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CompositionUrsokem-300 Tablet contains ursodeoxycholic acid, used to dissolve cholesterol gallstones and improve liver function. It is also effective in managing primary biliary cirrhosis by reducing inflammation and slowing disease progression.
Consult your doctor for a dosage suitable for your condition. Inform your healthcare provider of any pre-existing health issues or concurrent medications and report side effects promptly to ensure safe and effective treatment.
Ursokem-300 Tablet is used to treat cholesterol gallstones, primary biliary cirrhosis (PBC), and liver dysfunction in cystic fibrosis. It helps to dissolve stones, improve bile flow, and protect the liver from damage.
To use Ursokem-300 Tablet correctly, follow these steps:
Swallow the tablet whole with a glass of water.
It's best to take it after your meals.
Refrain from crushing or chewing the tablet.
Avoid taking more than what your doctor has advised.
Consult your doctor before altering the dose or stopping this medicine.
Ursokem-300 Tablet is taken orally.
Ursokem-300 Tablet may have the following common side effects:
Diarrhoea
Nausea
Abdominal pain
Vomiting
Rarely, skin reactions like rash, pruritus: This refers to an intense itching sensation.
Hair loss
In patients with primary biliary cirrhosis, a temporary worsening of liver function tests may be seen initially. This usually resolves with continued therapy.
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Ursokem-300 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Ursokem-300 Tablet with food.
Nausea: Consider taking this medicine after meals to lessen this effect.
Ursokem-300 Tablet contains ursodeoxycholic acid (300 mg) which carries out its functions in the body as follows:
Reduces Cholesterol Absorption: Ursodeoxycholic acid decreases the absorption of cholesterol from your intestines and lowers cholesterol secretion into bile. This leads to a reduction of saturation in bile and gradual dissolution of cholesterol gallstones.
Protects Liver Cells: By replacing toxic bile acids with non-toxic ursodeoxycholic acid, it protects liver cells from damage and boosts bile flow. This helps lessen inflammation and fibrosis in the liver.
Exhibits Immunomodulatory Properties: Ursodeoxycholic acid shows immunomodulatory capabilities that contribute to its positive effects in managing primary biliary cirrhosis and other liver diseases.
Caution is advised if you are pregnant and considering taking Ursokem-300 Tablet. It is best to consult your doctor before starting this medicine, as the safety during pregnancy has not been fully established.
Small amounts of ursodeoxycholic acid may pass into breast milk. If you are breastfeeding, make sure to discuss this with your doctor before starting Ursokem-300 Tablet.
There are no known interactions between Ursokem-300 Tablet and alcohol. However, excessive drinking can harm your liver and this medicine is used to manage liver conditions.
If you have advanced liver disease or decompensated cirrhosis, you may be more sensitive to the effects of Ursokem-300 Tablet. Discuss this with your doctor before starting the medicine.
No specific information suggests that Ursokem-300 Tablet affects kidney function. But if you have a history of kidney problems, consult your doctor before use.
Ursokem-300 Tablet does not usually affect your ability to drive or use machines. However, if you experience any side effects that might affect these abilities, avoid doing these tasks until you feel well enough.
Do not take Ursokem-300 Tablet if you have a known allergy to ursodeoxycholic acid or any other ingredients in the medicine. If you experience symptoms like rash or difficulty breathing after taking it, seek immediate medical help.
Ursokem-300 Tablet is meant for adult use. Always consult your doctor before giving any medicine to a child.
Elderly individuals should take Ursokem-300 Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Ursokem-300 Tablet interacts with the following medicines:
Bile Acid Sequestrants: Medicines like cholestyramine and colestipol can reduce the absorption of ursodeoxycholic acid, which could decrease the effectiveness of Ursokem-300 Tablet. These should be taken at least 2 hours apart.
Antacids: Certain antacids containing aluminium may lower the absorption of ursodeoxycholic acid, leading to reduced effectiveness of this medicine. Make sure to take them at least 2 hours apart.
Certain Antibiotics and Calcium Channel Blockers: Medicines such as ciprofloxacin (an antibiotic) and nitrendipine (a calcium channel blocker) can have their absorption affected by Ursokem-300 Tablet. Hence, these should be administered at least 2 hours before or after taking Ursokem-300 Tablet.
Ursokem-300 Tablet does not have any known interactions with specific foods. However, it is generally recommended to take this medicine after meals for optimal absorption.
Ursokem-300 Tablet interacts with the following diseases:
Advanced Liver Disease or Cirrhosis: Patients suffering from advanced liver disease or cirrhosis may be more sensitive to the effects of Ursokem-300 Tablet and could require dose adjustments under a doctor's guidance.
Complete Biliary Obstruction: In cases where bile cannot enter the intestine due to complete biliary obstruction, this medicine is contraindicated as it won't be able to work effectively.
You should take the daily dose of Ursokem-300 Tablet as prescribed by your doctor. The dosage may vary according to the severity of your condition and how you respond to the medication. Always adhere to the prescribed dosage and do not exceed it without consulting your doctor.
If you accidentally take more than the prescribed dosage of Ursokem-300 Tablet, you might experience some common side effects with increased intensity, such as nausea or abdominal discomfort. In this situation, it's important to inform your doctor.
In case you forget to take your regular dose of Ursokem-300 Tablet, don't worry. Take it as soon as you remember. But if it's nearly time for your next dose, just skip the missed one and continue with your regular schedule. Don't increase your dosage without discussing with your doctor.
Keep Ursokem-300 Tablet at room temperature, not exceeding 30°C.
Store the medicine in its original packaging, shielded from light and moisture.
Always place it out of reach of children to prevent accidental ingestion.
Lastly, keep an eye on the expiry date and do not use the medicine beyond this point.
If you suffer from gallstones, consider adopting a diet low in cholesterol. This can help manage your condition by reducing the formation of new gallstones.
For those with primary biliary cirrhosis or other liver diseases, a balanced diet rich in vitamins and minerals can support liver function. Avoid alcohol as it may exacerbate liver damage.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Cholesterol Gallstones, Primary Biliary Cirrhosis |
| Drug Category | Bile Acid |
| Therapeutic Category | Hepatoprotective |
Ursokem-300 Tablet helps dissolve small cholesterol gallstones and manages primary biliary cirrhosis, a chronic liver disease that damages bile ducts.
The medicine reduces cholesterol absorption, decreases its secretion into bile, and replaces toxic bile acids with non-toxic ones to protect liver cells.
The safety of this medicine during pregnancy hasn't been established. You should use it only if your doctor advises that the benefits outweigh the risks.
Small amounts of the active ingredient may pass into breast milk. Consult your doctor to understand the risks and benefits.
Use it cautiously if you have advanced liver disease or cirrhosis, and avoid it if you have complete biliary obstruction or known hypersensitivity to the ingredients.
Yes, certain medications like bile acid sequestrants and antacids containing aluminium can reduce its effectiveness. Inform your doctor about all medicines you're taking.
Store it at room temperature (15-30°C) in a tightly closed container, away from light and moisture, and out of children's reach.
Check out Editorial Policy
National Center for Biotechnology Information. (2021). The Role of Ursodeoxycholic Acid in Non-Alcoholic Fatty Liver Disease: A Systematic Review. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578816/ on 1 April 2024.
U.S. Food and Drug Administration. (2013). Highlights of prescribing information: Ursodiol. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/020675s022lbl.pdf on 1 April 2024.
National Institute of Diabetes and Digestive and Kidney Diseases. (2017, September 25). Ursodiol (Ursodeoxycholic acid). LiverTox - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK548309/
Ursodeoxycholic acid: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01586
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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