Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections

Biocon Ltd

Cartridge of 5 UNITS

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MRP ~~₹1072.05~~

₹857.64

₹214.41/UNITS

20% off

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Prescription required for this medicine

Store in refrigerator or (2^o - 8^o C) Do Not Freeze

Composition

Human Insulin/soluble Insulin (100 Iu) + M Cresol (0.16 %) + Phenols (0.065 %)

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections is used to manage diabetes mellitus types I and II as part of a comprehensive treatment programme. This medicine belongs to the class of medications known as antidiabetic agents.

This insulin formulation helps control blood glucose levels in patients with diabetes. It works by facilitating the uptake of glucose by cells, particularly in muscle and fat tissues, while also inhibiting glucose production by the liver, thereby maintaining appropriate blood sugar levels throughout the day.

You should administer this medicine subcutaneously as directed by your doctor. It is important to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you notice any side effects whilst using this medicine, notify your doctor promptly. Continue using the medicine for the duration your doctor prescribes for optimal results.

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Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections is used for the following:

Treatment of type 1 diabetes mellitus
Management of type 2 diabetes mellitus
Controlling blood glucose levels
Preventing diabetic complications
Supporting comprehensive diabetes treatment programmes
Regulating glucose metabolism in diabetic patients
Maintaining glycaemic control in diabetes
Supplementing insulin in insulin-deficient states
Balancing blood sugar with dual-action insulin formulation
Providing both immediate and sustained glucose control

Follow these instructions while using Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections:

Administer subcutaneously as directed by your doctor.
Rotate injection sites with each dose to prevent tissue damage.
Consult your doctor for personalised advice on using this medicine.

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections is administered subcutaneously.

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections may have the following common side effects:

Hypoglycaemia: This occurs when your blood sugar drops too low, causing symptoms like sweating, dizziness, palpitations, headache, anxiety, hunger, confusion, and tremors.
Injection site reactions: You may experience pain, itching or redness when you inject the insulin.
Weight gain
Allergic reactions
Hypokalaemia: This means low potassium levels in your blood, which can affect how your muscles and nerves work.
Lipodystrophy: This refers to changes in fat tissue under the skin at injection sites, causing lumps, pits, or thickened areas.

Managing the Side Effects:

Most side effects are temporary and generally harmless and are resolved by discontinuing the use of Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Hypoglycemia: Administer this medicine 30 minutes before meals to help maintain proper blood sugar levels.
Injection site reactions: Rotate your injection sites regularly to reduce the risk of skin irritation and tissue changes.

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections contains Human Insulin/soluble Insulin (100 IU) and M Cresol (0.16 %), which works in the following manner:

Cellular Glucose Uptake: Human insulin facilitates the movement of glucose from the bloodstream into muscle and fat cells, reducing blood glucose levels.
Hepatic Glucose Suppression: It inhibits glucose production by the liver (hepatic glucose output), preventing additional glucose from entering the bloodstream.
Protein Synthesis Enhancement: The insulin promotes protein synthesis in the body, supporting tissue growth and repair.
Lipolysis Inhibition: It suppresses the breakdown of fats in adipose tissue, helping to regulate energy metabolism.

Pregnancy

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections can be administered during pregnancy if clinically needed. Due to hormonal changes, your insulin requirements may change throughout pregnancy. Regular blood glucose monitoring is important if you are pregnant. Consult your doctor, as dose adjustments may be necessary.

Breastfeeding

This medicine is safe to use during breastfeeding. If you are a nursing mother, monitoring your baby for signs of low blood sugar (hypoglycaemia) is important. Your insulin needs may change during this period, so regular check-ups with your doctor are advisable.

Alcohol

Caution is advised when consuming alcohol while using Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections. Alcohol can increase the risk of hypoglycaemia (low blood sugar) and may affect how well you can recognise its symptoms. If you drink, do so in moderation and always with a meal.

Liver

Caution is advised while administering this medicine if you have liver problems. Liver impairment may reduce your insulin requirements and increase the risk of hypoglycaemia (low blood sugar). Your doctor may need to adjust your dose based on your liver function.

Kidney

Caution is advised when administering this medicine if you have kidney problems. Kidney impairment can reduce your insulin requirements and may increase the risk of hypoglycaemia (low blood sugar). Your doctor might need to monitor your kidney function and adjust your dose accordingly.

Using Machines & Driving

Hypoglycaemia (low blood sugar) may reduce your ability to concentrate and react, which can be risky when driving or operating machinery. Be aware of hypoglycaemia symptoms and check your blood sugar before driving or using machines.

Allergy

If you have a known hypersensitivity to human insulin or any of the ingredients in Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections, this medicine is contraindicated for you. Allergic reactions may include rash, itching, or, in rare cases, more severe symptoms. Seek medical help immediately if you notice any allergic response

Children

Caution is advised when administering Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections to children. While insulin is used to manage diabetes in children, dosing needs careful adjustment based on the child's age, weight, and blood glucose levels. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should use Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections under medical supervision as they may be more susceptible to hypoglycaemia (low blood sugar). Caution is particularly important if you have liver or kidney issues or are taking other medicines. Your doctor will guide your treatment based on your overall health status.

Drug-Drug Interactions

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections interacts with the following medicines:

Oral antidiabetic agents: Medicines like metformin or glimepiride can enhance the blood glucose-lowering effect of Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections, potentially causing hypoglycaemia.
Beta-blockers: Medicines such as propranolol or atenolol may mask the warning signs of low blood sugar and prolong the hypoglycaemic effect of Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections.
ACE inhibitors: Medicines like enalapril or lisinopril can increase the risk of hypoglycaemia when used together with Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections.
Corticosteroids: Medicines such as prednisolone or dexamethasone may decrease the effectiveness of Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections by raising blood glucose levels.
Thyroid hormones: Medicines like levothyroxine can reduce the hypoglycaemic effect of Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections, requiring closer blood sugar monitoring.

Drug-Disease Interactions

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections interacts with the following diseases:

Renal impairment: Patients with kidney problems may need reduced insulin doses as the medicine's effect can be prolonged, increasing hypoglycaemia risk.
Hepatic impairment: Liver disease can reduce insulin requirements and affect blood glucose control, requiring careful monitoring.
Hypoglycaemia: Existing low blood sugar is a contraindication for Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections administration.
Hypokalemia: Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections can worsen low potassium levels by shifting potassium into cells.

Daily Dose

The daily dose of Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections should be administered as prescribed by your doctor. Your dosage may change based on your blood glucose levels, physical activity, meal patterns, and overall health. Always follow the prescribed regimen without making changes on your own.

Over Dose

Taking too much this medicine may cause hypoglycaemia (low blood sugar). You might experience sweating, dizziness, hunger, headache, anxiety, confusion, or trembling. These symptoms can progress if not addressed. Monitor your blood glucose carefully when adjusting doses.

Missed Dose

If you forget to administer Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and resume your regular schedule. Never increase your dosage to make up for missed doses without consulting your doctor.

Store unused this medicine in a refrigerator between 2°C to 8°C.
Protect from light and never freeze the pen.
Keep all medicines out of reach of children.
Check the expiry date before use and discard if expired.

Monitor your carbohydrate intake at each meal and maintain consistency in your eating schedule to help keep your blood glucose levels stable.
Include regular physical activity in your daily routine as exercise helps your body use insulin more effectively and can lower your blood glucose levels.

Fact Box

Available Dosage Types	Injection
Habit Forming	No
Ailment	Diabetes mellitus type I, Diabetes mellitus type II
Drug Category	Blood glucose regulator
Therapeutic Category	Anti-diabetic medicine

How does Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections work in the body?

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections helps lower blood glucose by enabling your cells to absorb sugar, especially in muscles and fat. It also reduces glucose production in your liver.

When should I administer Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections?

This medicine is typically administered 30 minutes before meals. The timing helps match insulin action with food digestion for better glucose control.

What are the signs of low blood sugar with Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections?

Low blood sugar (hypoglycaemia) symptoms include sweating, dizziness, headache, hunger, confusion, trembling hands, and feeling anxious. Always keep glucose tablets handy.

How should I store my Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections?

Unused pens should be refrigerated between 2°C and 8°C.

Why is it important to rotate injection sites?

Rotating injection sites prevents lipodystrophy (lumpy skin changes), which can affect how insulin is absorbed. Use different spots within the same general area.

Can I use Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections during pregnancy?

Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections can be used during pregnancy if needed. However, insulin requirements often change throughout pregnancy, so regular monitoring is essential.

What medicines might affect how Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections works?

Several medicines can alter Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections's effectiveness. Beta-blockers may mask hypoglycaemia symptoms, while corticosteroids can increase blood glucose levels. Always inform your doctor about all medications.

Last Updated On 12 Sep. 2025 | 11:30AM (IST)

Certified Content

Written by

Dr. Nikhil Ambatkar

Medical Content Reviewer | 7 years

Ph.D, M.Tech, B.Tech

Reviewed by

Dr. Betina Chandolia

Lead Medical Content Reviewer | 10 years

BDS, MDS, PGCCL, PGDMH

Check out Editorial Policy

Manufacturer details

20th K.M. Hosur Road, Electronics City, , Bengaluru, Karnataka, 560100

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (n.d.). Insulin regular. U.S. National Library of Medicine. Retrieved 1 April 2025, from https://medlineplus.gov/druginfo/meds/a682611.html
U.S. Food and Drug Administration. (2019, August). Insugen N Refil 100iu Cartridges 3ml Pack Of 5 Injections (insulin injection) prescribing information. https://www.fda.gov/media/130840/download
Human insulin - StatPearls - NCBI bookshelf. (2023, August 28). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK545190/
Insulin human. (2025, May 2). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00030

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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Telephone:09240250346

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