Crema Gel is used to manage anal fissures and the discomfort associated with small tears in the anal lining. It works by relaxing the smooth muscles around the anus and improving localized blood flow. This action helps reduce the intense pain often felt during bowel movements and creates an environment that supports natural tissue healing.
The active ingredient, Diltiazemacts as a local vasodilator, which helps reduce the pressure within the anal canal. By easing this pressure, the gel significantly reduces the risk of further tearing and helps alleviate the cycle of pain and muscle spasms. It is a critical component of non-surgical management for chronic and acute anal fissures, providing targeted relief where it is needed most.
Apply the gel only as advised by your doctor, typically using a small amount on the affected area. Follow the recommended duration of treatment to ensure complete healing of the fissure. If you experience persistent headaches, localized irritation, or any unusual symptoms, inform your doctor promptly to adjust your treatment plan.
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Cremagel Gel 30gm
Tube of 30 GM
Old MRP ₹279.44
MRP ₹261.97
₹209.58
₹8.73/GM
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CompositionAbout Cremagel Gel 30gm
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Uses of Cremagel Gel 30gm
Crema Gel is used to support healing of anal fissures by relaxing smooth muscles and improving blood flow around the anal region. It is also used to reduce pain, itching, and irritation at the affected site while aiding tissue repair and lowering pressure within anal tissues.
Directions for Use of Cremagel Gel 30gm
- Apply Cremagel 2% Gel gently inside and around the anus with a small amount on your finger or as your doctor instructs.
- Cremagel 2% Gel is solely for external use. Before and after applying, wash your hands. Wrap your fingers with cling film or a disposable glove to apply the medication. After use, throw away the finger covering.
- Keep Cremagel 2% Gel away from your mouth, ears, nose, eyes, and vagina.
- To achieve the best results, continue using Cremagel 2% Gel for the term your doctor prescribes without interruption.
Route of Administration
Cremagel 2% Gel is a medication administered topically, directly to the skin, typically to the area around the anal fissure.
Side Effects of Cremagel Gel 30gm
Crema Gel may cause local skin reactions, such as itching, burning, and redness, at the application site. These side effects are usually mild and resolve on their own; however, if they persist or worsen, please contact your healthcare provider.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing Cremagel 2% Gel. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
How Cremagel Gel 30gm Works?
- Cremagel 2% Gel is a topical medication used to treat anal fissures. The active ingredient in Cremagel 2% Gel is Diltiazem hydrochloride, which belongs to a class of medications known as calcium channel blockers.
- Calcium channel blockers block the influx of calcium ions into smooth muscle cells, including those in the anal sphincter. By minimising the concentration of calcium ions in these cells, Cremagel 2% Gel causes the muscle fibres to relax, reducing pressure on the anal fissure and promoting healing.
- Additionally, Cremagel 2% Gel has been shown to decrease anal sphincter pressure, which can help to reduce further pain and discomfort associated with anal fissures.
Safety Measures & Warnings
Pregnancy
Use of Cremagel 2% Gel in pregnancy is recommended only if the potential benefit exceeds the potential risk to the fetus. According to the FDA, no adequate and well-controlled studies on pregnant women exist. It is recommended to discuss the risks and benefits of using Cremagel 2% Gel during pregnancy with a healthcare provider before using it.
Breastfeeding
Cremagel 2% Gel is not recommended during breastfeeding. It is unknown whether diltiazem is excreted in human milk, and there is a risk of adverse effects on the nursing infant. It is recommended to avoid breastfeeding while using Cremagel 2% Gel.
Alcohol
It is advised to avoid alcohol consumption while using Cremagel 2% Gel. Alcohol may increase the risk of dizziness and drowsiness associated with diltiazem.
Liver
Patients with liver problems should use Cremagel 2% Gel with caution. Diltiazem is metabolised in the liver, and impaired liver function may affect drug metabolism and increase the risk of adverse effects. Patients with liver problems should be closely monitored for side effects using Cremagel 2% Gel.
Kidney
Patients with kidney problems should use Cremagel 2% Gel with caution. Diltiazem is excreted mainly through the kidneys, and impaired kidney function may affect drug clearance and increase the risk of adverse effects. Patients with kidney problems should be closely monitored for side effects using Cremagel 2% Gel.
Use In Driving And Operating Machinery
Cremagel 2% Gel may cause dizziness, drowsiness, or blurred vision, affecting the ability to operate machinery or drive a vehicle. Patients should avoid operating machinery or driving until they know how Cremagel 2% Gel affects them.
Allergy
Patients with a known allergy to diltiazem should not use Cremagel 2% Gel. Allergic reactions to diltiazem may include rash, itching, swelling, dizziness, and difficulty breathing. Patients should inform their healthcare provider if they experience any symptoms of an allergic reaction.
Children
The safety and effectiveness of Cremagel 2% Gel in children have not been established. Therefore, it is not suggested for use in children.
Older Patients
Older people may be more susceptible to the side effects of Cremagel 2% Gel. The dose may be required to be adjusted in older patients, and they should be closely monitored for side effects while using Cremagel 2% Gel.
Interactions of Cremagel Gel 30gm
Drug-Drug Interactions
Cremagel 2% Gel can interact with other medications, leading to adverse effects or reduced efficacy. It is essential to inform your doctor about all medications, supplements, and herbal products before using Cremagel 2% Gel.
Here are some examples of drug-drug interactions that may occur with Cremagel 2% Gel:
- Salmeterol, Formoterol, and Budesonide medicines are used to treat asthma.
- Aspirin, Naproxen and Ibuprofen medicines are used to relieve pain.
- Atenolol and metoprolol are medicines used to treat blood pressure.
- Diphenhydramine and loratadine are medicines used to treat allergies.
- Lidocaine - Anaesthetic - medicines used to induce anaesthesia.
- Digoxin - Medicines used to treat heart failure increased digoxin levels in the blood, potentially leading to toxicity.
- Alprazolam -Medicines used to treat anxiety.
Drug-Disease Interactions
Drug-Disease Interactions
Cremagel 2% Gel can interact with several diseases, and caution is advised when using Cremagel 2% Gel in patients with certain medical conditions. Here are some drug-disease interactions that may occur with Cremagel 2% Gel:
- Heart failure: Cremagel 2% Gel should be used cautiously in patients with heart failure. This medication can cause a negative inotropic effect, reducing the strength of the heart's contractions. This can worsen heart failure symptoms and lead to complications.
- Bradycardia: Cremagel 2% Gel can cause a decrease in heart rate, which can worsen pre-existing bradycardia (slow heart rate).
- Liver disease: Cremagel 2% Gel is metabolised by the liver, and caution is advised when using this medication in patients with liver disease. This medication can cause an increase in liver enzymes, which can indicate liver damage.
- Kidney disease: Cremagel 2% Gel is excreted by the kidneys, and caution is advised when using this medication in patients with kidney disease. This medication can cause an increase in creatinine levels, which can indicate kidney damage.
- Hypotension: Cremagel 2% Gel can cause a decrease in blood pressure, which can lead to hypotension (low blood pressure).
Dosage of Cremagel Gel 30gm
Daily Dose
The recommended daily dose of Cremagel 2% Gel is topically around the anus once a day. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is essential to follow the prescribed dose and not exceed it without consulting your doctor.
Over Dose
If you or someone else accidentally apply excessive Cremagel 2% Gel, it is essential to take immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include itching and burning sensation on the applied area, bleeding, dizziness, fainting, irregular heartbeat, confusion, and increased sweating and fits.
Missed Dose
If you forgot to apply Cremagel 2% Gel, apply it as soon as you remember. If the time for the upcoming dosage is close, skipping the missed one is recommended, and resuming your regular dosage pattern. Never increase your dosage without consulting your doctor.
Storage
- Store this medicine at room temperature (15-25ºC).
- Please protect it from light and moisture.
- Keep Cremagel 2% Gel away from children.
- Do not use Cremagel 2% Gel after the expiry date has passed.
Special Dietary And Lifestyle Recommendation
- Eat a healthy and balanced diet: A healthy and balanced diet can help improve overall health and manage certain medical conditions. Individuals using Cremagel 2% Gel should aim to consume a more fibre-rich diet, fruits, vegetables, whole grains, and lean protein.
- Limit alcohol consumption: Alcohol can interact with diltiazem and raises the risk of side effects, such as dizziness and lightheadedness. Therefore, it is recommended to limit alcohol consumption while using Cremagel 2% Gel.
- Exercise regularly: Regular exercise can help improve overall health and manage certain medical conditions. Individuals using Cremagel 2% Gel should aim to exercise regularly, with the guidance of their healthcare provider.
- Manage stress: Stress can impact overall health and worsen certain medical conditions. Therefore, individuals using Cremagel 2% Gel should aim to manage stress through meditation, deep breathing, or yoga.
- Exercise, extended standing, and prolonged sitting ought to be avoided.
- Drink more water, at least 7-8 glasses daily.
- Take daily relaxing baths or sitz baths for 10–20 minutes.
- Refrain from spending too much time sitting and straining on the toilet.
Quick Tips
- Cremagel 2% Gel is an external preparation that prevents contact with the mouth, eyes, nose, and ears. In the event of an accident, thoroughly rinse with water.
- Please avoid using this medication longer than prescribed, as it may raise the risk of side effects.
- Attend regular follow-up appointments with your healthcare provider to monitor your progress and ensure the medication works effectively.
Fact Box
| Dosage Forms Available | Topical gel |
| Habit Forming | No |
| Ailment | Anal fissures |
| Drug Category | Calcium channel blockers- Nondihydropyridines |
| Therapeutic Category | Anti haemorrhoid |
Frequently Asked Questions (FAQs)
Is Cremagel 2% Gel good for piles?
Cremagel 2% Gel is a topical gel that may temporarily relieve symptoms associated with piles, such as itching and pain, but it is not a cure for the underlying condition. It is best to consult a doctor for the proper diagnosis and treatment of piles.
Is Cremagel 2% Gel good for fissures?
Cremagel 2% Gel may temporarily relieve fissures symptoms, such as pain and itching, but it is not a cure for the underlying condition. It is recommended to consult a doctor for proper diagnosis and treatment of fissures.
How many times should I apply crema gel?
As directed by your healthcare provider, apply a small amount of Cremagel 2% Gel to the afflicted region once daily. Use Cremagel 2% Gel only after talking to your doctor. Wash your hands both before and after use.
Is Crema gel effective?
Cremagel 2% Gel repairs anal fissures well when diltiazem relaxes the muscles surrounding the anus. (back passage). This action decreases pressure in the anal areas and enhances blood flow, which aids anus wound healing.
When do you use crema gel?
Cremagel 2% Gel is a topical gel that can relieve symptoms associated with minor skin irritations such as itching, burning, and rashes. It is best to consult a doctor before using Cremagel 2% Gel for any specific condition or medical concern.
What is the composition of Cremagel 2% Gel?
Cremagel 2% Gel is a medication that contains diltiazem as the main active ingredient.
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Country of origin: INDIA
References
- Akira Tsunoda, Yasuharu Kashiwagura, Ken-ichi Hirose, Tadanori Sasaki and Nobuyasu Kano. Quality of life in patients with chronic anal fissure after topical treatment with diltiazem. NIH National Library of Medicine. National center for Biotechnology Information. PMC PubMed Central. November 2012 [Accessed on 28th April 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596506/
- St. Mark’s Hospital. National Health Service (NHS). London Northwest University Healthcare. NHS trust. [Revised in December 2019]. [Accessed on 28th April 2022] https://www.stmarkshospital.nhs.uk/wp-content/uploads/2020/02/2112-diltiazem-2162009.pdf
- Chesterfield Royal Hospital. NHS foundation trust. Diltiazem 2% hydrochloride cream. [Revised in August 2019] [Accessed 28th April 2022] https://www.chesterfieldroyal.nhs.uk/application/files/8815/4142/8195/Diltiazem_2_Hydrochloride_Cream.pdf
- Diltiazem Hydrochloride 2% Cream. GIG CYMRU NHS Wales. Sian Elin Jones, Clinical Pharmacist. NHS.Uk. [Revised in September 2011]. [Accessed on 3rd November 2022] https://www.wmic.wales.nhs.uk/wp-content/uploads/2016/09/diltiazem_eng_PIL.pdf
- Hemorrhoid Centers of America. Alan L. Goldman, MD, FACS. Patient Drug Education for Diltiazem gel. March 2014. [Accessed on 3rd November 2022] https://hemorrhoidcentersamerica.com/wp-content/uploads/diltiazemgel.pdf
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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