Macdaxa 150 Capsule 10 is used to prevent and treat dangerous blood clots, such as those occurring in deep vein thrombosis (DVT) and pulmonary embolism (PE). Containing the active ingredient dabigatran etexilate, this medicine is an anticoagulant (blood thinner) that works by specifically inhibiting thrombin, a key enzyme necessary for blood clotting. It is commonly prescribed for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation, for clot prevention following orthopaedic surgery, and to prevent the recurrence of DVT and PE in adults and children.
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Macdaxa 150 Capsule 10
Strip of 10 Units
Old MRP ₹145
MRP ₹135.94
₹108.75
₹13.59/Units
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CompositionAbout Macdaxa 150 Capsule 10
Uses of Macdaxa 150 Capsule 10
Macdaxa 150 Capsule 10 is an anticoagulant (blood thinner) used for the prevention of stroke and systemic embolism in adults with non-valvular atrial fibrillation, and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as preventing their recurrence.
Directions for Use of Macdaxa 150 Capsule 10
Here's how you should take Macdaxa 150 Capsule 10:
- Swallow the capsule whole with a glass of water. Avoid chewing or crushing it.
- Take this medicine as advised by your doctor. Do not alter the dose or stop taking it without medical guidance.
- Consult your doctor for specific advice related to your health condition.
Route of Administration
Macdaxa 150 Capsule 10 is taken orally.
Side Effects of Macdaxa 150 Capsule 10
Macdaxa 150 Capsule 10 may lead to stomach pain, diarrhoea, nausea, and an increased risk of bleeding or bruising.
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Macdaxa 150 Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are a couple of tips to manage common side effects:
- Stomach pain: You might find it helpful to take Macdaxa 150 Capsule 10 with a meal or snack.
- Diarrhoea: Try taking your dose at night if it leads to frequent loose bowel movements during the day.
How Macdaxa 150 Capsule 10 Works?
Macdaxa 150 Capsule 10 contains Dabigatran Etexilate (150 mg), which acts on your body as follows:
- Direct thrombin inhibition: Dabigatran etexilate blocks an enzyme called thrombin in your body. Thrombin plays a crucial role in blood clot formation.
- Prevention of clot formation: By blocking the activity of thrombin, dabigatran etexilate prevents the conversion of fibrinogen to fibrin, thereby reducing the formation of blood clots. This action makes your blood less likely to clot, decreasing the risk of serious cardiovascular events.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Macdaxa 150 Capsule 10 if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
Macdaxa 150 Capsule 10 is not recommended for breastfeeding women. Discuss with your doctor to understand the potential risks and benefits before starting this medicine.
Alcohol
Avoid consuming alcohol while taking Macdaxa 150 Capsule 10, as it may increase the risk of bleeding.
Liver
If you have liver problems, discuss them with your doctor before starting the Macdaxa 150 Capsule 10. This medicine may affect liver function, especially in severe cases.
Kidney
Caution is advised before using Macdaxa 150 Capsule 10 if you have a history of any kidney problems. Consult your doctor to understand the potential risks and benefits.
Using Machines & Driving
No specific information is available about whether the Macdaxa 150 Capsule 10 affects your ability to drive or operate machinery. However, as with all medications, ensure you know how it affects you before driving or using machines.
Allergy
If you have a known allergy to Dabigatran Etexilate or any other ingredients present in Macdaxa 150 Capsule 10, avoid using this medicine.
Children
Macdaxa 150 Capsule 10 should be given with caution to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
Older Patients
Older patients should take Macdaxa 150 Capsule 10 under medical supervision, as they may be more susceptible to its side effects. They might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.
Interactions of Macdaxa 150 Capsule 10
Drug-Drug Interactions
Macdaxa 150 Capsule 10 interacts with the following medicines:
- Anticoagulants: Other anticoagulant medicines like warfarin and heparin can increase the risk of bleeding when taken with this capsule.
- NSAIDs: Non-steroidal anti-inflammatory drugs such as ibuprofen and naproxen can also heighten the risk of bleeding when taken alongside this medicine.
- Anti-platelet drugs: Medicines like aspirin and clopidogrel may further enhance the chance of bleeding when combined with this capsule.
- P-glycoprotein inducers: Medications like rifampicin can reduce the effectiveness of Macdaxa 150 Capsule 10 due to increased metabolism.
- P-glycoprotein inhibitors: Certain medicines such as ketoconazole and dronedarone can increase exposure to dabigatran, thereby increasing its anticoagulant effects.
Drug-Food Interactions
There are no known significant food interactions with Macdaxa 150 Capsule 10.
Drug-Disease Interactions
Macdaxa 150 Capsule 10 interacts with the following diseases:
- Bleeding disorders: Active bleeding disorders may be exacerbated by this medication due to its anticoagulant properties.
- Stomach ulcers: The risk of serious bleeding is elevated in patients with stomach ulcers who take this medicine.
- Severe kidney or liver dysfunction: Patients with severe kidney or liver disease may experience a heightened risk of bleeding due to reduced excretion of dabigatran.
Dosage of Macdaxa 150 Capsule 10
Daily Dose
The daily dose of Macdaxa 150 Capsule 10 is taken as directed by your doctor. This dosage could vary based on factors like your current health condition and how your body responds to the medicine. Always follow the prescribed dosage and never change it without consulting your doctor.
Over Dose
If you happen to take more than the prescribed dose of Macdaxa 150 Capsule 10, you may experience side effects such as stomach pain, diarrhoea, or nausea. If these symptoms persist or worsen, please inform your doctor.
Missed Dose
If you forget to take your regular dose of Macdaxa 150 Capsule 10, take it as soon as you remember. However, if it's nearing time for your next dose, skip the missed one and continue with your usual dosage schedule. Never increase your dosage without consulting your doctor.
Storage
- Store Macdaxa 150 Capsule 10 at room temperature, specifically between 20 °C and 25 °C.
- Protect it from direct sunlight, heat, and moisture.
- Keep this medicine in its original packaging until it's time to take it.
- Always keep the capsule out of the reach of children.
- Check the expiration date before use and never take the medicine if it's past this date.
Diet & Lifestyle
- To help manage conditions treated by Macdaxa 150 Capsule 10, consider maintaining a balanced diet with plenty of fruits and vegetables. These foods are rich in vitamins that support good blood health and help reduce the risk of blood clots.
- Limit alcohol intake while you are taking this medicine. Alcohol can increase your risk of bleeding, a potential side effect of Macdaxa 150 Capsule 10.
Fact Box
| Available Dosage Types | Capsule |
| Habit Forming | No |
| Ailment | Stroke, Deep Vein Thrombosis, Pulmonary Embolism |
| Drug Category | Direct Thrombin Inhibitor |
| Therapeutic Category | Anticoagulant |
Frequently Asked Questions (FAQs)
What is Macdaxa 150 Capsule 10 used for?
Macdaxa 150 Capsule 10 is primarily used to manage blood clot formation, reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation.
How does Macdaxa 150 Capsule 10 work?
The active ingredient, dabigatran etexilate, in Macdaxa 150 Capsule 10 inhibits thrombin, a key enzyme involved in blood clotting, thus reducing the formation of blood clots.
Can I chew or crush the Macdaxa 150 Capsule 10?
No, the capsules should be swallowed whole with water. Chewing or crushing them can alter the medicine's effectiveness.
What are the common side effects of this medicine?
Common side effects include stomach pain, indigestion, frequent loose or liquid bowel movements (diarrhoea), nausea, and increased risk of bruising or bleeding.
Is it safe to take Macdaxa 150 Capsule 10 during pregnancy or while breastfeeding?
It's recommended to consult your doctor before taking this medicine during pregnancy or breastfeeding as it is not typically recommended for use during these periods.
Can I consume alcohol while taking this medicine?
Avoid alcohol while on this medication as it can increase the risk of bleeding. Always consult your doctor for personalized advice.
Are there any precautions I should take before starting this medication?
Yes, inform your doctor if you have an active bleeding disorder, organ diseases like stomach ulcers or severe kidney or liver dysfunction, recent fractures, head injuries or surgeries.
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Manufacturer details
Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: April 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- U.S. Food and Drug Administration. (2012). Pradaxa: Highlights of prescribing information. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022512s016lbl.pdf
- Dabigatran etexilate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06695
- Dabigatran Etexilate Accord | European Medicines Agency (EMA). (n.d.). European Medicines Agency (EMA). https://www.ema.europa.eu/en/medicines/human/EPAR/dabigatran-etexilate-accord
- Cheng, J. W. M., & Vu, H. (2012). Dabigatran Etexilate: An Oral Direct Thrombin Inhibitor for the Management of Thromboembolic Disorders. Clinical Therapeutics, 34(4), 766–787. https://doi.org/10.1016/j.clinthera.2012.02.022
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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