accumulate in your body.
Heart Disease: If you've heart ailments, ensure you inform your doctor as certain heart conditions could be exacerbated by the increased clotting.
The daily dose of Pause Injection should be administered as directed by your doctor. The dosage may vary based on factors such as the severity of your condition and your response to the medicine. For further details regarding dosage, please read the package insert.
An overdose of Pause Injection might cause some common side effects to become more severe, such as nausea or muscle cramps. If you suspect you've had more than your prescribed dosage, consult your doctor.
If you miss a dose of Pause Injection, administer it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.
Avoid direct sunlight and do not freeze the product.
Always keep this medicine out of reach of children.
If you're managing heavy menstrual bleeding, consider increasing your intake of iron-rich foods like spinach and lentils to help compensate for blood loss.
To alleviate nosebleeds, try using a humidifier at home as dry air can cause nasal tissues to dry out and bleed.
| Available Dosage Types | Injection |
| Habit Forming | No |
| Ailment | Menorrhagia, Traumatic Hyphema, Hemophilia |
| Drug Category | Antifibrinolytic Agent |
| Therapeutic Category | Hemostatic Agent |
Pause Injection is primarily used to manage and control excessive bleeding in various medical conditions such as heavy menstrual bleeding, nosebleeds, and after certain surgeries.
Pause Injection contains tranexamic acid which works by inhibiting the breakdown of blood clots. This helps to stabilise blood clots, reduce bleeding, and halt further bleeding.
Yes, Pause Injection can be used to manage bleeding after tooth extraction in patients with haemophilia. It's administered before the procedure and continued as needed afterwards.
Common side effects include nausea, vomiting, diarrhoea, and muscle cramps. Rarely, low blood pressure or blood clots can occur. If you experience any serious side effects, contact your doctor immediately.
Yes, inform your doctor about any allergies, blood disorders, kidney disease, heart disease or history of seizures or stroke before starting with Pause Injection.
Pause Injection is not recommended during pregnancy unless clearly needed. It may pass into breast milk and the effects on nursing infants are unknown. Always consult your doctor first.
Some medications may interact with tranexamic acid in Pause Injection, increasing the risk of complications such as thromboembolism. Always inform your doctor about all medications you are currently taking before starting treatment.
Check out Editorial Policy
U.S. National Library of Medicine. (2021). Tranexamic Acid. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a612021.html
U.S. Food and Drug Administration. (2021). Lysteda (tranexamic acid) Tablets. U.S. Department of Health and Human Services. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019281Orig1s047lbl.pdf
Tranexamic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00302
Website, N. (2024, April 29). Tranexamic acid. nhs.uk. https://www.nhs.uk/medicines/tranexamic-acid/
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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