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Tranexamic Acid

Anti-Fibrinolytic Category

Uses of Tranexamic Acid

Tranexamic Acid is an antifibrinolytic medicine used to prevent and treat excessive bleeding.

Tranexamic Acid is commonly used for:

• Heavy menstrual bleeding: Reduces excessive blood loss during periods.
• Bleeding associated with major trauma: May be given in hospital to reduce bleeding when used promptly and appropriately.
• Bleeding disorders: Manages bleeding associated with conditions that affect normal clot stability.
• Post-operative bleeding: Reduces blood loss during or following selected surgical procedures.
• Bleeding after dental procedures: Helps control bleeding in patients with bleeding disorders undergoing dental treatment.

Side effects of Tranexamic Acid

  • Feeling sick
  • Being sick
  • Diarrhoea 

How Tranexamic Acid works

Tranexamic Acid works by helping blood clots stay stable for longer, reducing bleeding.

When the body forms a blood clot, an enzyme called plasmin naturally breaks it down over time. Tranexamic Acid blocks the action of plasmin, which slows down the breakdown of clots.

This helps stabilise clots and reduce excessive bleeding, including heavy bleeding from the lining of the uterus during periods.

Certified content

Written By

docImg
Dr. Sachin SinghMedical Team Lead & Reviewer| 7 years

MBBS

Reviewed By

Dr. Mandeep Chadha
Dr. Mandeep ChadhaLead Medical Content Reviewer| 12 years

MBBS, DNB (OBGY)

Expert Advice

Dosage Forms Available

  • Tablet and Injection.

Age and Dose Restrictions

  • It is intended for adults and children above one year of age.

Contraindications

  • It is contraindicated in patients with a history of hypersensitivity to Tranexamic Acid and patients with renal insufficiency, currently having blood clots or disease leading to blood clots, consumption coagulopathy, and a history of convulsions.

Other Medications To Avoid With This Medicine

  • Avoid taking other anti-fibrinolytic medicines (aprotinin), thrombolytic medicines (streptokinase), and oral contraceptives (ethinylestradiol). These medications may alter the safety and effectiveness of Tranexamic Acid.

Overdose and Missed Dose

  • Overdose can cause dizziness, headache, nausea, vomiting, diarrhoea, orthostatic symptoms hypotension and convulsions. These symptoms need to be managed as an emergency in a hospital setting. Therefore, strict adherence to the prescribed dose is essential.
  • If you miss a dose of Tranexamic Acid, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Use In Driving And Operating Machinery

  • It does not affect the ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • Caution is advised in pregnancy. It is not recommended during breastfeeding. 

Caution In Other Conditions

  • Caution is advised in older adults and in patients who have had blood in their urine.

Special Dietary & Lifestyle Recommendation

  • Consume a well-balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats.
  • Incorporate iron-rich foods, such as spinach, lentils, lean red meat, and fortified cereals, to support blood production.
  • Limit or avoid foods that can thin the blood or increase bleeding, such as excessive garlic, ginger, turmeric, and omega-3 fatty acid supplements.
  • Follow a low-sodium diet to help maintain optimal blood pressure levels.
  • Limit the intake of processed and packaged foods, often high in sodium.
  • Engage in regular exercise, such as walking or swimming, to help manage blood pressure.
  • Maintain good oral hygiene habits, including regular brushing, flossing, and dental check-ups.
  • Avoid taking alcohol with this medication to avoid the risk of side effects.

Frequently asked questions

It shows its effects within a few hours after administration. The time it takes to stop bleeding varies depending on the individual and the specific condition being treated. 

It is generally considered safe when used as prescribed by a doctor. However, it is contraindicated in patients with deep vein thrombosis, pulmonary embolism, kidney problems, brain haemorrhage, visual defects, and seizures.

It is generally recommended to be taken with food to reduce the risk of stomach upset or irritation. 

It is not known to affect fertility in either males or females. It is an antifibrinolytic medication primarily used to control bleeding, and its mechanism of action does not interfere with fertility or reproductive functions.

It is not known to cause a pulmonary embolism directly.

It is not typically used to treat piles (haemorrhoids).

Terms & Conditions


List of medicines for Tranexamic Acid

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Texakind Tablet 10
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Tyrodin Tablet 10
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Melano Tx Od Tablet 15
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