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Atorvastatin + Choline Fenofibrate

Uses of Atorvastatin + Choline Fenofibrate

  • Atorvastatin + Choline Fenofibrate is primarily used to manage mixed dyslipidemia. This medicine belongs to the group of antilipemic agents that help in reducing cholesterol levels in the body.

  • Additionally, it is used to reduce the risk of cardiovascular events in type 2 diabetic patients with mixed dyslipidemia, and who have no history of coronary heart disease.

Side effects of Atorvastatin + Choline Fenofibrate

Common side effects of Atorvastatin + Choline Fenofibrate include:

  • Muscle pain

  • Joint pain

  • Upset stomach

  • Diarrhoea

  • Abdominal pain

How Atorvastatin + Choline Fenofibrate works

  • Atorvastatin + Choline Fenofibrate is a combination lipid-lowering medication.

  • Atorvastatin is a type of medicine known as a statin. It works by blocking HMG-CoA reductase, an enzyme involved in cholesterol production in your body. This leads to a reduction in low-density lipoprotein (LDL), often referred to as 'bad cholesterol', and a slight increase in high-density lipoprotein (HDL), the 'good cholesterol'.

  • Choline Fenofibrate is a fibrate derivative. It operates by triggering peroxisome proliferator-activated receptor alpha (PPAR-α) which helps regulate the genes involved in lipoprotein metabolism. Consequently, this reduces triglyceride synthesis, boosts fatty acid catabolism, and enhances the production of HDL cholesterol.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Atorvastatin + Choline Fenofibrate is available for use as oral tablets.

  • The route of administration for Atorvastatin + Choline Fenofibrate is oral.

Age and Dose Restrictions

  • This medicine is meant for use in adults.

  • It is not recommended for use in paediatric patients.

Contraindications

  • This medicine is contraindicated in patients with active liver disease.

  • This medicine is contraindicated in patients with severe renal impairment (CrCl <30 mL/min).

  • This medicine is contraindicated in patients with preexisting gallbladder disease.

Other Medications to Avoid

  • This combination may interact with antifungals (such as ketoconazole), anticoagulants (like warfarin), and bile acid sequestrants (such as cholestyramine).

Overdose and Missed Dose

  • An overdose of this medication may result in increased severity of side effects such as muscle pain or weakness, an indicator of potential rhabdomyolysis; urgent medical attention is required.

  • If you miss a dose of this medication, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If you experience mild digestive discomfort such as dyspepsia or diarrhoea, consider taking the medication with food.

  • Stay hydrated by drinking adequate water, especially if you experience diarrhoea.

Use in Driving and Operating Machinery

  • This medication can cause dizziness. Avoid driving or operating heavy machinery if you feel dizzy after taking this medication.

Use in Pregnancy and Lactation

  • Atorvastatin + Choline Fenofibrate is contraindicated in pregnancy and during breastfeeding. It may cause harm to the foetus and it is present in breast milk.

  • Always consult your doctor before using this medicine during pregnancy or while breastfeeding.

Caution in Other Conditions

  • Patients with mild to moderate renal impairment should start at lower doses due to the increased risk of adverse effects.

  • Extreme caution should be exercised by those with a history of liver disease, monitoring liver function regularly when using this medication.

Special Dietary and Lifestyle Recommendations

  • Adhere to a low-fat, low-cholesterol diet to assist in managing cholesterol levels effectively while using Atorvastatin + Choline Fenofibrate.

  • Incorporate regular physical activities such as walking, cycling, or swimming into your daily routine to improve cardiovascular health.

  • Avoid foods high in saturated fats and trans fats, such as fried foods, processed meats, full-fat dairy products, and certain oils like palm oil.

  • Increase the intake of soluble fibre from sources such as oats, fruits, vegetables, and legumes which can help reduce LDL cholesterol levels.

  • Consider incorporating fatty fish into your diet, which contains omega-3 fatty acids known to improve heart health by reducing triglycerides.

  • Limit the consumption of alcohol as it can raise triglyceride levels and contribute to liver health complications.

Frequently asked questions

While Atorvastatin + Choline Fenofibrate itself does not contain any animal-derived ingredients, the coatings for the tablets may sometimes include gelatine. If you are vegetarian or vegan, please consult your doctor for suitable alternatives.

While mood changes are not a commonly reported side effect of Atorvastatin + Choline Fenofibrate, individuals may react differently to medications. If you notice significant mood changes after starting this medication, please consult your doctor.

While certain lifestyle changes and natural remedies may help manage high cholesterol levels, they may not be as effective as Atorvastatin + Choline Fenofibrate in managing mixed dyslipidemia. Always consult your doctor before trying any alternative treatments.

There is no evidence suggesting that taking Atorvastatin + Choline Fenofibrate during menstruation can cause any adverse effects. However, if you notice any unusual symptoms, please consult your doctor.

No specific food interactions have been reported with Atorvastatin + Choline Fenofibrate. However, maintaining a balanced diet is important for managing cholesterol levels.

You should continue taking Atorvastatin + Choline Fenofibrate even if your cholesterol levels have normalised unless advised otherwise by your doctor. Discontinuing the medication may lead to a rise in cholesterol levels.

There are other combinations of lipid-lowering medications available, but the choice depends on individual patient factors. Always consult your doctor for the most appropriate medication for your condition.

Terms & Conditions


Available medicines for ATORVASTATIN + CHOLINE FENOFIBRATE
Fenotorva 10/135 MG Capsule 10
Fenotorva 10/135 MG Capsule 10
Zydus Cadila
Pack of 10 Units
₹161.95
MRP ₹197.50
18.00% OFF
Lipicure Cf 20/160 MG Capsule 10
Lipicure Cf 20/160 MG Capsule 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹151.41
MRP ₹184.65
18.00% OFF
Fenotorva 20/135 MG Capsule 10
Fenotorva 20/135 MG Capsule 10
Zydus Cadila
Pack of 10 Units
₹216.40
MRP ₹263.90
18.00% OFF
Lipicure Cf 10/160 MG Capsule 10
Lipicure Cf 10/160 MG Capsule 10
Intas Pharmaceuticals Ltd
Pack of 10 Units
₹138.58
MRP ₹169.00
18.00% OFF

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