Topram 5 MG Tablet 10

Cassel Research Laboratories Pvt Ltd

Pack of 10 Units

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Store Below 30^o C

Composition

Ramipril (5 Mg)

Strength:

5 MG 2.5 MG

Topram 5 MG Tablet 10 is primarily used to manage high blood pressure, also known as hypertension. This medicine belongs to a group of medications called angiotensin-converting enzyme (ACE) inhibitors.

This medicine is also used to prevent cardiovascular events like heart attacks or strokes associated with hypertension. It has been found beneficial in reducing the risk of death in patients who are over 55 years of age with a history of particular health conditions such as coronary artery disease, peripheral vascular disease, or diabetes.

Before starting this medicine, you must consult your doctor and inform them about any pre-existing conditions or ongoing medications. If you observe any side effects while on this medication, notify your doctor immediately. For optimal benefits, continue taking the medicine for the duration prescribed by your doctor.

Topram 5 MG Tablet 10 is used for the following conditions:

High blood pressure or hypertension
Cardiovascular events like heart attacks or strokes

Swallow the whole tablet with a glass of water.
Avoid crushing or chewing the tablet.
Try to take the medicine at the same time each day for maximum effectiveness.
Take the medicine in the dosage and frequency prescribed by your doctor.
Do not alter your dosage or discontinue the medication halfway without consulting your doctor.

Topram 5 MG Tablet 10 is taken orally.

Topram 5 MG Tablet 10 may have the following common side effects:

Nausea or vomiting
Headache
Dizziness
Fatigue
Dry cough

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea or vomiting at home by taking the medicine with food or after your meals.

Topram 5 MG Tablet 10 contains ramipril (5 mg) as the active ingredient. It works in the human body in the following manner:

Ramipril inhibits the angiotensin-converting enzyme (ACE), which converts angiotensin I to angiotensin II in your body. Angiotensin II is a substance that stimulates the release of vasopressin, which causes vasoconstriction (narrowing of blood vessels) and increases blood pressure.
By blocking ACE, ramipril leads to the widening (vasodilation) of blood vessels, helping reduce blood pressure.
It also reduces the secretion of the aldosterone hormone from the adrenal gland, leading to decreased sodium and fluid retention.
The medicine also increases the kidneys' excretion of sodium and water, which helps reduce blood volume and pressure.

Pregnancy

Topram 5 MG Tablet 10 is contraindicated in pregnancy, especially during the second and third trimesters, as it can harm your unborn baby. If you are pregnant or planning to conceive, consult your doctor before taking this medicine.

Breastfeeding

This medicine is contraindicated while breastfeeding as ramipril may pass into breast milk and affect your nursing infant. Always consult your doctor to understand the potential risks and benefits if you are nursing.

Alcohol

Avoid consuming alcohol while on this medication as it may increase the risk of side effects such as dizziness, fatigue, or low blood pressure. Always consult your doctor regarding alcohol intake.

Liver

If you have liver health issues, be cautious while taking this medicine. This medicine may affect your liver function. Always discuss this with your doctor before starting this medication.

Kidney

For those with kidney health issues, caution is advised when using this tablet. Always consult your doctor before starting this medicine.

Using Machines & Driving

Topram 5 MG Tablet 10 could cause dizziness or fatigue in some individuals. If you experience these side effects, avoid driving or operating heavy machinery until you feel better.

Allergy

This medicine is contraindicated if you have ever had an allergic reaction to ramipril or any other ACE inhibitors. Always discuss your allergies with your doctor.

Children

This medicine is not indicated for use in children below 18 years. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take this medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status, especially if you are above 70 years old or have liver and kidney issues.

Drug-Drug Interactions

Topram 5 MG Tablet 10 may interact with the following medications:

Diuretics: When taken with Topram 5 MG Tablet 10, medicines like spironolactone and triamterene can increase your blood potassium levels, causing excessive hypotension (low blood pressure).
Non-steroidal anti-inflammatory drugs (NSAIDs): NSAIDs such as ibuprofen and naproxen, when used alongside this medicine, may increase your risk of kidney damage. They can also reduce the effectiveness of the tablet.
Mood stabilizers such as Lithium: This medicine may increase the level of lithium (used for mood disorders) in your blood, causing adverse effects.
Angiotensin receptor blockers (ARBs): Medicines like losartan or valsartan may interact with this tablet, potentially increasing the risk of high potassium levels in your blood, low blood pressure, and kidney dysfunction.

Drug-Food Interactions

Topram 5 MG Tablet 10 may interact with certain foods, such as:

High-potassium foods: Consuming foods rich in potassium while taking this medicine may lead to hyperkalaemia or high potassium levels in your blood.
High-sodium foods: Foods rich in sodium, like processed cheese and seafood, may reduce the effectiveness of the medicine.

Drug-Disease Interactions

Topram 5 MG Tablet 10 may interact with the following diseases:

Hyperkalaemia: This medicine is contraindicated in patients with hyperkalaemia (high blood levels of potassium) as it could worsen their condition.
Angioedema: Patients with hereditary or idiopathic angioedema (swelling or inflammation under your skin) are also contraindicated from taking this medicine.
Liver or kidney disease: This medicine should be used cautiously in patients with liver or kidney problems as it could exacerbate their condition.

Daily Dose

Your doctor will prescribe the daily dose of Topram 5 MG Tablet 10 based on individual factors such as the severity of your condition and how you respond to treatment. For further details regarding the dosage, please refer to the package insert.

Over Dose

Taking an overdose of the medicine could potentially lead to common side effects like nausea, fatigue, or headache. If you suspect an overdose, inform your doctor promptly.

Missed Dose

If you forget to take the medicine at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Store Topram 5 MG Tablet 10 at room temperature, ideally below 30°C.
Keep it away from excessive heat and moisture.
Always store the medicine in a tightly closed container.
Ensure the medicine is kept out of reach of children.
Use the tablet before its expiry date for optimum effectiveness.

Aim to maintain a low-salt diet. Excessive salt can increase your blood pressure, so consider limiting your intake.
Regular physical activity can also help manage high blood pressure. Try incorporating moderate exercise, such as walking or cycling, into your daily routine. However, always consult your doctor before starting any new exercise programme.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Hypertension, Heart Failure
Drug Category	ACE Inhibitors
Therapeutic Category	Antihypertensives

What is Topram 5 MG Tablet 10 used for?

Topram 5 MG Tablet 10 manages high blood pressure and prevents cardiovascular events such as heart attack or stroke.

How does Topram 5 MG Tablet 10 work?

This medicine contains ramipril as the active ingredient, which inhibits ACE, a body enzyme. This leads to widened blood vessels, reduced blood pressure, and less strain on the heart.

Can I take Topram 5 MG Tablet 10 with food?

Yes, you can take Topram 5 MG Tablet 10 with food or after your meals. However, for optimal effectiveness, remember to take it at the same time each day.

What if I miss a dose of Topram 5 MG Tablet 10?

If you miss a dose, take it as soon as possible unless it's nearly time for your next dose. Avoid doubling doses without consulting your doctor.

Are there any side effects of Topram 5 MG Tablet 10?

Yes, the common side effects of the medicine include headache, dizziness, fatigue, nausea, dry cough, and low blood pressure. If these symptoms persist or worsen, consult your doctor.

Are there any precautions I need to follow while taking Topram 5 MG Tablet 10?

Yes, it's not recommended during pregnancy or breastfeeding or for those with hyperkalaemia or a history of angioedema. Always discuss your health issues with your doctor before starting this medicine.

How should I store Topram 5 MG Tablet 10?

Store the medicine at room temperature (below 30°C) in a tightly closed container, away from moisture and heat. Keep the medicine out of children's reach.

Last Updated On 13 May. 2025 | 11:18AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Medical Content Writer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

P K 19, PHASE V, INDUSTRIAL ESTATE, EKKATTUTHANGAL, CHENNAI - 600 097

Expiry on or after: January 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. ALTACE (ramipril) Capsules, Oral. (2013, September). accessdata.fda.gov. https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019901s060lbl.pdf
Chauhan, M., Patel, J. B., & Ahmad, F. (2023, August 17). Ramipril. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK537119/
Ramipril: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00178
Ramipril. (n.d.). sciencedirect.com. https://www.sciencedirect.com/topics/chemistry/ramipril
Antihypertensive efficacy, tolerance, and safety of long-term treatment with ramipril in patients with mild-to-moderate essential hypertension. (1991). PubMed. https://pubmed.ncbi.nlm.nih.gov/1725024/
Doggrell, S. A. (2001). Is ramipril the pril for diabetes and kidney disease? Drugs of Today, 37(5), 321. https://doi.org/10.1358/dot.2001.37.5.627954

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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