Lexicam Tablet 10

Lexicam Tablet may interact with the following medicines:

• Anticoagulants and antiplatelet medicines (e.g., warfarin, heparin and clopidogrel): Lornoxicam may increase the risk of bleeding by affecting platelet function and irritating the gastrointestinal lining. Taking these medicines together may increase the risk of gastrointestinal bleeding and requires careful medical supervision.
• Other NSAIDs (e.g., ibuprofen, diclofenac and naproxen): Taking Lexicam Tablet with other NSAIDs may increase the risk of stomach ulcers, gastrointestinal bleeding and kidney damage. Combining these medicines generally provides little additional benefit and should be avoided unless specifically advised by a doctor.
• Corticosteroids (e.g., prednisolone and dexamethasone): Concurrent use of corticosteroids and lornoxicam may increase the risk of gastrointestinal irritation, ulcers and bleeding. Patients taking both medicines may require additional monitoring and protective treatment as recommended by their doctor.
• Selective serotonin reuptake inhibitors (e.g., fluoxetine and sertraline): These antidepressants may affect platelet function, while lornoxicam can damage the gastrointestinal lining. Their combined use may increase the risk of gastrointestinal bleeding, particularly in patients with a history of stomach ulcers.
• ACE inhibitors, angiotensin receptor blockers and diuretics (e.g., enalapril, losartan and furosemide): Lornoxicam may reduce the blood pressure-lowering effects of certain antihypertensive medicines and decrease the effectiveness of diuretics. Combining these medicines may also increase the risk of kidney impairment, particularly in older or dehydrated patients.
• Methotrexate: Lornoxicam may reduce the renal elimination of methotrexate, potentially increasing its concentration in the blood. This may increase the risk of methotrexate-related toxicity, including bone marrow suppression and kidney damage.
• Lithium: Lornoxicam may reduce the elimination of lithium through the kidneys, leading to increased lithium concentrations in the blood. This may increase the risk of lithium toxicity, which can cause tremors, confusion, vomiting and impaired coordination.
• Cyclosporine and tacrolimus: These immunosuppressants can affect kidney function, and concurrent use with lornoxicam may increase the risk of kidney damage. Patients receiving these combinations may require regular monitoring of kidney function.

None

Lexicam Tablet may interact with the following conditions:

• Peptic Ulcers or Gastrointestinal Bleeding: Lornoxicam reduces the production of protective prostaglandins in the stomach, which may increase the risk of ulcers and gastrointestinal bleeding. Patients with active ulcers or gastrointestinal bleeding should avoid this medicine, as it may worsen their condition.
• Heart Disease or High Blood Pressure: NSAIDs may increase blood pressure, cause fluid retention and increase cardiovascular risk.
• Asthma Associated With NSAID Sensitivity: Lornoxicam may trigger bronchospasm or allergic reactions in patients who have previously experienced asthma attacks after taking aspirin or other NSAIDs. Such patients should avoid this medicine because it may cause severe breathing difficulties.
• Bleeding Disorders: Lornoxicam may impair platelet function and increase the risk of bleeding in patients with existing bleeding disorders. Its use may worsen bleeding complications, particularly in individuals with clotting abnormalities or those receiving anticoagulant treatment.

The dose and duration of Lexicam Tablet depend on the severity of pain, underlying condition and individual response to treatment.  Do not exceed the prescribed dose without consulting your doctor.

An overdose may cause nausea, vomiting, abdominal pain, dizziness, gastrointestinal bleeding, kidney injury or severe liver damage due to paracetamol. Seek immediate medical attention if an overdose is suspected, even if symptoms are initially mild.

If you miss a dose, take it when remembered unless it is nearly time for the next scheduled dose. Skip the missed dose if the next one is due soon. Do not take a double dose.