Met Xl H 25 Tablet 20

Ajanta Pharma Ltd

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MRP ~~₹207.19~~

₹178.18

₹10.36/Units

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Prescription required for this medicine

Store Below 30° C

Composition

Hydrochlorothiazide (12.5 Mg) + Metoprolol Succinate (25 Mg)

Met Xl H 25 Tablet 20 is used to manage high blood pressure. It is a combination antihypertensive medicine containing hydrochlorothiazide and metoprolol succinate.

This medicine helps lower and control blood pressure, including cases not responding well to a single medicine. It also supports blood pressure control in elderly patients, including those with kidney concerns.

Reducing salt and following an activity plan advised by your doctor can support heart and blood pressure management alongside this medicine.

Before starting, tell your doctor about your medical conditions and allergies. Tell the doctor about all other medicines, supplements or herbal products you take. Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding. Report persistent or serious side effects to your doctor. Do not stop taking or using the medicine unless your doctor advises you to do so.

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Met Xl H 25 Tablet 20 is used to manage high blood pressure.

Uses of Met Xl H 25 Tablet 20 are:

High Blood Pressure: Helps lower and control blood pressure, including cases not responding well to a single medicine.
Elderly Blood Pressure Management: Supports blood pressure control in elderly patients, including those with kidney concerns.

Follow these instructions while taking Met Xl H 25 Tablet 20 :

Swallow the tablet whole with a full glass of water.
Do not crush, chew, or break the tablet as this may affect its extended-release properties.
Take this medicine at the same time each day to maintain consistent levels in your body.
You may take this medicine with or without food.
Continue taking this medicine even if you feel well unless your doctor advises otherwise.
Consult your doctor if you have any questions about how to take this medicine.

Met Xl H 25 Tablet 20 is taken orally.

Met Xl H 25 Tablet 20 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.

A few common side effects of Met Xl H 25 Tablet 20:

Nervous system: dizziness, headache, fatigue.
Ear: slow heartbeat.
Digestive: nausea.
Decreased blood potassium levels: this occurs when the medicine causes your body to lose too much potassium through urine.
Increased uric acid levels: this means there is too much uric acid in your blood, which might sometimes lead to joint pain.

If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so.

Management Of Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Met Xl H 25 Tablet 20. However, if you experience any serious side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking Met Xl H 25 Tablet 20 with food can help reduce feelings of sickness.
Dizziness: Consider taking this medicine at bedtime to minimise the impact of dizziness on your daily activities.

Met Xl H 25 Tablet 20 contains two active ingredients:

Metoprolol succinate (25 mg): This selective beta-1 receptor blocker works by blocking the action of certain natural substances like epinephrine (adrenaline) on your heart and blood vessels. This action results in a slower heartbeat and relaxation of blood vessels, thereby improving blood flow and decreasing blood pressure.
Hydrochlorothiazide (12.5 mg): This component is a thiazide diuretic that increases urine production by helping the kidneys eliminate excess salt (sodium) and water from the body. This process decreases blood volume, which subsequently lowers blood pressure.

Pregnancy

Met Xl H 25 Tablet 20 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking Met Xl H 25 Tablet 20 if you are breastfeeding. Small amounts of the medicine may pass into breast milk. It is best to consult your doctor before taking this medicine.

Alcohol

Caution is advised when consuming alcohol while taking Met Xl H 25 Tablet 20. Alcohol might increase the blood pressure-lowering effect of this medicine and cause dizziness or light-headedness.

Liver

This medicine is often prescribed for older patients, who may be more susceptible to liver health issues. It is advisable to discuss liver-related concerns with your doctor before starting treatment with Met Xl H 25 Tablet 20. They will evaluate whether this medicine is suitable.

Kidney

Consult your doctor before using Met Xl H 25 Tablet 20 if you have kidney problems. Older patients often have reduced kidney function, which may affect how this medicine works in your body.

Use In Driving And Operating Machinery

Met Xl H 25 Tablet 20 may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you feel better.

Allergy

If you have any known allergies to metoprolol, hydrochlorothiazide, or similar medicines, inform your doctor before taking Met Xl H 25 Tablet 20. Allergic reactions may include rash, itching, or swelling.

Children

Caution is advised while giving Met Xl H 25 Tablet 20 to children under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Met Xl H 25 Tablet 20 should be taken under medical supervision, as older patients may be more sensitive to its effects. Your doctor might monitor your kidney function and electrolyte levels regularly. Caution is particularly important if you have other health conditions or are taking additional medicines.

Drug-Drug Interactions

Met Xl H 25 Tablet 20 interacts with the following medicines:

Antidiabetic medicines: Met Xl H 25 Tablet 20 may alter insulin and metformin effects, potentially masking symptoms of low blood sugar (hypoglycaemia).
NSAIDs: Medicines like ibuprofen and naproxen may reduce the blood pressure-lowering effect of Met Xl H 25 Tablet 20.
Cardiac medicines: When taken with Met Xl H 25 Tablet 20, Digoxin may increase the risk of slow heartbeat (bradycardia).
Antihypertensive medicines: Other blood pressure medicines, such as amlodipine or lisinopril, may enhance the blood pressure-lowering effect of Met Xl H 25 Tablet 20.
Cholesterol-lowering medicines: Colestipol may decrease the absorption of hydrochlorothiazide in Met Xl H 25 Tablet 20.

Drug-Food Interactions

Met Xl H 25 Tablet 20 has minimal food interactions. You can take it with or without food, preferably at the same time each day to maintain consistent blood levels.

Drug-Disease Interactions

Met Xl H 25 Tablet 20 interacts with the following diseases:

Asthma and breathing disorders: The Metoprolol component may worsen breathing difficulties in elderly patients with respiratory conditions.
Diabetes: This may mask symptoms of low blood sugar and affect blood glucose control.
Gout: The Hydrochlorothiazide component can increase uric acid levels, potentially worsening gout symptoms.
Liver disease: Reduced liver function may affect how your body processes Met Xl H 25 Tablet 20.
Kidney disease: May require dose adjustment as kidney function affects medicine clearance.

Daily Dose

The daily dose of Met Xl H 25 Tablet 20 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as the severity of your condition and your response to treatment. Always follow the prescribed dosage schedule.

Over Dose

Taking more than the prescribed dose of Met Xl H 25 Tablet 20 may cause dizziness, extreme fatigue, unusually slow heartbeat, increased urination, and confusion. Older adults may experience more severe effects like fainting or dehydration due to excessive fluid loss.

Missed Dose

If you forget to take your Met Xl H 25 Tablet 20, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage without consulting your doctor.

Store Met Xl H 25 Tablet 20 at room temperature (below 30°C).
Keep the medicine in a dry place away from direct sunlight and moisture.
Do not store it in the bathroom.
Keep Met Xl H 25 Tablet 20 out of reach of children and pets.
Check the expiry date and do not use the medicine after this date.

Reduce your salt intake, as high sodium consumption can worsen high blood pressure (hypertension). Try using herbs and spices instead of salt to flavour your food.
Maintain regular physical activity appropriate for your age and ability, such as gentle walking for 20-30 minutes daily, which helps lower blood pressure naturally.

Fact Box

Dosage Forms Available	Tablet Er
Habit Forming	No
Ailment	Hypertension, stroke risk
Drug Category	Beta-blocker and diuretic
Therapeutic Category	Antihypertensive

How does Met Xl H 25 Tablet 20 work?

Met Xl H 25 Tablet 20 contains two medicines: metoprolol slows your heart rate and relaxes blood vessels, while hydrochlorothiazide removes excess water from your body. Together, they effectively lower blood pressure.

Is Met Xl H 25 Tablet 20 safe for elderly patients?

This medicine is specifically formulated for older adults, but your doctor should monitor your kidney function regularly. Elderly patients may need careful dosage adjustment to prevent side effects.

What are the common side effects of Met Xl H 25 Tablet 20?

Common side effects include dizziness, fatigue, headache, slower heartbeat, and sometimes nausea. Most side effects are mild and improve as your body adjusts to the medicine.

Should I take Met Xl H 25 Tablet 20 with food?

You can take this medicine with or without food, but it's best to take it at the same time each day. Swallow the tablet whole with water—never crush or chew it.

What should I do if I miss a dose?

If you forget to take your dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

Can I stop taking Met Xl H 25 Tablet 20 once my blood pressure normalises?

Don't stop taking this medicine without consulting your doctor, even if your readings improve. Sudden discontinuation can worsen your condition or cause withdrawal symptoms.

Can Met Xl H 25 Tablet 20 affect my blood sugar levels?

Yes, this medicine may affect blood glucose levels, especially if you have diabetes. Regular monitoring is important; your doctor may need to adjust your diabetes medicines.

Last Updated On 16 Sep. 2026 | 6:31AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 14 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 10 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

54, Sir Mathuradas Vasanji Rd, Hanuman Nagar, Andheri East, Mumbai, Maharashtra 400053

Country of origin: INDIA

Expiry on or after: January 2027

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

U.S. Food and Drug Administration. (n.d.). Product-specific guidance: Metoprolol succinate. U.S. Department of Health & Human Services. Retrieved 1 April 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/PSG_019962.pdf
Hydrochlorothiazide - StatPearls - NCBI bookshelf. (2023, July 17). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK430766/
Hydrochlorothiazide. (2025, May 2). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00999
Metoprolol: MedlinePlus drug information. (2023, September 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682864.html

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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CIN: U62099MH2019PTC320566

Telephone:09240250346

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