Met Xl H 50 Tablet 20

Ajanta Pharma Ltd

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Old MRP ₹314

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Composition

Hydrochlorothiazide (12.5 Mg) + Metoprolol Succinate (50 Mg)

Met Xl H 50 Tablet 20 is used to manage high blood pressure (hypertension). It is a combination medicine that belongs to a class of medications known as antihypertensives.

This medicine helps prevent serious cardiovascular problems such as heart attacks and strokes. When your blood pressure remains high for a long time, it puts extra strain on your heart and blood vessels, which can lead to health complications. Early treatment with this medicine can improve survival chances if you have suffered a heart attack.

You should take this medicine as directed by your doctor. Before starting this medicine, inform your doctor about any existing medical conditions and any other medications you are currently taking. If you notice any side effects while using this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for the best results.

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Met Xl H 50 Tablet 20 is used for the following:

Treatment of hypertension
Managing high blood pressure
Prevention of heart attacks
Reducing the risk of serious cardiovascular events
Improving survival after heart attack
Managing blood pressure when single medicines fail
Controlling blood pressure in complex cases

Follow these instructions while taking Met Xl H 50 Tablet 20:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or divide the tablet.
You can take this medicine with or without food.

Met Xl H 50 Tablet 20 is taken orally.

Met Xl H 50 Tablet 20 may have the following common side effects:

Nausea
Fatigue
Diarrhoea
Constipation
Dizziness
Electrolyte imbalance

Managing the Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Met Xl H 50 Tablet 20. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Dizziness: Taking this medicine at bedtime rather than in the morning can help reduce dizziness during your daily activities.
Nausea: Taking this medicine with food can help decrease stomach discomfort.

Met Xl H 50 Tablet 20 contains two active ingredients that work together to lower blood pressure:

Metoprolol succinate (50 mg): This is a beta-blocker that slows down your heart rate and reduces the force of heart muscle contractions. This action decreases the workload on your heart, resulting in lower blood pressure.
Hydrochlorothiazide (12.5 mg): This is a thiazide diuretic that acts on your kidneys to increase the elimination of excess water and electrolytes (salts) from your body. By reducing the volume of fluid in your blood vessels, it helps lower your blood pressure.

Pregnancy

Caution is advised while taking Met Xl H 50 Tablet 20 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Met Xl H 50 Tablet 20 if you are breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Avoid drinking alcohol while taking Met Xl H 50 Tablet 20. Alcohol can enhance the blood pressure-lowering effect of this medicine and may cause excessive dizziness or drowsiness.

Liver

Caution is advised while taking Met Xl H 50 Tablet 20 in case of liver problems. If you have any liver disease, discuss this with your doctor before starting this medicine.

Kidney

Caution is advised before using Met Xl H 50 Tablet 20 if you have a history of kidney problems. Consult your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause dizziness, especially when you stand up quickly. If you feel dizzy, avoid driving or operating heavy machinery until you feel better.

Allergy

Inform your doctor about any allergies you have before taking Met Xl H 50 Tablet 20. If you notice a rash, itching, or swelling after taking this medicine, seek medical help immediately.

Children

Caution is advised while giving Met Xl H 50 Tablet 20 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Met Xl H 50 Tablet 20 under medical supervision as they may be more sensitive to its effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Met Xl H 50 Tablet 20 interacts with the following medicines:

Antihypertensives: Medicines like amlodipine or enalapril may enhance the blood pressure-lowering effect of Met Xl H 50 Tablet 20, potentially causing excessive reduction in blood pressure.
Antidiabetic Medicines: Met Xl H 50 Tablet 20 may affect blood sugar control, potentially altering the effectiveness of metformin or glimepiride. Regular monitoring of blood glucose levels is important.
NSAIDs: Medicines like ibuprofen or diclofenac can reduce the effectiveness of Met Xl H 50 Tablet 20 by interfering with its blood pressure-lowering action.
Cardiac Glycosides: Met Xl H 50 Tablet 20 may interact with digoxin, potentially affecting heart function or causing electrolyte imbalances.

Drug-Food Interactions

Met Xl H 50 Tablet 20 has limited food interactions.

High-Salt Foods: Consuming foods high in sodium may reduce the effectiveness of the hydrochlorothiazide component in Met Xl H 50 Tablet 20.

Drug-Disease Interactions

Met Xl H 50 Tablet 20 interacts with the following diseases:

Asthma: The metoprolol component may worsen breathing difficulties in people with asthma.
Diabetes: This medicine may mask symptoms of low blood sugar and affect blood glucose control.
Kidney disease: The hydrochlorothiazide component may be less effective and potentially harmful in patients with severe kidney problems.
Liver disease: Patients with liver problems may experience increased effects of Met Xl H 50 Tablet 20 due to altered metabolism.

Daily Dose

The daily dose of Met Xl H 50 Tablet 20 should be taken as prescribed by your doctor. The dosage may vary based on your blood pressure levels and how your body responds to the medicine. Follow the prescribed dosage without exceeding it unless your doctor advises otherwise.

Over Dose

Overdosing on Met Xl H 50 Tablet 20 may cause extreme dizziness, unusual tiredness, slow heartbeat, or feeling faint when standing up. It might also lead to increased urination and dehydration. Contact your doctor if you experience these symptoms.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never double the dose to make up for the one you missed.

Store at room temperature (below 30°C).
Keep away from light, heat, and moisture.
Store in the original packaging until ready to use.
Keep out of reach of children.
Do not use this medicine after the expiry date printed on the package.

Reduce your salt intake to help manage high blood pressure (hypertension). Try using herbs and spices instead of salt to flavour your food.
Engage in regular physical activity like brisk walking for at least 30 minutes most days of the week, which helps lower blood pressure naturally and improves the effectiveness of Met Xl H 50 Tablet 20.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, heart attack prevention
Drug Category	Beta-blocker + diuretic
Therapeutic Category	Antihypertensive

How does the Met Xl H 50 Tablet 20 work?

It contains metoprolol succinate, which slows heart rate, and hydrochlorothiazide, which removes excess water from your body. Together they lower blood pressure.

What should I do if I miss a dose?

Take it as soon as you remember. If it is nearly time for your next dose, skip the missed one. Never take a double dose.

Can I stop taking Met Xl H 50 Tablet 20 when my blood pressure normalises?

No, continue taking it as prescribed even if you feel well. Stopping suddenly may worsen your high blood pressure (hypertension).

What side effects might I experience?

Common side effects include dizziness, fatigue, headache, nausea, and increased urination. Most side effects are mild and temporary.

Can I drive after taking Met Xl H 50 Tablet 20?

Be cautious about driving, especially when starting treatment. If you experience dizziness or lightheadedness, avoid driving until these effects subside.

Should I avoid any foods while taking Met Xl H 50 Tablet 20?

Maintain a low-salt diet as recommended by your doctor. Avoid alcohol, as it may enhance the blood pressure-lowering effect and cause dizziness.

What is Met Xl H 50 Tablet 20 used for?

Met Xl H 50 Tablet 20 is used to manage high blood pressure (hypertension). It helps lower blood pressure when a single medicine is not enough to control it effectively.

Last Updated On 12 Jun. 2025 | 7:07AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053

Country of origin: INDIA

Expiry on or after: March 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

DailyMed. (n.d.). Metoprolol succinate extended-release tablet, film coated, extended release. U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=5988bc0d-68dc-47bc-819d-2709572042ce (Accessed 1 April 2025)
U.S. Food and Drug Administration. (2018). Metoprolol succinate extended-release capsules, for oral use [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210428s000lblReplacement.pdf (Accessed 1 April 2025)
DrugBank. (n.d.). Hydrochlorothiazide. https://go.drugbank.com/drugs/DB00999 (Accessed 1 April 2025)
Herman, L. L., Weber, P., & Bashir, K. (2023, November 12). Hydrochlorothiazide. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK430766/
Hainer, J. W., & Sugg, J. (2007). Metoprolol succinate extended release/hydrochlorothiazide combination tablets. Vascular Health and Risk Management, 3(3), 279–288. https://pmc.ncbi.nlm.nih.gov/articles/PMC2293963/

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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