Prefilled syringe of 0.4 ML
Old MRP ₹3653.25
MRP ₹3424.92
₹2739.94
₹8562.3/ML
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Prescription required for this medicine
Store in refrigerator or (2o - 8o C) Do Not Freeze
CompositionCresp 40 Prefilled Syringe is used to treat anaemia associated with chronic kidney disease by stimulating red blood cell production. It helps improve energy levels and reduce weakness caused by low haemoglobin.
This medicine may also be used in chemotherapy-related anaemia. It should be administered as directed by your doctor. Inform them about existing conditions and report side effects during treatment.
Cresp 40 Prefilled Syringe is used to treat anaemia by stimulating red blood cell production. It is prescribed for adults and children with chronic kidney disease, including those undergoing dialysis as well as those not on dialysis. The injection is also used to reduce anaemia associated with myelosuppressive chemotherapy in adults with non-myeloid cancers and supports continued chemotherapy treatment by improving haemoglobin levels.
Administer Cresp 40 Prefilled Syringe as follows:
Cleanse the injection site on your upper arm, thigh or abdomen.
Follow your doctor's instructions to administer this medicine subcutaneously (under the skin).
Intravenous injections may be used for adult chronic kidney disease patients upon doctor's advice.
After use, dispose of the prefilled syringe safely to prevent accidental needle sticks.
Check the package for further details.
For more specific instructions, consult your doctor.
Cresp 40 Prefilled Syringe is administered subcutaneously.
Cresp 40 Prefilled Syringe may cause side effects such as high blood pressure, headache, joint pain, muscle spasms, diarrhoea, and pain at the injection site. If these side effects persist, consult your doctor.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Cresp 40 Prefilled Syringe. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are a couple of suggestions for managing common side effects:
Diarrhoea: Try to administer Cresp 40 Prefilled Syringe after having food.
Headache: If this medicine causes you a headache, consider administering it just before you go to bed at night.
Cresp 40 Prefilled Syringe contains Darbepoetin Alfa (0.04 MG) which works in your body as follows:
Stimulates Red Blood Cell Production: Darbepoetin alfa is a man-made type of erythropoietin, a hormone naturally produced by your kidneys. This hormone stimulates the production of red blood cells in your bone marrow.
Increases Oxygen-Carrying Capacity: By increasing red blood cell levels, darbepoetin alfa improves the oxygen-carrying capacity of your blood. This helps alleviate symptoms like fatigue and shortness of breath associated with anaemia.
Activates Erythropoietin Receptors: Darbepoetin alfa binds to and activates erythropoietin receptors on red blood cell precursors in your bone marrow. This activation promotes the survival, proliferation, and differentiation of these precursor cells into mature red blood cells.
Caution is advised while administering the Cresp 40 Prefilled Syringe if you are pregnant. It is best to consult your doctor before starting this medicine.
If you are breastfeeding, make sure to discuss this with your doctor before starting Cresp 40 Prefilled Syringe.
The interaction of Cresp 40 Prefilled Syringe with alcohol is unknown. Discuss your drinking habits with your doctor before using this medication.
If you have liver problems, discuss them with your doctor before starting Cresp 40 Prefilled Syringe. This medicine may affect liver function.
Consult your doctor before administering the Cresp 40 Prefilled Syringe if you have a history of any kidney problems.
Cresp 40 Prefilled Syringe may cause dizziness or fatigue. If affected, avoid driving or operating heavy machinery.
If you have latex allergy, proceed with caution as the prefilled syringes contain dry natural rubber. Always inform your doctor about any allergies before beginning with this medicine.
Cresp 40 Prefilled Syringe is not recommended for children under the age of 18 years. Always consult your doctor before giving any medicine to a child.
Older patients should administer the Cresp 40 Prefilled Syringe under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Cresp 40 Prefilled Syringe interacts with the following medicines:
Corticosteroids: When administered with corticosteroids such as prednisone Cresp 40 Prefilled Syringe could increase fluid retention, leading to swelling or edema.
Certain dietary habits can affect how Cresp 40 Prefilled Syringe works:
High Potassium Foods: Consuming foods high in potassium, such as bananas or sweet potatoes, while on this medication could potentially affect the balance of electrolytes in your body.
Cresp 40 Prefilled Syringe interacts with the following diseases:
Hypertension: If you have high blood pressure, this medicine could potentially exacerbate your condition.
Seizure Disorders: People with seizure disorders should be cautious as it could interfere with their condition or medication.
Heart Disease: If you've had a heart attack or stroke, or if you have heart failure, using this medicine could potentially pose additional risks.
Your doctor will prescribe the daily dose of Cresp 40 Prefilled Syringe. This prescription will be based on your health condition and how you respond to the medication. Always adhere to your doctor's instructions and avoid altering the dosage without consulting them. For detailed information, please refer to the package insert.
Excessive use of Cresp 40 Prefilled Syringe may lead to an escalation in side effects such as headaches, joint pain, muscle spasms, and high blood pressure. If you suspect an overdose, inform your doctor promptly.
If you forget to administer your scheduled dose of Cresp 40 Prefilled Syringe, do it as soon as you remember. However, if it's nearly time for your next dose, skip the forgotten one and continue with your regular schedule. Never administer extra doses without consulting your doctor.
Store your Cresp 40 Prefilled Syringe between 2°C and 8°C, in a cool and dry place.
Avoid exposing it to direct sunlight or moisture.
Keep it out of reach and sight of children.
Engage in regular light exercise as it can help improve fatigue and weakness associated with anaemia.
Maintain a diet rich in iron, like leafy greens and lean meats. This supports red blood cell production, complementing the effects of Cresp 40 Prefilled Syringe.
| Available Dosage Types | Prefilled Syringe |
| Habit Forming | No |
| Ailment | Chronic Kidney Disease, Chemotherapy-Induced Anaemia |
| Drug Category | Erythropoiesis-Stimulating Agent |
| Therapeutic Category | Anaemia Management |
Yes, this medicine is designed for self-administration. However, you should first receive proper training from your doctor.
If you miss a dose, administer it as soon as possible and consult your doctor for further instructions.
Store it between 2°C to 8°C, away from light. Don't freeze or shake it. It can be at room temperature for up to 7 days.
You may see an increase in your haemoglobin levels between 2 to 6 weeks after starting this medicine.
No, only your doctor should adjust the dose based on lab results and your clinical condition
Common side effects include high blood pressure, headache, joint pain, muscle spasms, diarrhoea, and injection site pain. Please consult the doctor if they persist.
Used syringes should go in puncture-resistant containers like laundry detergent bottles. Follow local regulations for disposal.
Check out Editorial Policy
Darbepoetin alfa: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00012
Darbepoetin alfa. (n.d.-b). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1276633/
Darbepoetin Alfa Injection: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a604022.html
Ibbotson, T., & Goa, K. L. (2001). Darbepoetin Alfa. Drugs, 61(14), 2097–2104. https://pubmed.ncbi.nlm.nih.gov/11735636/
Tani, J., Ito, Y., Tatemichi, S., Yamakami, M., Fukui, T., Hatano, Y., Kakimoto, S., Kotani, A., Sugimura, A., Mihara, K., Yamamoto, R., Tanaka, N., Minami, K., Takahashi, K., & Hirato, T. (2020). Physicochemical and biological evaluation of JR-131 as a biosimilar to a long-acting erythropoiesis-stimulating agent darbepoetin alfa. PloS one, 15(4), e0231830. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164597/
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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