Alogliptin + Metformin

Dosage Forms Available

• Alogliptin + Metformin is available in tablet form for oral administration.

Age and Dose Restrictions

• This medicine is intended for use in adults only.

Contraindications

• Alogliptin + Metformin is contraindicated in individuals with known allergies to any of its ingredients.

• It is also contraindicated in patients with liver disease, severe kidney disease, individuals on dialysis treatment, metabolic acidosis or diabetic ketoacidosis and pancreatitis.

Other Medications to Avoid

• This medicine may interact with antidiabetics (e.g., insulin, glipizide, tolbutamide, glibenclamide, and rosiglitazone), corticosteroids (e.g., hydrocortisone and prednisolone), H2-receptor antagonists (e.g., cimetidine), bronchodilators (e.g., salbutamol, levosalbutamol), diuretics (e.g., furosemide), nonsteroidal anti-inflammatory drugs (NSAIDs) (e.g., ibuprofen and celecoxib), antihypertensives (e.g., enalapril, losartan), and medicines containing alcohol.

Overdose and Missed Dose

• Taking more than the prescribed dose may cause lactic acidosis, with symptoms such as muscle pain, difficulty breathing, stomach pain, dizziness, feeling cold, and weakness. If you suspect an overdose, seek medical attention immediately.

• If you miss a dose of Alogliptin + Metformin, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• To manage nausea or indigestion, consider taking this medication with food or shortly after a meal.

• If experiencing diarrhoea, it may help to drink plenty of fluids and eat fibre-rich foods.

Use in Driving and Operating Machinery

• This medicine can affect your ability to drive or operate heavy machines. Avoid these activities if you experience dizziness after taking this medicine.

Use in Pregnancy and Lactation

• This medicine is not recommended during pregnancy and breastfeeding unless specifically advised by a healthcare professional. Consult a doctor before taking this medicine during these periods.

Caution in Other Conditions

• Individuals with compromised kidney function should exercise caution when using Alogliptin + Metformin due to the risk of lactic acidosis.

• Those with liver concerns should also be cautious due to potential adverse effects on liver health.

Special Dietary and Lifestyle Recommendations

To effectively manage type 2 diabetes while using Alogliptin + Metformin:

• Follow a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Limit intake of high-sugar and high-fat foods.

• Regular physical activity can help improve blood sugar control; aim for at least 150 minutes of moderate-intensity exercise per week.

• Monitor blood sugar levels as advised by your doctor to assess the effectiveness of the treatment plan.

• Maintain a regular eating schedule to avoid sudden spikes or drops in blood sugar levels.

• Stay hydrated by drinking adequate amounts of water throughout the day which can aid in overall glucose management.