Espin-AT Tablet is used to manage high blood pressure (hypertension) in adults. It is also used to manage angina pectoris, a type of chest pain caused by reduced blood flow to the heart.
It contains atenolol, a beta-blocker, and S-amlodipine, a calcium channel blocker, which work together to lower blood pressure and reduce the workload on the heart. Take it as prescribed, and continue taking it even when you feel well; do not stop suddenly without medical advice.
Limiting salt intake, staying physically active, maintaining a healthy weight and avoiding excessive alcohol support blood pressure and heart health alongside this medicine.
Tell your doctor if you have asthma, a slow heart rate, or kidney or liver problems before starting this medicine. Report any severe dizziness, swelling of the ankles or feet, or a very slow heartbeat to your doctor promptly.
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Espin At Tablet 10
Strip of 10 Units
MRP ₹89.53
₹71.62
₹8.95/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Espin At Tablet 10
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Uses of Espin At Tablet 10
Espin-AT Tablet is used in adults to lower high blood pressure and manage angina pectoris, helping to reduce the risk of serious cardiovascular events such as stroke and heart attack.
Uses of Espin-AT Tablet are:
• High Blood Pressure: Helps lower and control high blood pressure.
• Angina Pectoris: Helps manage chest pain caused by reduced blood flow to the heart.
• Cardiovascular Risk Reduction: Helps lower the risk of stroke and heart attack.
Directions for Use of Espin At Tablet 10
Follow these instructions while taking Espin-AT Tablet:
Swallow the tablet whole with a glass of water.
You can take this medicine with or without food.
It's important not to stop taking this medicine without consulting your doctor first.
Avoid crushing or chewing the tablet.
Try to take your dose at the same time each day for maximum effectiveness.
Remember, these are general guidelines. Always follow your doctor's specific advice regarding how to use this medicine.
Route of Administration
Espin-AT Tablet is taken orally.
Side Effects of Espin At Tablet 10
Espin-AT Tablet may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few Common Side Effects of Espin-AT Tablet:
• General: Fatigue may occur.
• Cardiovascular: A slow heart rate (bradycardia) may occur, which can make you feel tired or dizzy.
• Other: Swelling of the ankles or feet (oedema) may occur.
• Neurological: Dizziness and headache. Rising slowly from sitting or lying down can help with dizziness.
• Digestive: Feeling sick (nausea), loose motions (diarrhoea) or constipation.
If side effects do not improve or become serious, speak to your doctor promptly.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Espin-AT Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here's how you can manage some common side effects:
Fatigue: If this medicine makes you feel tired, consider taking it at bedtime.
Gastrointestinal disturbances: To minimise these symptoms, try taking Espin-AT Tablet with your meals.
How Espin At Tablet 10 Works?
Espin-AT Tablet contains two active ingredients that work together to lower blood pressure:
S(-)Amlodipine (2.5 mg): As a dihydropyridine calcium channel blocker, S-amlodipine lowers blood pressure by relaxing arterial smooth muscle which causes your blood vessels to widen or dilate, leading to reduced peripheral vascular resistance. This mechanism improves blood flow and oxygen delivery to the heart and reduces the burden on your heart.
Atenolol (50 mg): This component acts as a selective beta-1-adrenergic receptor blocker. It reduces the workload on your heart and lowers blood pressure by slowing down your heart rate, reducing the strength of heart muscle contractions, suppressing renin release from your kidneys which in turn decreases angiotensin II formation and aldosterone secretion, and reduces the outflow of certain nervous signals from your brain.
Safety Measures & Warnings
Pregnancy
Espin-AT Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor before starting this medicine.
Breastfeeding
Espin-AT Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.
Alcohol
While taking Espin-AT Tablet, it's advised to limit alcohol consumption as it may increase the risk of adverse effects such as dizziness and fainting.
Liver
Caution is advised while taking Espin-AT Tablet if you have mild to moderate liver impairment. This medicine may affect liver function. It's not recommended if you have severe liver diseases.
Kidney
This medicine is cleared by the kidneys, so caution is advised if you have a history of kidney problems. Consult your doctor before taking Espin-AT Tablet, especially if your kidney function is impaired.
Use In Driving And Operating Machinery
Since Espin-AT Tablet may cause dizziness, caution is advised while driving or operating heavy machinery until you know how this medicine affects you.
Allergy
Avoid using Espin-AT Tablet if you are allergic to atenolol, S-amlodipine, or any other ingredients in this medicine. Symptoms of an allergic reaction may include rash, itching, difficulty breathing or swelling of the face, lips or throat.
Children
Espin-AT Tablet should not be given to children under 18 years of age without medical supervision. Always consult your doctor before giving this medicine to a child.
Older Patients
Older patients should take Espin-AT Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Interactions of Espin At Tablet 10
Drug-Drug Interactions
Espin-AT Tablet interacts with the following medicines:
Antihypertensive Agents: Medicines such as lisinopril or losartan may interact with Espin-AT Tablet, potentially increasing the risk of low blood pressure, also known as hypotension.
Diuretics: When taken together with Espin-AT Tablet, diuretics like chlorthalidone may increase your blood sugar levels.
Antipsychotics: Medicines like chlorpromazine may interact with Espin-AT Tablet, potentially increasing atenolol levels in your body.
Non-steroidal anti-inflammatory drugs (NSAIDs): NSAIDs like ibuprofen may reduce the blood pressure-lowering effect of Espin-AT Tablet.
CYP3A4 Inhibitors: Medicines such as itraconazole and ritonavir can increase the level of S-amlodipine in your body.
CYP3A4 Inducers: Certain medications like rifampicin can decrease the level of S-amlodipine in your body.
Drug-Food Interactions
Espin-AT Tablet interacts with certain foods. You should avoid consuming grapefruit or its juice while taking this medication as it can increase the level of Samlodipine in your body, leading to increased side effects.
Drug-Disease Interactions
Espin-AT Tablet interacts with the following diseases:
Liver Disease: Patients with severe liver impairment should use caution when taking Espin-AT Tablet as atenolol may accumulate due to decreased liver clearance.
Kidney Disease: If you have impaired kidney function, dose adjustment may be required as atenolol is primarily eliminated by the kidneys.
Diabetes: Espin-AT Tablet could impact blood sugar control requiring you to monitor glucose levels closely.
Hyperthyroidism: Atenolol may mask the signs of developing hyperthyroidism, such as a fast heart rate. Abrupt withdrawal may intensify symptoms of hyperthyroidism or trigger a thyroid storm a severe and potentially lifethreatening form of thyrotoxicosis (excessive thyroid hormone in the body).
Heart Diseases: Patients with conditions like cardiogenic shock, second or thirddegree heart block, severe bradycardia (resting heart rate < 45 to 50 bpm), and decompensated heart failure should avoid using Espin-AT Tablet.
Dosage of Espin At Tablet 10
Daily Dose
The daily dose of Espin-AT Tablet should be taken as directed by your doctor. Your dosage may vary based on factors such as your condition's severity and your response to the medicine. Always follow your doctor's prescribed dosage and avoid exceeding it without his or her consultation.
Over Dose
Overdosing on Espin-AT Tablet may result in symptoms such as fatigue, dizziness, and slow heart rate. If you suspect you've taken more than the prescribed dosage, consult your doctor for advice.
Missed Dose
If you forget a dose of Espin-AT Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Don't increase your dose without speaking to your doctor.
Storage
Store Espin-AT Tablet below 30°C to maintain its effectiveness.
Keep it in a dry place, away from moisture.
Avoid exposing the medicine to direct sunlight or extreme heat.
Always keep this medicine out of reach and sight of children.
Check the pack for the expiry date and use the medicine before that.
Special Dietary And Lifestyle Recommendation
Reducing your intake of salt can help control high blood pressure, one condition that Espin-AT Tablet is used to manage. Consider using herbs or spices for flavour instead of salt.
Regular moderate exercise, such as brisk walking or cycling, can help lower your blood pressure and keep your heart healthy. Be sure to consult your doctor before starting any new exercise regimen.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Hypertension, Angina Pectoris |
| Drug Category | Beta 1 Blocker, Calcium Channel Blocker |
| Therapeutic Category | Antihypertensive |
Frequently Asked Questions (FAQs)
What is Espin-AT Tablet used for?
Espin-AT Tablet is used to manage hypertension (high blood pressure) and angina pectoris (chest pain).
How does Espin-AT Tablet work?
This medicine combines atenolol and S-amlodipine, reducing blood pressure by slowing the heart rate and relaxing arterial smooth muscle.
Can I take Espin-AT Tablet without food?
Yes, you can take this medicine with or without food. Consistency in timing is recommended.
What should I do if I experience side effects like dizziness or swollen ankles?
To manage these side effects, try rising slowly from a sitting position and elevate your legs periodically. Consult your doctor if symptoms persist.
Can I suddenly stop taking Espin-AT Tablet?
No, sudden discontinuation may worsen angina. Always consult your doctor before stopping this medication.
Is Espin-AT Tablet safe during pregnancy or lactation?
No, this medicine is not recommended for use during pregnancy or lactation. Always consult your doctor before starting any new medication.
Can Espin-AT Tablet interact with other medicines?
Yes, it can interact with other antihypertensive agents, diuretics, NSAIDs and some other medicines. Discuss all medications you're taking with your doctor.
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Manufacturer details
Country of origin: INDIA
References
U.S. Food and Drug Administration. (2012). Atenolol Tablets USP. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/018240s032lbl.pdf
U.S. Food and Drug Administration. (2019). New Drug Application 212895Orig1s000. https://www.accessdata.fda.gov/drugsatfda_docs/nda/2019/212895Orig1s000OtherR.pdf
Şen, S., Demir, M., Yiğit, Z., & Üresin, A. Y. (2018). Efficacy and Safety of S-Amlodipine 2.5 and 5 mg/d in Hypertensive Patients Who Were Treatment-Naive or Previously Received Antihypertensive Monotherapy. Journal of Cardiovascular Pharmacology and Therapeutics, 23(4), 318–328. https://doi.org/10.1177/1074248418769054
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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