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Atorvastatin + Metformin

Uses of Atorvastatin + Metformin

  • Atorvastatin + Metformin is used to manage high cholesterol (hyperlipidemia) and blood sugar levels in patients with type 2 diabetes. It belongs to the statins group and anti-diabetic medications.

  • This combination of Atorvastatin + Metformin is also beneficial in reducing the risk of heart attack, stroke, and cardiovascular diseases and in decreasing the kidney damage associated with diabetes.

Side effects of Atorvastatin + Metformin

  • Diarrhoea

  • Nausea and vomiting

  • Abdominal pain

  • Headache

  • Muscle pain or weakness

How Atorvastatin + Metformin works

  • Atorvastatin + Metformin is an anti-hyperlipidemic and anti-diabetic combination.

  • Atorvastatin is a statin. It reduces cholesterol production in the liver by blocking an enzyme called HMG-CoA reductase, thereby bringing down total cholesterol, bad cholesterol (LDL), and triglycerides while increasing the good cholesterol (HDL).

  • Metformin is an oral anti-diabetic medication. It controls blood sugar by decreasing glucose production in the liver, increasing insulin sensitivity, which allows body cells to use insulin more effectively, and reducing glucose absorption from the intestines.

  • Atorvastatin and Metformin work in unison to control blood sugar levels and lipid profile. This helps reduce the risk of cardiovascular complications in patients with type 2 diabetes and high cholesterol.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Meenakshi Maruwada
Dr. Meenakshi Maruwada Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Expert Advice

Dosage Forms Available

  • Atorvastatin + Metformin is available for oral administration in the form of tablets.

Age and Dose Restrictions

  • This combination is meant for adults and children above the age of 10 years.

Contraindications

  • Atorvastatin + Metformin is contraindicated in patients with known hypersensitivity to atorvastatin, metformin, or any component of the formulation.

  • It should not be used in patients with active liver disease or unexplained persistent elevations in liver enzymes.

  • The combination is also contraindicated in patients with severe renal impairment.

Other Medications to Avoid

  • This combination may interact with antibiotics (such as erythromycin and clarithromycin), antifungal medications (like itraconazole and ketoconazole), human immunodeficiency virus (HIV) protease inhibitors (such as ritonavir), medications used to suppress the immune system (like cyclosporine), and calcium channel blockers (such as diltiazem and verapamil).

  • It may also interact with antipsychotic medications (like topiramate and zonisamide), carbonic anhydrase inhibitors (like acetazolamide), medicines used to treat chest pain or angina (like ranolazine), antiretroviral medicines (like dolutegravir and vandetanib), and heartburn medication (like cimetidine).

Overdose and Missed Dose

  • An overdose of Atorvastatin + Metformin can lead to serious symptoms such as muscle weakness, abdominal pain, rapid breathing, and a slow or irregular heartbeat. If you suspect an overdose, seek immediate medical attention.

  • If you miss a dose of Atorvastatin + Metformin, take it as soon as you remember. However, if it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double your dose to make up for the missed one.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of fluids may help manage side effects like diarrhoea and nausea.

  • Taking the medication with or after meals can help reduce gastrointestinal side effects.

Use in Driving and Operating Machinery

  • Atorvastatin + Metformin may cause dizziness or lightheadedness. If you experience these symptoms, avoid driving or operating machinery until you feel well again.

Use in Pregnancy and Lactation

  • Atorvastatin + Metformin is not recommended during pregnancy unless prescribed by a doctor.

  • The medicine can pass into breast milk, so its use is discouraged during breastfeeding.

Caution in Other Conditions

  • People with a history of liver or kidney disease should take Atorvastatin + Metformin with caution. Diabetic patients who frequently consume alcohol should also be cautious while taking this medicine.

Special Dietary and Lifestyle Recommendations

  • Regular monitoring of blood glucose levels will help track the effectiveness of the medication and manage diabetes better.

  • A diet rich in fruits, vegetables, whole grains, lean meats, and low-fat dairy products can help manage diabetes and cholesterol levels.

  • Regular physical activity can help control blood glucose levels and maintain a healthy weight.

Frequently asked questions

No, Atorvastatin + Metformin is not a steroid. Atorvastatin belongs to the group of medicines called statins, which are used to lower cholesterol levels in the blood. Metformin is an anti-diabetic medication.

There is no direct evidence to suggest that Atorvastatin + Metformin affects sleep. However, sleep disturbances are not a common side effect of these medications. If you experience sleep problems while taking this medication, please consult your doctor.

There is no clear evidence to suggest that Atorvastatin + Metformin affects fertility in men or women. However, if you have concerns about fertility, it is recommended that you speak with your doctor.

Atorvastatin does not typically result in weight gain. However, Metformin can sometimes result in slight weight loss in some patients, especially those who are overweight.

Yes, it is safe to take Atorvastatin + Metformin daily if your doctor prescribes it. This medication is generally prescribed for long-term use.

Atorvastatin starts reducing cholesterol within 2 weeks, with maximum effect seen at 4 weeks. Metformin takes about 2 weeks to show an anti-hyperglycemic effect, which peaks in 2-3 months.

The best time to take Atorvastatin + Metformin is as your doctor advises.

Terms & Conditions


Atorvastatin + Metformin in other salts

ASPIRIN + ATORVASTATINASPIRIN + ATORVASTATIN + CLOPIDOGRELATORVASTATINATORVASTATIN + CLOPIDOGRELATORVASTATIN + FENOFIBRATEDAPAGLIFLOZIN + METFORMINGLICLAZIDE + METFORMINGLIMEPIRIDE + METFORMINGLIMEPIRIDE + METFORMIN + PIOGLITAZONEGLIMEPIRIDE + METFORMIN + VOGLIBOSELINAGLIPTIN + METFORMINMETFORMINMETFORMIN + SITAGLIPTINMETFORMIN + VILDAGLIPTINMETFORMIN + VOGLIBOSEMETFORMIN + TENELIGLIPTINASPIRIN + ATORVASTATIN + RAMIPRILMETFORMIN + MYO INOSITOLATORVASTATIN + EZETIMIBEATORVASTATIN + CHOLINE FENOFIBRATEATORVASTATIN + RAMIPRILAMLODIPINE + ATORVASTATINMETFORMIN + PIOGLITAZONEATORVASTATIN + S-AMLODIPINEATORVASTATIN + VITAMIN D3 (CHOLECALCIFEROL)ATORVASTATIN + NICOTINIC ACIDATORVASTATIN + EZETIMIBE + FENOFIBRATEGLIBENCLAMIDE + METFORMINGLIPIZIDE + METFORMINALPHA LIPOIC ACID + METFORMINMETFORMIN + METHYLCOBALAMINGLICLAZIDE + METFORMIN + PIOGLITAZONEGLICLAZIDE + METFORMIN + VOGLIBOSEMETFORMIN + PIOGLITAZONE + VOGLIBOSEGLIBENCLAMIDE + METFORMIN + PIOGLITAZONEGLIBENCLAMIDE + METFORMIN + ROSIGLITAZONEACARBOSE + METFORMINATORVASTATIN + GLIMEPIRIDE + METFORMINMETFORMIN + ROSIGLITAZONEMETFORMIN + REPAGLINIDED CHIRO INOSITOL + L-METHYLFOLATE + METFORMIN + METHYLCOBALAMIN + MYO INOSITOLEMPAGLIFLOZIN + METFORMINMETFORMIN + NATEGLINIDEMETFORMIN + SAXAGLIPTINGLIMEPIRIDE + METFORMIN + ROSIGLITAZONEMETFORMIN + REMOGLIFLOZIN ETABONATEALOGLIPTIN + METFORMINMETFORMIN + REMOGLIFLOZIN ETABONATE + VILDAGLIPTINDAPAGLIFLOZIN + METFORMIN + SITAGLIPTINDAPAGLIFLOZIN + METFORMIN + VILDAGLIPTINGLIMEPIRIDE + METFORMIN + SITAGLIPTINDAPAGLIFLOZIN + GLIMEPIRIDE + METFORMINMETFORMIN + MYO-INOSITOL / INOSITOLMETFORMIN + PIOGLITAZONE + SITAGLIPTINMETFORMIN + PIOGLITAZONE + TENELIGLIPTINDAPAGLIFLOZIN + LINAGLIPTIN + METFORMIN
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