Advagraf 1mg 5 Pack Of 10 Capsules

Advagraf 1mg Capsule 50 is used for the following health conditions:

• Preventing organ rejection in liver and kidney transplant patients.
• Preventing organ rejection in heart transplant patients.

To use Advagraf 1mg Capsule 50 correctly, follow these instructions:

• Swallow the capsule whole with a glass of water.
• Do not break, crush, or chew the capsule.
• Always take this medicine as prescribed by your doctor.
• Consult your doctor for specific advice tailored to your health condition and medication schedule.

Advagraf 1mg Capsule 50 is taken orally.

Advagraf 1mg Capsule 50 contains tacrolimus (1 mg), which contributes to its action in your body as follows:

• Binding with FKBP-12: Tacrolimus forms a complex with an intracellular protein called FKBP-12.
• Inhibiting Calcineurin: The tacrolimus-FKBP-12 complex then inhibits a calcium-dependent enzyme called calcineurin.
• Suppressing T Cell activation: By inhibiting calcineurin, tacrolimus suppresses the activation of T cells, which are crucial components of the immune system.
• Reducing Cytokine gene expression: The suppression of T cell activation leads to a reduction in cytokine gene expression. Cytokines are proteins that play a pivotal role in cell signalling during immune responses.
• Preventing organ rejection: By suppressing immune reactions at the cellular level, tacrolimus helps prevent the body from rejecting transplanted organs.

• Store Advagraf 1mg Capsule 50 in a cool, dry place at a temperature below 30°C.
• Don't expose the medicine to excessive light or moisture.
• Keep it out of reach of children.
• Always use this medicine before its expiry date.

• Since Advagraf 1mg Capsule 50 is used for managing organ rejection after transplantation, it's crucial to follow a balanced diet rich in proteins and low in salt and fat to support overall health and organ function.
• Remember to avoid exposure to sunlight and ultraviolet light, as this medicine increases your risk of skin cancer. Wear protective clothing and use sunscreen when outdoors.