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Atorvastatin

HYPOLIPIDEMIC DRUGS

Uses of Atorvastatin

  • Atorvastatin is used together with a proper diet to lower cholesterol and triglyceride (fat) levels in the blood.
  • It primarily reduces low-density lipoprotein (LDL) cholesterol while increasing high-density lipoprotein (HDL) cholesterol. The medication is prescribed to reduce the risk of stroke, heart attack, and other cardiovascular complications, especially in individuals with risk factors such as type 2 diabetes and coronary heart disease.
  • Atorvastatin treats various types of dyslipidemia, including primary hypercholesterolemia and mixed dyslipidemia, and helps slow the progression of atherosclerosis, a condition marked by the hardening and narrowing of arteries due to cholesterol and plaque buildup.

Side effects of Atorvastatin

The side effects of Atorvastatin are:

  • Nausea
  • Constipation 
  • Flatulence 
  • Diarrhoea 
  • Indigestion
  • Joint pain 
  • Muscle pain 
  • Back pain

How Atorvastatin works

  • Atorvastatin works by inhibiting an enzyme in the liver known as HMG-CoA reductase. Here’s a detailed explanation of its mechanism of action:
    Atorvastatin blocks the action of HMG-CoA reductase, an enzyme involved in the production of cholesterol in the liver. This enzyme is crucial for the conversion of HMG-CoA to mevalonate, a key step in the biosynthesis of cholesterol.
  • By inhibiting this enzyme, atorvastatin reduces the synthesis of cholesterol in the liver. This leads to a decrease in the overall level of cholesterol in the blood.
  • With reduced cholesterol synthesis, the liver cells increase the number of LDL receptors on their surface. These receptors bind to LDL cholesterol particles (often referred to as "bad cholesterol") and remove them from the bloodstream.

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Atorvastatin is available for use via the oral route (tablets, capsules).

Age and Dose Restrictions

  • Atorvastatin is meant for adults and children above 10 years of age.

Contraindications

  • Atorvastatin is contraindicated in patients with known allergies to atorvastatin and who have severe kidney or liver issues.

Other Medications To Avoid With This Medicine

  • Avoid using antibiotics, antifungals, HIV medications, hepatitis C medications, anti-arthritis medications, heart rate control medications, and antihypertensive medications while on Atorvastatin. Always consult your doctor before taking any prescription or over-the-counter medications.

Overdose and Missed Dose

  • In case of an overdose of Atorvastatin, inform your doctor and follow the advice accordingly.
  • If you forget an Atorvastatin dose, take it as soon as you remember. But avoid repeating the dose.

Use In Driving And Operating Machinery

  • Atorvastatin may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this combination.

Use in Pregnancy and Lactation

  • Atorvastatin is not recommended during pregnancy or breastfeeding.

Special Dietary & Lifestyle Recommendation

  • Avoid alcohol when you are taking Atorvastatin.
  • People dealing with a history of high cholesterol are advised to contemplate lifestyle adjustments, including dietary modifications such as adopting a low-cholesterol and low-fat diet along with Atorvastatin.
  • Avoid grapefruit juice when taking Atorvastatin as it can affect the working of atorvastatin.

Frequently asked questions

Atorvastatin starts showing its effect within a few hours after ingestion.

Notify your doctor of your use of Atorvastatin before any forthcoming surgical interventions or emergency hospital admissions, as it may elevate the potential for bleeding.

Do not stop taking it without consulting your doctor, even if you feel healthy.

Consult your doctor before taking this, if you have kidney or liver issues to ensure its safety and proper dosage.

Atorvastatin, commonly known as Lipitor, is a statin used to lower cholesterol levels. While some studies suggest a small increase in diabetes risk with statins, the absolute risk remains low. If you are concerned about the risk of getting diabetes, consult your doctor before you take this tablet.

Atorvastatin is not associated with weight loss. However, some people may experience changes in appetite while taking statins.

Atorvastatin is not a blood thinner. It works by lowering cholesterol levels and reducing the risk of heart attacks and strokes.

You can take atorvastatin either in the morning or at night. Consistency matters more than the specific time due to its long half-life.

Some studies suggest a link between statins (including atorvastatin) and memory issues, but this remains controversial. If you experience memory problems, consult your doctor.

Atorvastatin is generally not prescribed to children under 10 years of age.

Terms & Conditions


Available medicines for ATORVASTATIN
Biovas 10 Tablet 10
Biovas 10 Tablet 10
Biochem Pharmaceutical Inds
Pack of 10 Units
₹27.60
MRP ₹55.32
50.10% OFF
Storvas 10 Tablet 15
Storvas 10 Tablet 15
Ranbaxy Laboratories Ltd
Pack of 15 Units
₹68.05
MRP ₹82.99
18.00% OFF
Atorva 10 Tablet 15
Atorva 10 Tablet 15
Zydus Cadila
Pack of 15 Units
₹68.05
MRP ₹82.99
18.00% OFF
Tonact 10 Tablet 15
Tonact 10 Tablet 15
Lupin Ltd
Pack of 15 Units
₹68.02
MRP ₹82.95
18.00% OFF
Aztor 10 Tablet 15
Aztor 10 Tablet 15
Sun Pharma Laboratories Ltd.
Pack of 15 Units
₹68.05
MRP ₹82.99
18.00% OFF
Atorva 40 Tablet 10
Atorva 40 Tablet 10
Zydus Cadila
Pack of 10 Units
₹177.25
MRP ₹216.16
18.00% OFF
Lipikind 10 Tablet 15
Lipikind 10 Tablet 15
Mankind Pharmaceuticals Ltd.
Pack of 15 Units
₹37.76
MRP ₹46.05
18.00% OFF
Atorva 20 Tablet 15
Atorva 20 Tablet 15
Zydus Cadila
Pack of 15 Units
₹173.02
MRP ₹211.00
18.00% OFF

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