Linaliglip M 2.5/500 Tablet 15

Steris Healthcare

Strip of 15 Units

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Composition

Linagliptin (2.5 Mg) + Metformin (500 Mg)

Linaliglip M 2.5/500 Tablet 15 is used to manage type 2 diabetes mellitus in adults. It is a combination medicine that belongs to the class of antidiabetic medications.

This medicine helps reduce the risk of diabetes-related complications such as kidney damage (nephropathy), nerve damage (neuropathy), and eye damage (retinopathy). It may also aid in managing diabetic foot ulcers and delayed wound healing, which are common problems for people with uncontrolled diabetes.

You should take this medicine as directed by your doctor, who will determine the appropriate dosage and frequency based on your condition. Inform your doctor about any pre-existing conditions or ongoing medications before beginning this medicine. If you notice any side effects while taking this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

Linaliglip M 2.5/500 Tablet 15 is used for the following:

Managing type 2 diabetes mellitus in adults
Improving blood sugar control with diet and exercise
Reducing risk of diabetic kidney damage
Preventing diabetic nerve damage
Managing diabetic eye complications
Helping with diabetic foot ulcers
Addressing delayed wound healing in diabetes

Follow these instructions while taking Linaliglip M 2.5/500 Tablet 15:

Swallow the tablet whole with a glass of water.
Avoid crushing, chewing, or splitting the tablet.
Take the medicine regularly at the same time each day.

Linaliglip M 2.5/500 Tablet 15 is taken orally.

Linaliglip M 2.5/500 Tablet 15 may have the following common side effects:

Diarrhoea
Nausea
Vomiting
Abdominal discomfort
Headache
Nasopharyngitis: Inflammation of the nasal passages and the upper part of the throat, commonly known as a cold
Hypoglycaemia: Blood sugar drops below normal levels, causing symptoms like shakiness, sweating, hunger, and confusion
Vitamin B12 deficiency

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Linaliglip M 2.5/500 Tablet 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Taking Linaliglip M 2.5/500 Tablet 15 with meals can help reduce this side effect.
Hypoglycaemia: If you experience symptoms of low blood sugar, taking Linaliglip M 2.5/500 Tablet 15 at consistent times each day with food can help maintain steady blood sugar levels.

Linaliglip M 2.5/500 Tablet 15 contains two active ingredients:

Linagliptin (2.5 mg): This component is a dipeptidyl peptidase-4 (DPP-4) inhibitor, which blocks the DPP-4 enzyme in your body. By doing this, it increases the levels of incretin hormones that stimulate your pancreas to produce more insulin when needed.
Metformin (500 mg): This belongs to the biguanide class of medicines. It works by lowering glucose production in your liver, delaying glucose absorption from your intestines, and improving insulin sensitivity in your body, helping it utilise insulin more effectively.

Pregnancy

Linaliglip M 2.5/500 Tablet 15 is not recommended during pregnancy, especially in the second and third trimesters. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Caution is advised while taking Linaliglip M 2.5/500 Tablet 15 if you are breastfeeding. It is best to consult your doctor before taking this medicine to weigh the potential risks and benefits.

Alcohol

Avoid alcohol while taking Linaliglip M 2.5/500 Tablet 15 as it may increase the risk of a serious condition called lactic acidosis. This condition can cause symptoms like unusual muscle pain, feeling cold, dizziness, and stomach discomfort.

Liver

Caution is advised while taking Linaliglip M 2.5/500 Tablet 15 if you have liver problems. The medicine should be used carefully in patients with liver disease.

Kidney

Caution is advised before using Linaliglip M 2.5/500 Tablet 15 if you have kidney problems. This medicine is not recommended for patients with severe kidney impairment (when eGFR is less than 30 mL/min). Your doctor will check your kidney function before and during treatment.

Using Machines & Driving

If you experience low blood sugar (hypoglycaemia) while taking Linaliglip M 2.5/500 Tablet 15, which can cause dizziness, avoid these activities until you feel better.

Allergy

If you have a known allergy to linagliptin, metformin, or any other ingredients in Linaliglip M 2.5/500 Tablet 15, do not take this medicine. Inform your doctor about all your allergies before starting treatment.

Children

Caution is advised while giving Linaliglip M 2.5/500 Tablet 15 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Linaliglip M 2.5/500 Tablet 15 under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Linaliglip M 2.5/500 Tablet 15 interacts with the following medicines:

Carbonic Anhydrase Inhibitors: Medicines like topiramate and zonisamide may increase the risk of lactic acidosis when taken with Linaliglip M 2.5/500 Tablet 15.
Cationic Medicines: Medications such as cimetidine and ranolazine may compete with metformin for elimination through the kidneys, potentially increasing metformin levels in the blood.
Antiviral Medicines: Medicines like dolutegravir may affect how metformin works in your body, potentially leading to changes in blood sugar control.

Drug-Disease Interactions

Linaliglip M 2.5/500 Tablet 15 interacts with the following diseases:

Kidney Disease: Patients with severe kidney problems (eGFR below 30 mL/min) should not take this medicine, as it increases the risk of lactic acidosis.
Liver disease: This medicine should be used cautiously in patients with liver problems, as it may affect how the medicine is processed.
Pancreatitis: Patients with a history of pancreatitis should use this medicine cautiously, as linagliptin may increase the risk of pancreatic inflammation.
Heart Failure: People with heart failure may have an increased risk of lactic acidosis when taking metformin-containing medicines.

Daily Dose

The daily dose of Linaliglip M 2.5/500 Tablet 15 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as your response to treatment. It is important to follow the prescribed dosage without altering it.

Over Dose

Overdosing on Linaliglip M 2.5/500 Tablet 15 may cause stomach problems, headache, and low blood sugar (hypoglycaemia). You might feel dizzy, sweaty, confused, or unusually tired. Contact your doctor if you suspect an overdose.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed one and resume your regular schedule. Never take a double dose to make up for the missed one.

Store at room temperature below 30°C.
Protect from moisture and excessive heat.
Keep in its original packaging until ready to use.
Store in a dry place away from direct sunlight.
Keep out of reach of children.
Do not use after the expiry date printed on the package.

Follow a low-carbohydrate diet with plenty of vegetables, whole grains, and lean proteins to help maintain stable blood glucose (sugar) levels throughout the day.
Engage in regular physical activity, such as 30 minutes of brisk walking five days a week, which improves insulin sensitivity (how well your body responds to insulin) and helps control your blood sugar.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes, hyperglycaemia
Drug Category	DPP-4 inhibitor, Biguanide
Therapeutic Category	Anti-diabetic medication

Can I take Linaliglip M 2.5/500 Tablet 15 with other diabetes medicines?

Yes, but with caution. It may increase the risk of hypoglycaemia (low blood sugar). Your doctor will adjust your doses accordingly.

How long does it take for Linaliglip M 2.5/500 Tablet 15 to start working?

You may notice initial effects within days, but full benefits typically take several weeks as the medicine gradually improves your body's glucose control.

Can I stop taking Linaliglip M 2.5/500 Tablet 15 if my blood sugar normalises?

No. Continue taking it unless your doctor advises otherwise. Stopping suddenly can cause blood sugar levels to rise dangerously.

What should I do if I miss a dose?

Take it as soon as you remember. If it is nearly time for your next dose, skip the missed one. Never take a double dose.

Will Linaliglip M 2.5/500 Tablet 15 cause weight gain?

Unlike some diabetes medicines, this combination typically does not cause significant weight gain and may even support modest weight management.

Can I drink alcohol while taking this medicine?

No. Alcohol increases your risk of lactic acidosis (dangerous acid buildup) and hypoglycaemia when taking metformin-containing medicines.

How should I store Linaliglip M 2.5/500 Tablet 15?

Keep at room temperature (below 30°C) in a dry place away from moisture and direct sunlight. Store safely out of children's reach.

Last Updated On 06 Jun. 2025 | 3:26PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 13 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

Expiry on or after: February 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (n.d.). Linagliptin. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a611036.html (Accessed 1 April 2025)
MedlinePlus. (n.d.). Metformin. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a696005.html (Accessed 1 April 2025)
U.S. Food and Drug Administration. (2023). TRADJENTA
(linagliptin tablets), for oral use: Highlights of prescribing information. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/201280s027lbl.pdf (Accessed 1 April 2025)
DrugBank. (n.d.). Linagliptin. https://go.drugbank.com/drugs/DB08882 (Accessed 1 April 2025)
Corcoran, C., & Jacobs, T. F. (2023, August 17). Metformin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK518983/

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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