Atorvastatin + Ezetimibe + Fenofibrate is primarily used to lower high cholesterol and triglyceride levels in the blood and belongs to the group of lipid-lowering medicines.
This medicine combination also helps to increase HDL cholesterol levels in individuals with low HDL levels and is also used to manage severe hypertriglyceridemia and homozygous familial hypercholesterolemia (HoFH).
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Atorvastatin + Ezetimibe + Fenofibrate is a combination medicine that helps manage high cholesterol and triglyceride levels.
Atorvastatin belongs to a class of medicines known as HMG-CoA reductase inhibitors or statins. It works by reducing the amount of harmful LDL cholesterol produced by the liver. This helps lower your overall cholesterol levels.
Ezetimibe is a cholesterol absorption inhibitor. It functions in the small intestine, where it blocks the absorption of cholesterol. This means less cholesterol ends up in your bloodstream.
Fenofibrate is a type of fibrate. It promotes the breakdown of triglycerides, which are a type of fat, in your blood. This helps reduce the risk of developing complications such as heart disease.
The combined action of these three components lowers "bad" LDL cholesterol, raises "good" HDL cholesterol, and decreases triglycerides more effectively than any of these medicines alone.
Doctor of Medicine
BMS, FMC, MD Resident
Atorvastatin + Ezetimibe + Fenofibrate is available for administration through the oral route in the form of tablets or capsules.
This combination is suitable for use in adults, and children above 10 years of age.
The combination of Atorvastatin + Ezetimibe + Fenofibrate is contraindicated in people with active liver disease or severe liver damage.
It is also contraindicated in people with severe kidney impairment or pre-existing gallbladder disease.
This combination may interact with medicines like other fibrates (such as gemfibrozil), bile acid sequestrants (like cholestyramine), anticoagulants (such as warfarin), and HIV medications (like ritonavir).
Overdosing on this combination medicine may lead to severe liver damage, muscle damage, and pancreatitis. If you suspect an overdose, contact your doctor immediately.
If you miss a dose, take it as soon as you recall. If it is close to the time for your next dose, skip the missed dose and go back to your normal schedule. Do not double the dose.
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Headache can be managed by drinking plenty of fluids and taking rest.
Stomach pain or muscle aches can be eased by lying down and applying a warm compress to the affected area.
Atorvastatin + Ezetimibe + Fenofibrate may cause dizziness or fatigue. If you experience these side effects, avoid driving or operating machinery.
The use of this medicine is not recommended during pregnancy and breastfeeding. Consult your doctor before using this medicine if you are pregnant or nursing.
Patients with active liver disease, severe kidney disease, and history of gallbladder disease should exercise caution when taking Atorvastatin + Ezetimibe + Fenofibrate.
A diet low in saturated fats, trans fats, cholesterol, salt (sodium), and added sugars can help manage cholesterol levels.
Regular physical activity can help raise your high-density lipoprotein (HDL) cholesterol, the "good" cholesterol, and lower your low-density lipoprotein (LDL) cholesterol, the "bad" cholesterol.
Regularly monitor your blood cholesterol levels.
Frequently asked questions
No, Atorvastatin + Ezetimibe + Fenofibrate is not a steroid. This combination belongs to a group of medicines known as cholesterol-lowering medicines.
Atorvastatin + Ezetimibe + Fenofibrate is not associated with affecting sleep. However, if you notice any changes in your sleep patterns after starting this medicine, consult your doctor for advice.
Atorvastatin + Ezetimibe + Fenofibrate is not associated with impacting fertility. If you have concerns about this, it is advisable to discuss them with your doctor.
The safety of daily use of Atorvastatin + Ezetimibe + Fenofibrate will depend on your health condition and the doctor’s recommendation. Always follow the instructions given by your doctor regarding the frequency of use.
The time taken by Atorvastatin + Ezetimibe + Fenofibrate to start showing its effects may vary from person to person. Regular monitoring of your cholesterol levels will be necessary to assess the effectiveness of the treatment.
Atorvastatin + Ezetimibe + Fenofibrate is taken orally. The best time to take this medicine will be as directed by your doctor.
Common side effects of this combination do not include changes in appetite. However, if you experience unusual changes in your appetite while taking this medicine, consult your doctor.
Atorvastatin + Ezetimibe + Fenofibrate in other salts
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