Canmab 440mg Injection 1

Canmab 440mg Injection 1 is used for the following:

• Treatment of HER2-positive metastatic breast cancer

• Management of breast cancer after chemotherapy

• First-line treatment with paclitaxel for breast cancer

• Therapy for HER2-positive stomach cancer

• Treatment of gastric adenocarcinoma

• Management of gastroesophageal junction adenocarcinoma

• Targeted therapy for tumours overexpressing the HER2 protein

• Slowing down the growth of certain aggressive cancer types

Follow these instructions when receiving Canmab 440mg Injection 1:

• This medicine must only be administered by a qualified healthcare professional in a clinical setting.

• The injection is administered through an intravenous infusion.

• The powder must be reconstituted with appropriate diluents before administration.

• Consult your doctor about any concerns before receiving this medicine.

Canmab 440mg Injection 1 is administered intravenously.

Canmab 440mg Injection 1 contains trastuzumab (440 mg), which works in the body through several mechanisms:

• Binds to HER2 protein: Trastuzumab attaches specifically to the HER2 protein found on cancer cell surfaces, blocking the growth signals that would normally cause cancer cells to multiply.

• Disrupts signalling pathways: This medicine interrupts the communication pathways inside cancer cells that rely on HER2, preventing the uncontrolled cell division that is characteristic of HER2-positive cancers.

• Recruits the immune system: Trastuzumab activates the immune system by promoting antibody-dependent cellular cytotoxicity (ADCC), allowing immune cells to recognise and destroy HER2-positive cancer cells.

• Inhibits tumour growth: By interfering with HER2-mediated pathways, the medicine slows down tumour growth and can potentially cause tumours to shrink over time.

• Keep Canmab 440mg Injection 1 refrigerated at 2-8°C (36-46°F).

• Never freeze the medicine as this will damage its effectiveness.

• Store in the original packaging to protect from light.

• Keep out of reach of children.

• Check the expiry date and do not use it after this date.

• Once reconstituted, use within the specified timeframe.

• Maintain good hygiene practices to reduce infection risk while receiving Canmab 440mg Injection 1, as this medicine may lower your white blood cell count.

• Consider avoiding crowded places during treatment periods to minimise exposure to infections, especially when your blood counts might be low.