Glimisave M3 850 Tablet Pr 15

Eris Lifesciences Ltd

Strip of 15 Units

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Composition

Glimepiride (3 Mg) + Metformin (850 Mg)

Glimisave M3 850 Tablet Pr 15 is used to manage type 2 diabetes mellitus in adults when diet, exercise, and single-agent therapy fail to adequately control blood glucose levels. It is a combination medicine that belongs to the class of oral antidiabetic medications.

This medicine helps regulate blood glucose levels in patients with type 2 diabetes. It is particularly beneficial when a single medicine alone is not providing adequate control of high blood sugar levels. The combination approach addresses insulin dysfunction through complementary mechanisms for better glycaemic control.

You should take this medicine as directed by your doctor. Before starting this medicine, inform your doctor about any pre-existing conditions you have or any other medicines you are currently taking. If you notice any side effects while using this medicine, notify your doctor immediately. Continue taking the medicine for the full duration prescribed by your doctor for optimal results.

Glimisave M3 850 Tablet Pr 15 is used for the following:

Managing type 2 diabetes mellitus in adults
Controlling high blood glucose levels
Regulating blood sugar when diet and exercise fail
Improving glycaemic control in diabetic patients
Enhancing insulin sensitivity in type 2 diabetes
Complementing lifestyle modifications for diabetes management
Addressing insulin resistance in diabetic patients

Follow these instructions while taking Glimisave M3 850 Tablet Pr 15:

Swallow the tablet whole with a glass of water.
Do not crush, chew, or split the tablet.
Ideally, take this medicine with meals.

Glimisave M3 850 Tablet Pr 15 is taken orally.

Glimisave M3 850 Tablet Pr 15 may have the following common side effects:

Hypoglycaemia: Abnormally low blood sugar levels, with symptoms like sweating, tremors, dizziness, and headache
Nausea
Vomiting
Diarrhoea
Abdominal pain
Metallic taste in the mouth

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Glimisave M3 850 Tablet Pr 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Taking Glimisave M3 850 Tablet Pr 15 with meals can help reduce feelings of sickness.
Metallic taste: Having this medicine during or immediately after meals may help minimise the metallic taste sensation.

Glimisave M3 850 Tablet Pr 15 contains two active ingredients:

Glimepiride (3 mg): This component belongs to the sulfonylurea class of medicines and works by stimulating the pancreatic beta cells to secrete more insulin, helping to lower blood glucose levels.
Metformin (850 mg): As a biguanide, metformin reduces the amount of glucose produced by the liver (hepatic glucose production). It also decreases intestinal glucose absorption and improves insulin sensitivity in body tissues, allowing your cells to respond better to insulin.

Pregnancy

Caution is advised while taking Glimisave M3 850 Tablet Pr 15 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised while taking Glimisave M3 850 Tablet Pr 15 during breastfeeding. It is best to consult your doctor before taking this medicine.

Alcohol

Avoid alcohol when taking Glimisave M3 850 Tablet Pr 15. Alcohol increases your risk of low blood sugar (hypoglycaemia) and can raise the chance of a rare but serious condition called lactic acidosis, which affects how your body processes energy.

Liver

Caution is advised while taking Glimisave M3 850 Tablet Pr 15 in case of mild to moderate liver impairment. It is contraindicated for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before using Glimisave M3 850 Tablet Pr 15 if you have a history of any kidney problems. Your doctor may need to adjust your dosage if you have kidney issues, as this medicine is eliminated through the kidneys.

Using Machines & Driving

Exercise caution when driving or operating machinery while taking Glimisave M3 850 Tablet Pr 15. Low blood sugar (hypoglycaemia) may cause dizziness, blurred vision, or difficulty concentrating, which could affect your ability to drive safely.

Allergy

If you have any known allergies to glimepiride, metformin, or other similar medicines like sulphonylureas, inform your doctor before taking Glimisave M3 850 Tablet Pr 15.

Children

Glimisave M3 850 Tablet Pr 15 is contraindicated for children under 18 years of age. This medicine is specifically designed for managing type 2 diabetes in adults.

Older Patients

Older patients should take Glimisave M3 850 Tablet Pr 15 under medical supervision as they may be more susceptible to its side effects, particularly hypoglycaemia. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Glimisave M3 850 Tablet Pr 15 interacts with the following medicines:

NSAIDs: Medicines like ibuprofen and diclofenac may reduce glucose control when taken with Glimisave M3 850 Tablet Pr 15.
Beta-Blockers: Medicines such as propranolol and atenolol can increase the risk of hypoglycemia (low blood sugar) when combined with glimepiride.
ACE Inhibitors: Medications like enalapril and ramipril may enhance the blood glucose-lowering effect, potentially causing hypoglycaemia.
Cationic Medicines: Medications such as amiloride, digoxin, and morphine may compete with metformin for renal tubular secretion, affecting its elimination.
Corticosteroids: Medicines like prednisolone and dexamethasone can diminish glucose control when taken alongside Glimisave M3 850 Tablet Pr 15.

Drug-Disease Interactions

Glimisave M3 850 Tablet Pr 15 interacts with the following diseases:

Renal Impairment: Patients with kidney problems may experience metformin accumulation, increasing the risk of lactic acidosis.
Hepatic Insufficiency: This medicine should be used cautiously in liver disease as it may affect metabolism and clearance of the medicine.
Metabolic Acidosis: Glimisave M3 850 Tablet Pr 15 is contraindicated in patients with metabolic acidosis as it can worsen the condition.

Daily Dose

The daily dose of Glimisave M3 850 Tablet Pr 15 should be taken exactly as prescribed by your doctor. Your dosage may be adjusted based on your blood glucose levels and how well you respond to treatment. Never change your dose without consulting your doctor first.

Over Dose

Overdosing on Glimisave M3 850 Tablet Pr 15 may cause low blood sugar (hypoglycaemia). You might experience sweating, trembling, dizziness, headache, and hunger. Contact your doctor if you experience unusual symptoms.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take a double dose to make up for a missed one.

Store in a tightly closed container at room temperature (below 30°C).
Keep the medicine protected from light and moisture.
Store in a dry place away from direct sunlight.
Keep out of reach of children.
Do not use this medicine after the expiry date printed on the package.

Monitor your carbohydrate intake and choose complex carbohydrates (like whole grains) over simple sugars to help maintain steady blood glucose levels throughout the day.
Engage in regular physical activity (at least 30 minutes, 5 days a week) as exercise improves insulin sensitivity and helps lower blood sugar levels.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes, hyperglycaemia
Drug Category	Insulin secretagogue + Glucose reducer
Therapeutic Category	Antidiabetic medication

What if I miss a dose of Glimisave M3 850 Tablet Pr 15?

Take it as soon as you remember. If it is nearly time for your next dose, skip the missed one. Never take two doses together to make up for a missed dose.

How should I store Glimisave M3 850 Tablet Pr 15?

Store at room temperature (below 30°C) in a tightly closed container away from light, moisture, and reach of children.

How long does it take for Glimisave M3 850 Tablet Pr 15 to start working?

You may notice initial effects within a week, but full benefits typically appear after about two weeks of regular use with proper blood glucose monitoring.

What should I do if I experience symptoms of hypoglycaemia (low blood sugar)?

Immediately consume sugar sources like glucose tablets, fruit juice, or sweets. Contact your doctor afterwards as your medicine dose might need adjustment.

Can I drink alcohol while taking Glimisave M3 850 Tablet Pr 15 ?

It is best to avoid alcohol completely as it increases your risk of hypoglycaemia (low blood sugar) and lactic acidosis (a rare but serious condition).

What are the common side effects of Glimisave M3 850 Tablet Pr 15?

Common side effects include nausea, stomach discomfort, diarrhoea, metallic taste in mouth, and low blood sugar. Most side effects improve with time.

Should I take Glimisave M3 850 Tablet Pr 15 before or after meals?

Take this medicine with meals, preferably with breakfast. This helps reduce stomach-related side effects and improves how the medicine works in your body.

Last Updated On 14 May. 2025 | 2:44PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Shivarth Ambit, Plot No. 142/2, Ramdas Road, Off SBR, Near Swati Bungalows, Ahmedabad, Gujarat - 380054

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (n.d.). Metformin. In MedlinePlus. Retrieved 1 April 2025, from https://medlineplus.gov/druginfo/meds/a696005.html
MedlinePlus. (n.d.). Glimepiride. In MedlinePlus. Retrieved 1 April 2025, from https://medlineplus.gov/druginfo/meds/a696016.html
Corcoran, C., & Jacobs, T. F. (2023, August 17). Metformin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK518983/
Foretz, M., Guigas, B., & Viollet, B. (2023). Metformin: update on mechanisms of action and repurposing potential. Nature Reviews Endocrinology, 19(8), 460–476. https://doi.org/10.1038/s41574-023-00833-4
DrugBank. (n.d.). Glimepiride. Retrieved 1 April 2025, from https://go.drugbank.com/drugs/DB00222
Trerattanavong, K., & Tadi, P. (2023, July 4). Glimepiride. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK554600/

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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