Listril Plus Tablet 15

Torrent Pharmaceuticals Ltd.

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STRIP of 15 Units

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MRP ~~₹243.75~~

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Composition

Hydrochlorothiazide (12.5 Mg) + Lisinopril (5 Mg)

Listril Plus Tablet 15 is used to manage hypertension (high blood pressure). It is a combination medicine that belongs to a class of medications known as antihypertensives.

Additionally, this medicine helps prevent fluid retention (oedema) that may occur due to conditions affecting the liver, kidneys, or lungs. By controlling high blood pressure, it also helps reduce the risk of heart attacks and strokes, which are common complications associated with untreated hypertension.

The medicine should be taken orally as prescribed by your doctor. It is important to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects while taking this medicine, notify your doctor promptly. Continue taking the medicine for the duration prescribed by your doctor to achieve optimal results.

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Listril Plus Tablet 15 is used for the following:

Treatment of high blood pressure
Management of fluid retention
Prevention of heart attacks
Reduction of stroke risk
Control of hypertension in kidney patients
Management of oedema in liver conditions
Reduction of excess fluid in lung disorders
Prevention of hypertension-related complications

Follow these instructions while taking Listril Plus Tablet 15:

Swallow the tablet whole with a glass of water.
Take this medicine at the same time each day, preferably in the morning.
You can take it with or without food.
Do not break, crush, or chew the tablet.
Continue taking this medicine even if you feel well.
Consult your doctor if you have questions about using this medicine.

Listril Plus Tablet 15 is taken orally.

Listril Plus Tablet 15 may have the following common side effects:

Dizziness
Cough
Nausea
Headache
Low blood pressure: This occurs when your blood pressure drops below normal levels, which may make you feel faint or lightheaded.
Electrolyte imbalances: This refers to changes in the levels of important minerals in your blood, such as sodium and potassium, which help your body function properly.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Listril Plus Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Dizziness: Try taking Listril Plus Tablet 15 in the morning to reduce dizziness during your daily activities.
Nausea: Taking this medicine with food can help reduce stomach upset and nausea.

Listril Plus Tablet 15 contains two active ingredients:

Lisinopril (5 mg): This is an angiotensin-converting enzyme (ACE) inhibitor that works by blocking an enzyme in your body that narrows blood vessels. By preventing this narrowing, lisinopril allows your blood vessels to relax and widen, which lowers blood pressure.
Hydrochlorothiazide (12.5 mg): This is a thiazide diuretic or "water pill" that increases the amount of urine you produce. It helps your body get rid of extra salt and water through urination, which reduces the volume of blood in your vessels and lowers blood pressure.

Pregnancy

Listril Plus Tablet 15 is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine, as it may cause potential birth defects.

Breastfeeding

Alcohol

Avoid alcohol while taking Listril Plus Tablet 15. Drinking alcohol with this medicine may increase the risk of dizziness and lower your blood pressure too much.

Liver

Caution is advised while taking Listril Plus Tablet 15 if you have liver problems. This medicine should be used carefully if you have mild to moderate liver impairment. Discuss any liver conditions with your doctor before starting treatment.

Kidney

Caution is advised before using Listril Plus Tablet 15 if you have a history of kidney problems. Your doctor may need to adjust your dose based on your kidney function, as this medicine affects how your kidneys work.

Using Machines & Driving

This medicine may cause dizziness, especially when you first start taking it. Be careful when driving or using machines until you know how Listril Plus Tablet 15 affects you. Rising slowly from sitting or lying positions can help prevent dizziness.

Allergy

Do not take Listril Plus Tablet 15 if you are allergic to lisinopril, hydrochlorothiazide, or similar medicines like ACE inhibitors or sulfonamide-derived medications. Tell your doctor about any past allergic reactions to medicines.

Children

Caution is advised while giving Listril Plus Tablet 15 to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Listril Plus Tablet 15 under medical supervision, as they may be more sensitive to its effects. Your doctor may start with a lower dose if you are elderly, especially if you have kidney issues or are taking other medicines.

Drug-Drug Interactions

Listril Plus Tablet 15 interacts with the following medicines:

Diuretics: Medicines like furosemide may increase the risk of dehydration and low blood pressure when taken with Listril Plus Tablet 15.
Potassium supplements: Products containing potassium can increase potassium levels in your blood when combined with Listril Plus Tablet 15, potentially causing heart rhythm problems.
NSAIDs: Medicines like ibuprofen and naproxen may reduce the blood pressure-lowering effects of Listril Plus Tablet 15 and potentially affect kidney function.
Antidiabetic medicines: Insulin and oral hypoglycaemic agents may need dosage adjustments, as Listril Plus Tablet 15 can affect blood sugar levels.
Psychiatric medications: Listril Plus Tablet 15 may increase lithium levels in your blood, potentially leading to lithium toxicity.

Drug-Food Interactions

Listril Plus Tablet 15 has minimal food interactions. Taking it with food helps reduce stomach upset.

High-salt foods: Consuming excessive salt may reduce the effectiveness of Listril Plus Tablet 15 in controlling blood pressure.

Drug-Disease Interactions

Listril Plus Tablet 15 interacts with the following diseases:

Kidney disease: This medicine may worsen kidney function in patients with existing kidney problems.
Liver disease: Patients with liver impairment should use Listril Plus Tablet 15 cautiously, as it may affect liver function.
Diabetes: Listril Plus Tablet 15 might affect blood sugar control, requiring closer monitoring of glucose levels.
Gout: The hydrochlorothiazide component can increase uric acid levels, potentially triggering gout attacks.

Daily Dose

The daily dose of Listril Plus Tablet 15 should be taken as prescribed by your doctor. The dosage may vary based on your blood pressure readings and how well you respond to treatment. Always follow the prescribed dosage and never adjust it without consulting your doctor.

Over Dose

An overdose of Listril Plus Tablet 15 may cause dizziness, weakness, excessive urination, dehydration, or unusually low blood pressure. You might feel faint when standing up. Contact your doctor if you experience these symptoms after taking too much.

Missed Dose

If you forget to take this medicine, take it as soon as you remember. If it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose to make up for a missed one.

Store Listril Plus Tablet 15 at room temperature (not exceeding 25°C).
Keep away from moisture, heat, and direct light.
Store it in the original packaging to protect it from environmental exposure.
Keep out of reach of children.
Do not use after the expiry date printed on the package.

Reduce salt intake: Limiting sodium in your diet helps manage high blood pressure. Try flavouring foods with herbs and spices instead of salt, and avoid processed foods, which often contain hidden sodium.
Regular physical activity: Aim for at least 30 minutes of moderate exercise most days of the week. Activities like brisk walking, swimming, or cycling can help lower blood pressure naturally.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, fluid retention
Drug Category	ACE inhibitor + diuretic
Therapeutic Category	Antihypertensive

What should I do if I miss a dose of Listril Plus Tablet 15?

Take it as soon as you remember, unless it's nearly time for your next dose. Never take a double dose to make up for a missed one.

Can I stop taking Listril Plus Tablet 15 if my blood pressure returns to normal?

No, don't stop taking this medicine without consulting your doctor. Stopping suddenly can cause your blood pressure to rise dangerously.

How long does Listril Plus Tablet 15 take to work?

The medicine begins working within hours, but full blood pressure control may take 2-4 weeks of regular use.

Can I drink alcohol while taking Listril Plus Tablet 15?

It's best to avoid alcohol, as it may increase dizziness and lightheadedness, making side effects worse and reducing the medicine's effectiveness.

What foods should I be careful with while taking Listril Plus Tablet 15?

Be cautious with high-potassium foods like bananas and oranges. The medicine can affect your body's potassium levels.

Is it safe to drive after taking Listril Plus Tablet 15?

You may feel dizzy initially. Avoid driving or operating machinery until you know how this medicine affects you.

What are the signs of an allergic reaction to Listril Plus Tablet 15?

Watch for swelling of the face, lips or tongue, difficulty breathing, severe dizziness, or rash. Seek immediate medical help if these occur.

Last Updated On 12 Jun. 2025 | 4:51PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Torrent House, Off. Ashram Road, Ahmedabad - 380009, Gujarat, India

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Hydrochlorothiazide: MedlinePlus drug information. (2021, February 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682571.html
Lisinopril: MedlinePlus drug information. (2021, February 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a692051.html
U.S. Food and Drug Administration. (2012, October 31). Approval letter: NDA 20-818/S-051. https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2012/020818s051ltr.pdf
U.S. Food and Drug Administration. (2011, December). Label: NDA 19-558/S-054. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019558Orig1s054Lbl_REPLACEMENTS.pdf

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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