Duphill M Tablet 10 is used as a maintenance treatment for asthma and other obstructive airway conditions when prescribed. It is a combination medicine containing doxofylline, a xanthine bronchodilator, and montelukast, a leukotriene receptor antagonist.
Doxofylline relaxes the airway muscles to improve airflow, while montelukast blocks leukotriene-mediated airway inflammation and narrowing. This medicine is not intended for the immediate relief of a sudden asthma attack.
Avoiding known triggers such as smoke, dust, pollen and pet dander, and keeping up with prescribed inhalers help control asthma and allergies.
This medicine can occasionally affect mood and behaviour. Stop taking it and contact your doctor straight away if you or your family notice agitation, aggression, anxiety, depression, sleep problems, nightmares, unusual thoughts or thoughts of self-harm. Before starting, tell your doctor if you have liver disease or a history of mental health problems, and about other medicines you take. Tell your doctor if you are pregnant or breastfeeding. Seek urgent medical help if your breathing gets worse or your reliever does not help. Do not stop taking this medicine for any other reason unless your doctor advises you to do so.
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Duphill M Tablet 10
Strip of 10 Units
Old MRP ₹160
MRP ₹150
₹75
₹7.5/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Duphill M Tablet 10
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Uses of Duphill M Tablet 10
Duphill M Tablet 10 is used as maintenance treatment for obstructive airway conditions such as asthma when prescribed.
Uses of Duphill M Tablet 10 are:
• Asthma Maintenance: Helps reduce airway narrowing and support long-term control of wheezing and breathlessness.
• Obstructive Airway Symptoms: Helps improve airflow in conditions associated with bronchospasm.
It is not a rescue medicine for a sudden asthma attack.
Directions for Use of Duphill M Tablet 10
- Swallow the tablet whole without chewing, crushing, or breaking it.
- The medicine can be taken either with or without food.
- It is recommended to take the tablet at the same time each day.
- Do not stop taking this medicine abruptly; always consult your doctor first.
Route of Administration
Duphill M Tablet 10 is taken orally.
Side Effects of Duphill M Tablet 10
Duphill M Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Duphill M Tablet 10:
• Nervous System: Headache.
• Digestive: Stomach pain, nausea and diarrhoea.
• Skin: Rash.
• Other: Cold-like symptoms.
If any side effect does not improve or becomes serious, speak to your doctor. Do not stop taking the medicine unless your doctor advises you to do so."
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Duphill M Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are a couple of tips to help manage two common side effects:
- Nausea: You could try taking your Duphill M Tablet 10 with food to lessen this effect.
- Insomnia: If you find it hard to sleep, consider taking your medicine early in the evening.
How Duphill M Tablet 10 Works?
Duphill M Tablet 10 composition contains Doxofylline (400 Mg) + Montelukast (10 Mg) as its active ingredients.
- Doxofylline (400 mg): It acts as a bronchodilator. It works by relaxing the smooth muscles of your airways. It does this by inhibiting certain enzymes in your body, leading to an increase in certain substances that promote muscle relaxation and reduce inflammation in the respiratory tract.
- Montelukast (10 mg): Montelukast is a leukotriene receptor antagonist. In simple terms, it blocks the action of substances called leukotrienes that cause inflammation during an asthma attack. By preventing these substances from causing inflammation and constriction of the airways, montelukast helps maintain open airways and reduces the frequency and intensity of asthma symptoms.
Safety Measures & Warnings
Pregnancy
If you are pregnant or planning to conceive, it’s important to consult your doctor before starting Duphill M Tablet 10. Although it may be safe in some cases, caution is generally advised, as the medication’s effects on the developing fetus are not fully understood.
Breastfeeding
Breastfeeding mothers should discuss the use of Duphill M Tablet 10 with their doctor, as it may pass into breast milk and affect the infant. Your doctor will assess the benefits versus potential risks and advise accordingly.
Alcohol
To avoid adverse effects, it is recommended to limit alcohol intake while taking Duphill M Tablet 10, as alcohol may increase the likelihood of side effects such as dizziness and drowsiness.
Liver
Patients with liver disorders should exercise caution when using Duphill M Tablet 10. Liver function may impact how the medication is processed in the body. Your doctor may perform liver function tests to ensure safe use and determine if dosage adjustments are necessary.
Kidney
If you have a history of kidney issues, inform your doctor before starting Duphill M Tablet 10. Kidney function may affect how the medication is eliminated from your body, so it is crucial to use it under medical supervision.
Use In Driving And Operating Machinery
Duphill M Tablet 10 may cause drowsiness or dizziness, which can impair your ability to drive or operate machinery safely. Avoid such activities if you experience these side effects, or wait until you know how the medication affects you.
Allergy
Duphill M Tablet 10 is contraindicated for people allergic to doxofylline or montelukast. Speak with your doctor if you have any known allergies before starting this medication.
Children
Duphill M Tablet 10 is generally not recommended for children under 18 unless prescribed by a paediatrician. The dosage and potential effects on children differ from adults, so always consult a doctor before administering this medication to children.
Older Patients
Elderly patients may be more sensitive to the effects of Duphill M Tablet 10, particularly regarding liver and kidney function. Older adults should use this medication only under strict medical supervision, with regular check-ups to monitor for potential side effects.
Interactions of Duphill M Tablet 10
Drug-Drug Interactions
Duphill M Tablet 10 interacts with the following medicines:
- Bronchodilators: Taking bronchodilators like theophylline alongside Duphill M Tablet 10 can increase the risk of toxicity. Your doctor may need to adjust the dose to prevent adverse effects.
- CYP3A4 Inhibitors: Medications such as ketoconazole and erythromycin, which inhibit the CYP3A4 enzyme, may raise doxofylline levels in your body, potentially increasing side effects. Always inform your doctor if you are on these medications.
- CYP3A4 Inducers: Medications like phenytoin and rifampicin, which induce CYP3A4, may reduce doxofylline’s effectiveness by lowering its levels in the body. Your doctor may need to adjust your dose to maintain the desired therapeutic effect.
Drug-Food Interactions
Certain foods can interact with Duphill M Tablet 10:
- Caffeine and chocolate: These may enhance the side effects of doxofylline, making you more susceptible to symptoms like rapid heartbeat or insomnia.
Drug-Disease Interactions
Duphill M Tablet 10 interacts with the following diseases:
- Liver disease: If you have a pre-existing liver condition, the medicine should be used cautiously as it could potentially worsen your condition.
- Kidney disorders: Similar to liver diseases, kidney conditions may require careful monitoring and dose adjustments when taking Duphill M Tablet 10.
Dosage of Duphill M Tablet 10
Daily Dose
Take the daily recommended dose of Duphill M Tablet 10 based on your individual condition and response to treatment. It's crucial to stick to this prescribed dosage and not alter it without consulting your doctor.
Over Dose
An overdose may lead to symptoms such as nausea, vomiting, diarrhoea, and an increased heart rate. If you unintentionally take more than the prescribed dose and experience any of these symptoms, inform your doctor.
Missed Dose
If you forget to take Duphill M Tablet 10, take it as soon as you remember. But if it is nearly time for the next dose, skip the missed one and continue with your regular schedule. Increasing your dosage without a doctor's consultation is not recommended.
Storage
- Keep Duphill M Tablet 10 at room temperature.
- Store the medicine in a dry place, away from light and moisture.
- Ensure it is safely out of reach of children.
- Always check the expiry date before use.
Special Dietary And Lifestyle Recommendation
- Avoid exposure to common asthma triggers such as house dust, pet dander, pollen, and cigarette smoke. This can help manage asthma symptoms effectively.
- Regular low-intensity exercise is beneficial. However, please consult your doctor before starting any exercise regimen, as intense physical activity may trigger asthma symptoms.
Fact Box
| Dosage Forms Available | Tablet
|
| Habit Forming | No |
| Ailment | Asthma, allergy-related respiratory issues |
| Drug Category | Bronchodilator, leukotriene receptor antagonist
|
| Therapeutic Category | Antiasthmatic
|
Frequently Asked Questions (FAQs)
What is the purpose of Duphill M Tablet 10?
How does Duphill M Tablet 10 work?
Can I stop taking Duphill M Tablet 10 when my symptoms improve?
Can Duphill M Tablet 10 be used for sudden breathing problems?
Are there any side effects of Duphill M Tablet 10?
Can I take other medications while using Duphill M Tablet 10?
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Manufacturer details
Country of origin: INDIA
References
- PubChem. (n.d.). Doxofylline. Nih.Gov. (Retrieved Nov 2024). https://pubchem.ncbi.nlm.nih.gov/compound/50942
- Doxofylline 2 g. (n.d.). Abcfarmaceutici.It. (Retrieved Nov 2024)https://www.abcfarmaceutici.it/uploads/news/40_file3_en.pdf
- Wermuth, H. R., Badri, T., & Takov, V. (Retrieved Nov 2024). Montelukast. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK459301/
- Effect of add-on Doxofylline on Lung Function in Stable COPD - Full Text View - ClinicalTrials.gov. (n.d.). https://classic.clinicaltrials.gov/ct2/show/NCT04238221
- Montelukast: MedlinePlus Drug Information. (n.d.-b). https://medlineplus.gov/druginfo/meds/a600014.html
- PubChem. (n.d.-j). Doxofylline. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Doxofylline
- Doxofylline: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB09273
- Montelukast: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.-b). DrugBank. https://go.drugbank.com/drugs/DB00471
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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