Whole Liver Extra Injection 10 ML is used as supplemental treatment for vitamin B12 deficiency and megaloblastic anaemia caused by vitamin B12 deficiency. It is a combination medicine containing Liver Fraction 1 derived from fresh liver, with vitamin B12 activity equivalent to not less than 2 mcg of cyanocobalamin per mL, and lignocaine hydrochloride 1% w/v. It belongs to the class of liver extract preparations with a local anaesthetic.
This medicine may be used when a doctor considers parenteral vitamin B12 supplementation appropriate, particularly when vitamin B12 deficiency is associated with impaired red blood cell formation. It should be administered by a healthcare professional in the dose, frequency and duration prescribed by the doctor.
A diet containing vitamin B12-rich foods such as eggs, milk, fish and meat may help support vitamin B12 intake when suitable for you. However, dietary measures should not replace prescribed treatment, particularly when vitamin B12 absorption is impaired.
Before receiving this medicine, inform your doctor about any allergies, pre-existing medical conditions and all medicines, supplements or herbal products you use. Tell your doctor if you are pregnant or breastfeeding. Follow the prescribed treatment schedule and report any persistent or serious side effects. Do not stop or change the treatment unless your doctor advises you to do so.
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FLAT 27% off on first order
Whole Liver Extra Injection 10 Ml
Pack of 10 ML
Old MRP ₹87.5
MRP ₹82.03
₹65.62
₹8.2/ML
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Whole Liver Extra Injection 10 Ml
Uses of Whole Liver Extra Injection 10 Ml
Whole Liver Extra Injection 10 ML is used to supplement vitamin B12 in cases of deficiency.
Uses of Whole Liver Extra Injection 10 ML are:
- Vitamin B12 deficiency: Used as supplemental treatment when vitamin B12 replacement by injection is considered appropriate by the doctor.
- Megaloblastic anaemia due to vitamin B12 deficiency: Helps manage anaemia caused by inadequate vitamin B12 by providing the vitamin B12 activity needed for normal red blood cell formation.
Directions for Use of Whole Liver Extra Injection 10 Ml
● Whole Liver Extra Injection 10 ML should be administered exactly as directed by your doctor.
● It should be administered only by a healthcare professional.
Route of Administration
Whole Liver Extra Injection 10 ML is administered as an intramuscular injection.
Side Effects of Whole Liver Extra Injection 10 Ml
Whole Liver Extra Injection 10 ML may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few side effects of Whole Liver Extra Injection 10 ML:
- Injection site: Injection-site pain or reaction.
- Digestive: Feeling sick (nausea) and loose motions (diarrhoea).
- Nervous system: Dizziness.
- Skin: Skin rash or itching.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, and resolve on discontinuing Whole Liver Extra Injection 10 ML. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
● Injection-site pain: Applying a cold compress may help reduce local discomfort or swelling.
● Nausea: Eating light meals and avoiding rich or spicy foods may help reduce stomach discomfort.
How Whole Liver Extra Injection 10 Ml Works?
Whole Liver Extra Injection 10 ML contains the following active components:
● Liver Fraction 2 derived from 8 g of fresh liver: It is a liver-derived preparation used as supportive therapy in liver disorders.
● Lidocaine (1%): It is a local anaesthetic that blocks nerve-signal transmission and helps reduce discomfort associated with administration.
Safety Measures & Warnings
Pregnancy
Whole Liver Extra Injection 10 ML should be used during pregnancy only if prescribed by your doctor after assessing the expected benefits and possible risks.
Breastfeeding
Inform your doctor if you are breastfeeding. Vitamin B12 is present in breast milk, and lignocaine may pass into breast milk in small amounts. Use Whole Liver Extra Injection 10 ML only as advised by your doctor.
Alcohol
No direct interaction between Whole Liver Extra Injection 10 ML and alcohol has been established. However, prolonged excessive alcohol consumption may impair vitamin B12 absorption and contribute to nutritional deficiencies.
Liver
Inform your doctor if you have liver disease. Lignocaine is metabolised mainly by the liver, and closer monitoring may be required in severe liver impairment.
Kidney
Inform your doctor if you have kidney impairment before receiving Whole Liver Extra Injection 10 ML. Clinical monitoring may be required, particularly during repeated or prolonged treatment.
Use In Driving And Operating Machinery
Whole Liver Extra Injection 10 ML may occasionally cause dizziness after administration. Avoid driving or operating machinery until you know how the medicine affects you.
Allergy
Do not use Whole Liver Extra Injection 10 ML if you are allergic to liver extract, lignocaine hydrochloride, vitamin B12, cobalt or any other component of the injection. Seek immediate medical attention if you develop breathing difficulty, facial swelling, severe itching or a widespread rash.
Children
Whole Liver Extra Injection 10 ML should be used in children only when specifically prescribed and administered under medical supervision.
Older Patients
Older adults should use Whole Liver Extra Injection 10 ML under medical supervision. Closer monitoring may be required in patients with liver, kidney or cardiovascular disorders.
Interactions of Whole Liver Extra Injection 10 Ml
Drug-Drug Interactions
Whole Liver Extra Injection 10 ML may interact with the following medicines:
● Antiarrhythmic medicines such as amiodarone or mexiletine: Concurrent use with lignocaine may increase cardiac effects and requires medical monitoring.
● Beta-blockers such as propranolol and gastric acid-reducing medicines such as cimetidine: These medicines may reduce lignocaine clearance and increase the risk of lignocaine-related adverse effects.
● Antiepileptic medicines such as phenytoin: These medicines may alter lignocaine metabolism, while concurrent use may increase cardiac depressant effects.
● Other local anaesthetics: Concurrent use may produce additive effects on the heart and nervous system.
● Chloramphenicol: This antibiotic may reduce the haematological response to vitamin B12 treatment in some patients.
Drug-Disease Interactions
Whole Liver Extra Injection 10 ML may interact with diseases or conditions, including:
● Heart rhythm or conduction disorders: Lignocaine-containing preparations should be used cautiously because they may affect cardiac conduction.
● Severe liver impairment: Reduced lignocaine metabolism may increase the risk of adverse effects.
● Severe kidney impairment: Lignocaine metabolites may accumulate during repeated administration.
● Leber’s disease: Vitamin B12 preparations should be avoided in patients with early Leber’s disease because optic nerve damage may worsen.
● Severe megaloblastic anaemia: Potassium levels and blood counts may require monitoring during the initial treatment of severe vitamin B12 deficiency.
Dosage of Whole Liver Extra Injection 10 Ml
Daily Dose
The dose and frequency of Whole Liver Extra Injection 10 ML should be determined by your doctor based on the confirmed deficiency, clinical condition and treatment response. Do not alter the prescribed dose or schedule without consulting your doctor.
Over Dose
As Whole Liver Extra Injection 10 ML is administered by a healthcare professional, an overdose is unlikely. Excessive lignocaine exposure may cause dizziness, numbness around the mouth, ringing in the ears, tremors, seizures, low blood pressure or an abnormal heartbeat. Immediate medical monitoring is required if an overdose is suspected.
Missed Dose
If you miss a scheduled dose of Whole Liver Extra Injection 10 ML, contact your doctor or healthcare provider to reschedule the injection. Do not receive an additional dose without medical advice.
Storage
- Store Whole Liver Extra Injection 10 ML according to the conditions stated on the product pack or approved package insert.
- Keep it in its original packaging and protect it from light and excessive heat.
- Do not use the injection after its expiry date.
- Keep out of reach of children.
Special Dietary And Lifestyle Recommendation
● Include vitamin B12-rich foods such as eggs, fish, meat, milk and fortified cereals in your diet, if suitable for you.
● Avoid excessive alcohol consumption because it may contribute to nutritional deficiencies.
● Maintain a balanced diet to support normal blood and nerve health.
● Attend follow-up appointments and undergo blood tests as advised by your doctor.
Fact Box
| Dosage Forms Available | Injection |
| Habit Forming | No |
| Ailment | Vitamin B12 deficiency and megaloblastic anaemia caused by vitamin B12 deficiency |
| Drug Category | Liver extract preparation with a local anaesthetic
|
| Therapeutic Category | Nutritional supplement |
Frequently Asked Questions (FAQs)
What is Whole Liver Extra Injection 10 ML used for?
How does Whole Liver Extra Injection 10 ML work?
Can Whole Liver Extra Injection 10 ML cause dizziness?
Can alcohol be consumed during treatment with Whole Liver Extra Injection 10 ML?
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Manufacturer details
Country of origin: INDIA
References
- National Library of Medicine. Cyanocobalamin Injection, USP: Prescribing Information. DailyMed. Retrieved from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2117af8a-723f-4e2f-98a6-83ad2c423751
- Electronic Medicines Compendium. Lidocaine Hydrochloride Injection BP 1% w/v: Summary of Product Characteristics. Retrieved from https://www.medicines.org.uk/emc/product/6277/smpc
- National Health Service. Vitamin B12 or folate deficiency anaemia—Treatment. Retrieved from https://www.nhs.uk/conditions/vitamin-b12-or-folate-deficiency-anaemia/treatment/
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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