Zydus Lifesciences Limited
Strip of 10 Units
Old MRP ₹462.8
MRP ₹433.88
₹347.1
₹43.39/Units
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CompositionTacromus 1 Capsule 10 is used to prevent organ rejection in transplant patients and treat autoimmune disorders by suppressing the immune system. It helps the body accept the transplanted organ.
Consult your doctor about the correct dosage and schedule. Inform them about other medications or health conditions you may have. If side effects occur, notify your doctor immediately and continue the medicine as prescribed.
Tacromus 1 Capsule 10 is used to prevent organ rejection in patients who have undergone organ transplants, such as liver, kidney, or heart transplants. It helps the body accept the new organ by modulating immune responses, thus improving long-term transplant outcomes.
To use Tacromus 1 Capsule 10 correctly, follow these instructions:
Swallow the capsule whole with a glass of water.
Do not break, crush, or chew the capsule.
Always take this medicine as prescribed by your doctor.
Consult your doctor for specific advice tailored to your health condition and medication schedule.
Tacromus 1 Capsule 10 is taken orally.
Tacromus 1 Capsule 10 may cause diarrhea, hypertension, nausea, constipation, abdominal pain, and tremors (involuntary muscle contractions leading to shaking movements).
Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Tacromus 1 Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are some general guidelines for managing common side effects:
Diarrhoea: Try taking Tacromus 1 Capsule 10 with food or milk to lessen this effect.
Nausea: If you feel nauseated, consider taking this medicine after meals to reduce discomfort.
Tacromus 1 Capsule 10 contains tacrolimus (1 mg), which contributes to its action in your body as follows:
Binding with FKBP-12: Tacrolimus forms a complex with an intracellular protein called FKBP-12.
Inhibiting Calcineurin: The tacrolimus-FKBP-12 complex then inhibits a calcium-dependent enzyme called calcineurin.
Suppressing T Cell activation: By inhibiting calcineurin, tacrolimus suppresses the activation of T cells, which are crucial components of the immune system.
Reducing Cytokine gene expression: The suppression of T cell activation leads to a reduction in cytokine gene expression. Cytokines are proteins that play a pivotal role in cell signalling during immune responses.
Preventing organ rejection: By suppressing immune reactions at the cellular level, tacrolimus helps prevent the body from rejecting transplanted organs.
According to animal studies, Tacromus 1 Capsule 10 may cause harm to the developing baby. If you are pregnant, it's best to consult your doctor before taking this medicine.
Tacrolimus, the active ingredient in Tacromus 1 Capsule 10, is present in human milk and can have serious adverse effects on nursing infants. It's advised not to breastfeed while taking this medicine.
There is no specific information available about the interaction of Tacromus 1 Capsule 10 with alcohol. However, caution is always advised. Consult your doctor if you have any concerns.
Tacromus 1 Capsule 10 is metabolised by the liver. If you have liver health issues, discuss them with your doctor before starting this medicine.
This medicine can affect kidney function. Caution is advised before using Tacromus 1 Capsule 10 if you have a history of kidney problems. It's best to consult your doctor before taking this medicine.
No specific information is available about the impact of Tacromus 1 Capsule 10 on your ability to drive or operate machinery. Always be cautious, and if you feel unwell or dizzy, avoid these activities.
Tacromus 1 Capsule 10 should not be taken if you are allergic to tacrolimus or any other component of the product. If you have any known allergies, discuss them with your doctor before starting this medicine.
The safety and efficacy of Tacromus 1 Capsule 10 have been established for certain transplant patients from the age of 2 years. However, caution is advised while giving this medicine to children under 18 years of age. Always consult your doctor before giving any medicine to a child.
No significant differences have been observed between elderly and younger patients using Tacromus 1 Capsule 10. However, older patients should take this medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.
Tacromus 1 Capsule 10 interacts with the following medicines:
CYP3A4 inhibitors: Medicines like bromocriptine, clarithromycin, and diltiazem can increase tacrolimus blood levels, potentially aggravating side effects.
CYP3A4 inducers: Medicines such as carbamazepine, phenobarbital, and rifampin can decrease tacrolimus levels, potentially reducing its effectiveness.
Certain foods may interact with Tacromus 1 Capsule 10:
Grapefruit juice: Consuming grapefruit juice while taking this medicine may increase tacrolimus levels in the blood, potentially enhancing side effects.
Tacromus 1 Capsule 10 interacts with the following diseases:
Hypertension: High blood pressure may worsen when taking this medicine due to its potential to cause elevated blood pressure.
Diabetes: This medication could affect blood sugar control, necessitating close monitoring of glucose levels.
Liver disease: Liver function may affect how this medicine works. Therefore, individuals with liver disease should use it cautiously.
Your doctor will prescribe the exact daily dosage of Tacromus 1 Capsule 10 based on your individual needs. Factors such as the severity of your condition and your response to treatment will be considered. Always follow the prescribed dosage and never exceed it without consulting your doctor. For further details regarding dosage, read the package insert.
In case of an overdose, you may experience symptoms such as headache, shaking, or changes in mental status. If you have taken more than the prescribed dose of Tacromus 1 Capsule 10, do not panic but inform your doctor about it.
If you forget to take a dose of Tacromus 1 Capsule 10, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular dosage schedule. Never increase your dosage without consulting your doctor.
Store Tacromus 1 Capsule 10 in a cool, dry place at a temperature below 30°C.
Don't expose the medicine to excessive light or moisture.
Keep it out of reach of children.
Always use this medicine before its expiry date.
Since Tacromus 1 Capsule 10 is used for managing organ rejection after transplantation, it's crucial to follow a balanced diet rich in proteins and low in salt and fat to support overall health and organ function.
Remember to avoid exposure to sunlight and ultraviolet light, as this medicine increases your risk of skin cancer. Wear protective clothing and use sunscreen when outdoors.
| Available Dosage Types | Capsule |
| Habit Forming | No |
| Ailment | Organ Rejection Prophylaxis |
| Drug Category | Calcineurin Inhibitor |
| Therapeutic Category | Immunosuppressant |
Tacromus 1 Capsule 10 is an immunosuppressant medicine that contains tacrolimus. It helps to prevent organ rejection in adults who have had a transplant.
It works by reducing the activity of your immune system, specifically T lymphocytes, to prevent it from attacking the transplanted organ.
Take the capsule as prescribed by the doctor. Remember to swallow it whole without chewing or crushing it.
Food can decrease the rate at which tacrolimus is absorbed into your body. Consult your doctor for personalised advice on when to take it.
Limit exposure to sunlight and UV light, monitor your blood glucose levels and blood pressure, and avoid live vaccines while taking this medicine.
Yes, common side effects include abnormal kidney function, high blood pressure, nausea, tremors, constipation and headaches, among others. Consult your doctor if the side effects persist.
Yes, it can interact with many medicines such as bromocriptine, clarithromycin, erythromycin, and carbamazepine. Always consult your doctor before starting any new medication.
Check out Editorial Policy
MedlinePlus. (n.d.). Tacrolimus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a601117.html
U.S. Food and Drug Administration. (2018). Clinical Pharmacology and Biopharmaceutics Review(s). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/210115Orig1s000ClinPharmR.pdf
Iwasaki K: Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics. Drug Metab Pharmacokinet. 2007 Oct;22(5):328-35. https://go.drugbank.com/articles/A38786
Tacrolimus.
U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050709s031lbl.pdf
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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