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CompositionMTX 7.5 mg Tablet is used to manage rheumatoid arthritis by reducing joint inflammation, pain, and stiffness. It is also prescribed for severe psoriasis and is used in the treatment of certain cancers such as breast cancer, lymphoma, and leukaemia. This medicine must be taken strictly under medical supervision. Follow the prescribed dosage carefully, inform your doctor about other medicines, and report side effects immediately.
MTX 7.5 mg Tablet is used to reduce joint inflammation and pain in autoimmune disorders, slow excessive skin cell growth in psoriasis, and manage certain cancers. It helps control abnormal cell activity, limits disease progression, and improves symptom control under strict medical supervision.
Here is how you should take MTX 7.5 mg Tablet:
Take the tablet whole with a glass of water.
Do not crush or chew the tablet.
Follow the prescribed dosage from your doctor.
Do not stop taking this medicine without consulting your doctor first.
MTX 7.5 mg Tablet is taken orally.
MTX 7.5 MG Tablet may cause side effects such as nausea, vomiting, stomach discomfort, mouth ulcers or sores, fatigue, dizziness, temporary hair loss, loss of appetite, and mild headache. Regular monitoring is advised during treatment.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of MTX 7.5 mg Tablet . However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some tips to manage certain common side effects:
Nausea and vomiting: Try taking MTX 7.5 mg Tablet with food to minimise this effect.
Stomach discomfort: Consider taking this medicine after meals to lessen this discomfort.
MTX 7.5 mg Tablet contains methotrexate (7.5 mg), which works on your body as follows:
Inhibits Dihydrofolate Reductase: Methotrexate blocks an enzyme in your body called dihydrofolate reductase (DHFR). This enzyme is crucial for making DNA and RNA in cells.
Interferes with Cell Growth: By blocking DHFR, methotrexate disrupts the production of nucleic acids, proteins, and other components necessary for cell growth and survival.
Slows Skin Cell Growth: In cases of psoriasis, methotrexate slows down the excessive growth and buildup of skin cells.
Suppresses Immune System: Methotrexate's action is particularly effective against rapidly dividing cells like overactive immune cells in autoimmune disorders like rheumatoid arthritis.
MTX 7.5 mg Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, it is essential to discuss this with your doctor before starting this medicine.
Mtx 7.5 MG Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.
Consuming alcohol while taking MTX 7.5 mg Tablet may increase the risk of liver damage. It's best to consult your doctor for advice on alcohol consumption.
Caution is advised while taking MTX 7.5 mg Tablet if you have mild to moderate liver impairment. It is not recommended for severe liver diseases. This medicine may affect liver function.
If you have a history of kidney problems, it is advisable to consult your doctor before taking MTX 7.5 mg Tablet .
Take care when driving or operating machinery, as MTX 7.5 mg Tablet may cause dizziness or fatigue.
MTX 7.5 mg Tablet should not be used by those who have an allergy to methotrexate or any other ingredients in the tablet.
As this medicine is meant for adults, caution is advised when considering giving MTX 7.5 mg Tablet to children under 18 years of age.
Older patients should take MTX 7.5 mg Tablet under medical supervision as they may be more susceptible to its side effects and might also have liver and kidney issues. Your doctor will guide you based on your health status.
MTX 7.5 mg Tablet interacts with the following medicines:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): Medicines like ibuprofen and naproxen can increase the risk of side effects when taken with MTX 7.5 mg Tablet.
Antibiotics: Certain antibiotics such as penicillin and tetracycline can interact with this medicine, potentially altering its effects.
Proton Pump Inhibitors: Medicines like omeprazole and lansoprazole may increase the levels of methotrexate in the body, potentially leading to toxicity.
Certain foods may interact with MTX 7.5 mg Tablet.
High-Protein Foods: Consuming a high-protein diet may reduce the absorption of methotrexate, potentially decreasing its effectiveness.
MTX 7.5 mg Tablet interacts with the following diseases:
Kidney Disease: Patients with kidney disease should be monitored closely as MTX 7.5 mg Tablet could potentially worsen their condition.
Liver Disease: This medicine could exacerbate liver disease, making it essential for patients to be monitored closely.
Diabetes: Methotrexate could impact blood sugar control in diabetic patients, making glucose level monitoring necessary during treatment.
Lung Diseases: Methotrexate can cause lung problems; thus, people with a history of lung diseases should use this medicine cautiously.
The daily recommended dose of MTX 7.5 mg Tablet should be taken as directed by your doctor. Your dosage may vary based on your condition and how you're responding to the medicine. Always follow your doctor's instructions, and don't exceed the prescribed dosage without consultation.
Taking more than your prescribed dose of MTX 7.5 mg Tablet can cause side effects like nausea, vomiting, and fatigue. If you've taken too much, let your doctor know right away.
If you've missed a dose of MTX 7.5 mg Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and carry on with your regular schedule. Never increase your dosage without talking to your doctor first.
Store MTX 7.5 mg Tablet at room temperature.
Protect the medicine from light and moisture.
Keep it out of sight and reach of children.
Remember to use this medicine before its expiry date.
If you're managing rheumatoid arthritis with MTX 7.5 mg Tablet, try to include foods rich in omega-3 fatty acids like fish, walnuts, and flaxseeds in your diet; these can help reduce inflammation.
For individuals using this medicine for psoriasis, it's beneficial to maintain a healthy weight through balanced diet and regular exercise; excess weight can worsen psoriasis symptoms.
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Rheumatoid Arthritis, Psoriasis, Cancer |
| Drug Category | DHFR Inhibitor |
| Therapeutic Category | Antimetabolite |
It's primarily used to manage rheumatoid arthritis and psoriasis, and sometimes certain types of cancer.
The medicine inhibits a key enzyme involved in cell growth and division, which helps manage the symptoms of certain diseases.
MTX 7.5 mg Tablet is taken orally, as directed by your doctor.
Common side effects include nausea, mouth sores, fatigue, headache, and temporary hair loss.
Inform your doctor about any medical conditions you have and any other medicines you're taking before starting this medicine.
Store at room temperature, away from light and moisture; keep out of reach of children.
No, it isn't safe as it can cause birth defects and pass into breast milk; consult your doctor for alternatives.
Check out Editorial Policy
Methotrexate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. Retrieved 12 October 2024, from
DailyMed - METHOTREXATE SODIUM tablet. (n.d.).Retrieved 12 October 2024, from
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=89c05ea3-3be1-46dd-b112-29c436fd7289
Methotrexate sodium (Cancer treatment). (2008, May 21). Cancer.gov. Retrieved 12 October 2024, from
https://www.cancer.gov/about-cancer/treatment/drugs/methotrexate
Onda, K., Honma, T., & Masuyama, K. (2023). Methotrexate-related adverse events and impact of concomitant treatment with folic acid and tumor necrosis factor-alpha inhibitors: An assessment using the FDA adverse event reporting system. Frontiers in Pharmacology, 14. Retrieved 12 October 2024, from https://doi.org/10.3389/fphar.2023.1030832
Methotrexate: Medlineplus drug information. (n.d.). Retrieved 12 October 2024, from
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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