Gantra 2.5mg Tablet 14 is used to manage chronic heart failure with reduced pumping capacity (reduced ejection fraction) in adults who have recently been hospitalised or needed intravenous treatment for worsening heart failure. It contains vericiguat, a soluble guanylate cyclase stimulator, and helps reduce the risk of death and further hospitalisation related to heart failure.
It works by helping blood vessels relax and widen, which improves blood flow and eases the workload on the heart. Take it with food, at the same time each day, exactly as prescribed. It is usually taken alongside other heart failure medicines. Continue taking it regularly even if you feel well, as heart failure needs long-term treatment.
Lifestyle measures that support heart failure treatment include limiting salt intake, monitoring your fluid intake as advised, staying as active as your doctor recommends, and limiting alcohol.
Before starting, tell your doctor if you have kidney or liver problems, low blood pressure, dehydration, or an irregular heartbeat, or if you are taking other medicines. This medicine is not recommended during pregnancy, as it may harm an unborn baby, and effective contraception is advised during treatment. Tell your doctor if you feel dizzy or light-headed, especially when standing up.
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Gantra 2.5Mg Tablet 14
Strip of 14 Units
MRP ₹1785.9
₹1428.72
₹127.56/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Gantra 2.5Mg Tablet 14
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Uses of Gantra 2.5Mg Tablet 14
Gantra 2.5mg Tablet 14 is used in adults with long-term heart failure and reduced ejection fraction who have recently had a worsening episode requiring hospitalisation or intravenous treatment.
Uses of Gantra 2.5mg Tablet 14 are:
• Chronic Heart Failure: Helps manage symptomatic long-term heart failure with reduced pumping capacity.
• Reducing Hospitalisation Risk: Lowers the risk of hospitalisation related to worsening heart failure.
• Reducing Cardiovascular Death Risk: Reduces the risk of death from cardiovascular causes in people with chronic heart failure.
Directions for Use of Gantra 2.5Mg Tablet 14
Follow these instructions while taking Gantra 2.5mg Tablet 14:
- Take this medicine exactly as prescribed by your doctor.
- Swallow the tablet whole with water.
- Take the medicine with food.
- Take the medicine at approximately the same time each day.
- Do not stop taking the medicine without consulting your doctor.
Route of Administration
Gantra 2.5mg Tablet 14 is taken orally.
Side Effects of Gantra 2.5Mg Tablet 14
Gantra 2.5mg Tablet 14 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Gantra 2.5mg Tablet 14:
• Cardiovascular: Low blood pressure (hypotension).
• Neurological: Dizziness and light-headedness, particularly when standing up suddenly.
• Blood: Anaemia (low red blood cell count), which may cause tiredness or paleness.
• Digestive: Feeling sick (nausea) and vomiting.
• Other: Headache.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing Gantra 2.5mg Tablet 14. However, if you experience any serious side effects or worsening of symptoms, consult your doctor.
Here are a few tips that may help:
- Dizziness: Avoiding sudden standing from a sitting or lying position may help reduce dizziness associated with blood pressure changes.
- Nausea: Taking the medicine with food may help reduce nausea.
How Gantra 2.5Mg Tablet 14 Works?
Gantra 2.5mg Tablet 14 contains the following active ingredient:
- Vericiguat (2.5 mg): It is a soluble guanylate cyclase (sGC) stimulator that helps improve the nitric oxide signalling pathway involved in cardiovascular function. It works by increasing cyclic guanosine monophosphate (cGMP) levels, which helps relax blood vessels, improve blood flow, support heart function, and reduce stress on the heart in patients with chronic heart failure.
Safety Measures & Warnings
Pregnancy
Gantra 2.5mg Tablet 14 should not be used during pregnancy unless specifically advised by your doctor. This medicine may cause harm to the developing baby. Inform your doctor immediately if you are pregnant or planning pregnancy during treatment.
Breastfeeding
Breastfeeding is not recommended during treatment with Gantra 2.5mg Tablet 14. Consult your doctor before taking this medicine while breastfeeding.
Alcohol
Alcohol may increase dizziness, light-headedness, or low blood pressure during treatment with Gantra 2.5mg Tablet 14. Limit or avoid alcohol intake during treatment.
Liver
Use this medicine with caution if you have liver disease. Severe liver impairment has not been adequately studied, and careful monitoring may be required in some patients.
Kidney
Use this medicine with caution if you have severe kidney disease. Patients on dialysis or with severe kidney impairment may require careful medical supervision during treatment.
Use In Driving And Operating Machinery
Gantra 2.5mg Tablet 14 may cause dizziness or low blood pressure in some individuals. Avoid driving or operating machinery if affected.
Allergy
Gantra 2.5mg Tablet 14 may cause dizziness or low blood pressure in some individuals. Avoid driving or operating machinery if affected.
Children
Gantra 2.5mg Tablet 14 is not recommended for use in children and adolescents under 18 years of age.
Older Patients
Older adults may be more sensitive to dizziness, hypotension, or weakness during treatment. Monitoring may be required in some patients.
Interactions of Gantra 2.5Mg Tablet 14
Drug-Drug Interactions
Gantra 2.5mg Tablet 14 may interact with the following medicines:
- Antihypertensive medicines (e.g., amlodipine, enalapril): Concurrent use may increase the risk of low blood pressure, dizziness, or fainting in some individuals. Blood pressure monitoring may be required during treatment.
- Other soluble guanylate cyclase stimulators (e.g., riociguat): Taking these medicines together may significantly increase the risk of severe hypotension and related cardiovascular complications. Concurrent use is contraindicated.
- PDE-5 inhibitors (e.g., sildenafil, tadalafil): Concurrent use may increase the risk of symptomatic hypotension, dizziness, or fainting. Combined use is generally not recommended.
- Organic nitrates (e.g., nitroglycerin, isosorbide mononitrate): Taking these medicines together may further reduce blood pressure in susceptible individuals. Careful monitoring may be advised during treatment.
- Diuretic medicines (e.g., furosemide, torsemide): Combined use may increase the risk of dehydration, dizziness, or low blood pressure, especially in patients with volume depletion. Monitoring may be required during treatment.
Drug-Disease Interactions
Gantra 2.5mg Tablet 14 should be used with caution if you have:
- Hypotension or low blood pressure: Vericiguat may further lower blood pressure and increase the risk of dizziness, fainting, or weakness in susceptible individuals.
- Heart failure with marked fluid depletion: Patients with dehydration or reduced circulating volume may have a higher risk of symptomatic hypotension during treatment.
Dosage of Gantra 2.5Mg Tablet 14
Daily Dose
Take Gantra 2.5mg Tablet 14 exactly as prescribed by your doctor. The dosage may be adjusted gradually depending on blood pressure, tolerability, clinical response, and heart failure status. Continue treatment regularly along with other prescribed heart failure therapies.
Over Dose
Overdose of Gantra 2.5mg Tablet 14 may increase the risk of severe hypotension, dizziness, fainting, weakness, or cardiovascular complications. Seek immediate medical attention if overdose is suspected.
Missed Dose
If you miss a dose of Gantra 2.5mg Tablet 14, take it as soon as you remember on the same day. If it is nearly time for the next scheduled dose, skip the missed dose and continue your regular schedule. Do not take two doses on the same day to compensate for the missed dose.
Storage
- Store Gantra 2.5mg Tablet 14 below 30°C.
- Keep the medicine protected from heat and moisture.
- Store in the original packaging.
- Protect from direct sunlight.
- Keep out of reach of children.
Special Dietary And Lifestyle Recommendation
- Follow a heart-healthy diet with controlled salt intake as advised by your doctor to help manage chronic heart failure.
- Monitor body weight regularly and report sudden weight gain, swelling, or worsening breathlessness to your doctor promptly.
- Limit excessive fluid intake if your doctor has advised fluid restriction for heart failure management.
- Engage in light physical activity or cardiac rehabilitation exercises if recommended by your doctor to help improve cardiovascular health.
- Avoid smoking and excessive alcohol intake, as these may worsen heart failure symptoms and cardiovascular health.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Chronic heart failure with reduced ejection fraction |
| Drug Category | Soluble guanylate cyclase (sGC) stimulator |
| Therapeutic Category | Heart failure medicine |
Frequently Asked Questions (FAQs)
What is Gantra 2.5mg Tablet 14 used for?
How does Gantra 2.5mg Tablet 14 help in heart failure?
Can Gantra 2.5mg Tablet 14 lower blood pressure?
Can Gantra 2.5mg Tablet 14 cause dizziness?
Should Gantra 2.5mg Tablet 14 be taken with food?
Can pregnant women take Gantra 2.5mg Tablet 14?
Can Gantra 2.5mg Tablet 14 be used together with other heart failure medicines?
What should I do if I feel faint or dizzy during treatment?
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Manufacturer details
Country of origin: GERMANY
References
- U.S. Food and Drug Administration. (2021). VERQUVO (vericiguat) tablets, for oral use [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/214377s000lbl.pdf
- European Medicines Agency. (2021). Verquvo (vericiguat): Product information. https://www.ema.europa.eu/en/documents/product-information/verquvo-epar-product-information_en.pdf
- Bayer Inc. (2023). VERQUVO® (vericiguat) product monograph. https://www.bayer.com/sites/default/files/2023-05/verquvo-pm-en.pdf
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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