Tofoday 200/300/600 MG Tablet 30

Alkem Laboratories Ltd.

Pack of 30 Units

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MRP ~~₹4330.67~~

₹3464.54

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Composition

Efavirenz (600 Mg) + Emtricitabine (200 Mg) + Tenofovir Disoproxil Fumarate (300 Mg)

Tofoday 200/300/600 MG Tablet 30 is used to manage HIV-1 infection in adults and children weighing at least 40 kg. It is a combination medicine that belongs to a class of medications known as antiretroviral medicines.

This medicine works by suppressing the HIV viral load in the body, boosting CD4 cell counts, and reducing the risk of HIV-related complications. It helps prevent the virus from multiplying in your body, which allows your immune system to work better and reduces the chance of developing AIDS-related illnesses.

This medicine should be taken as directed by your doctor. Before starting this medicine, inform your doctor about any pre-existing conditions you may have, especially liver or kidney problems, or if you are taking any other medicines. If you notice any side effects while taking this medicine, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor for optimal results.

Tofoday 200/300/600 MG Tablet 30 is used for the following:

Treatment of HIV-1 infection in adults
Management of HIV in patients weighing at least 40 kg
Suppression of HIV viral load
Prevention of HIV-related complications
Reduction of HIV transmission risk
Prevention of HIV medication resistance
Long-term management of HIV infection
Combination therapy with other antiretroviral medicines

Swallow the tablet whole with a full glass of water.
Do not crush or chew the tablet.
Take it at the same time each day.
Take this medicine on an empty stomach.

Tofoday 200/300/600 MG Tablet 30 is taken orally.

Tofoday 200/300/600 MG Tablet 30 may have the following common side effects:

Dizziness
Abnormal dreams
Insomnia
Nausea
Fatigue
Immune reconstitution syndrome: Your immune system begins to recover, but then responds to previously hidden infections with inflammatory reactions

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Tofoday 200/300/600 MG Tablet 30. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Dizziness: Taking Tofoday 200/300/600 MG Tablet 30 at bedtime can help reduce the impact of dizziness on your daily activities.
Nausea: Taking this medicine on an empty stomach may help reduce nausea.

Tofoday 200/300/600 MG Tablet 30 contains three active ingredients that work together to fight HIV-1 infection:

Efavirenz (600 mg): This component is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that binds directly to HIV reverse transcriptase, an essential enzyme the virus needs to multiply, altering its structure and blocking its ability to make copies of viral DNA.
Emtricitabine (200 mg): As a nucleoside analogue reverse transcriptase inhibitor (NRTI), this ingredient gets incorporated into the growing viral DNA chain, causing chain termination and preventing the virus from making complete copies of itself.
Tenofovir Disoproxil Fumarate (300 mg): This component is also an NRTI that works by blocking the activity of reverse transcriptase and competing with natural building blocks needed for viral DNA production, effectively preventing HIV from replicating.

Pregnancy

Tofoday 200/300/600 MG Tablet 30 is contraindicated during pregnancy, especially in the first trimester. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Tofoday 200/300/600 MG Tablet 30 is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and discuss alternative feeding options.

Alcohol

Alcohol may worsen certain side effects, such as dizziness and drowsiness. It is best to avoid alcohol during your treatment with this medicine.

Liver

Caution is advised while taking Tofoday 200/300/600 MG Tablet 30 if you have liver problems. This medicine may affect liver function, especially if you have pre-existing liver disease or hepatitis. Regular liver function tests may be needed during treatment.

Kidney

Caution is advised before using Tofoday 200/300/600 MG Tablet 30 if you have a history of kidney problems. Your doctor may monitor your kidney function regularly.

Using Machines & Driving

Tofoday 200/300/600 MG Tablet 30 may cause dizziness, drowsiness, and impaired concentration, particularly during the first few weeks of treatment. Avoid driving, operating machinery, or performing tasks that require alertness until you know how this medicine affects you.

Allergy

If you have a history of allergic reactions to any of the components in Tofoday 200/300/600 MG Tablet 30 (efavirenz, emtricitabine, or tenofovir disoproxil fumarate), do not take this medicine. Inform your doctor about any previous allergic reactions to medicines.

Children

Tofoday 200/300/600 MG Tablet 30 is contraindicated for children weighing less than 40 kg. For children who weigh at least 40 kg, this medicine should be taken under strict medical supervision. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Tofoday 200/300/600 MG Tablet 30 under medical supervision, as they may be more susceptible to side effects. Your doctor will guide you based on your overall health status.

Drug-Drug Interactions

Tofoday 200/300/600 MG Tablet 30 interacts with the following medicines:

Antifungal Medicines: Medications like voriconazole should not be taken with Tofoday 200/300/600 MG Tablet 30 as they can lead to dangerous interactions with efavirenz.
CYP3A4 Inhibitors: Medicines like ketoconazole and clarithromycin may increase efavirenz levels, potentially worsening side effects.
Nephrotoxic Medicines: Medications like cidofovir and acyclovir may increase the risk of kidney problems when taken with tenofovir disoproxil fumarate.
Ergot Derivatives: Medicines like ergotamine or dihydroergotamine are contraindicated, as efavirenz can cause dangerous interactions with these medicines.

Drug-Food Interactions

Tofoday 200/300/600 MG Tablet 30 interacts with the following:

High-Fat Meals: Taking Tofoday 200/300/600 MG Tablet 30 with fatty foods can increase the amount of efavirenz in your bloodstream, which may worsen side effects.

Drug-Disease Interactions

Tofoday 200/300/600 MG Tablet 30 interacts with the following diseases:

Liver Disease: Patients with existing liver problems, including hepatitis B or C, may experience worsening of liver function.
Kidney Disease: The tenofovir component may cause further kidney damage in patients with pre-existing kidney problems.
Psychiatric Disorders: People with a history of mental health issues may experience worsening of symptoms, including depression and suicidal thoughts.
Bone Disorders: Tenofovir disoproxil fumarate may decrease bone mineral density in patients with existing bone problems.

Daily Dose

The daily dose of Tofoday 200/300/600 MG Tablet 30 should be taken as prescribed by your doctor. The dosage may change based on individual factors such as your condition's severity and response to treatment. Always follow the prescribed dosage and never exceed it without consulting your doctor.

Over Dose

An overdose of Tofoday 200/300/600 MG Tablet 30 may cause increased dizziness, severe headache, confusion, abnormal dreams, and nausea. You might experience heightened nervous system symptoms, gastrointestinal distress, and unusual tiredness. Contact your doctor if you suspect an overdose.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next dose, skip the missed one and resume your regular schedule. Take this medicine at the same time daily, preferably at bedtime.

Store at room temperature not exceeding 30°C.
Store only in its original container. Keep the container tightly closed to protect from moisture.
Keep all medicines out of reach of children.
Do not use this medicine after the expiry date printed on the package.

Maintain a balanced diet rich in protein and nutrients to support your immune system, which is important when managing HIV infection.
Stay well-hydrated throughout the day, as this helps your body process medicines more effectively and may help reduce some side effects of antiretroviral therapy.

Fact Box

Available Dosage Types	Tablet
Habit Forming	No
Ailment	HIV-1 infection
Drug Category	HIV reverse transcriptase inhibitor
Therapeutic Category	Antiretroviral

What is Tofoday 200/300/600 MG Tablet 30 used for?

Tofoday 200/300/600 MG Tablet 30 is used to manage HIV-1 infection. It contains three medicines that work together to suppress the virus.

How does Tofoday 200/300/600 MG Tablet 30 work?

The three active ingredients in Tofoday 200/300/600 MG Tablet 30 block HIV reverse transcriptase (an enzyme the virus needs to multiply), preventing the virus from making copies of itself.

When should I take Tofoday 200/300/600 MG Tablet 30?

Take Tofoday 200/300/600 MG Tablet 30 on an empty stomach, preferably at bedtime. Taking it with food, especially fatty meals, may increase side effects.

What are the common side effects of Tofoday 200/300/600 MG Tablet 30?

Common side effects include dizziness, abnormal dreams, headache, insomnia, nausea, diarrhoea, vomiting, fatigue, and skin rash. Most are mild to moderate.

Can I take other medicines with Tofoday 200/300/600 MG Tablet 30?

Some medicines may interact with Tofoday 200/300/600 MG Tablet 30. Always inform your doctor about all medicines you are taking before starting this medicine or adding new ones.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is nearly time for your next dose, skip the missed dose and continue your regular schedule.

Will Tofoday 200/300/600 MG Tablet 30 cure my HIV infection?

No, Tofoday 200/300/600 MG Tablet 30 does not cure HIV infection. It helps control the virus but does not remove it completely from your body. You will need to continue taking it as prescribed to keep the virus suppressed.

Last Updated On 14 May. 2025 | 2:37PM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Medical Content Writer | 9 years

BAMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Alkem House, Senapati Bapat Marg, Lower Parel, Mumbai Maharashtra- 400013

Country of origin: INDIA

Expiry on or after: October 2025

In case of any issues, contact us:

support@truemeds.in|08069808861

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

MedlinePlus. (2022). Efavirenz. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a699004.html
MedlinePlus. (2022). Emtricitabine and Tenofovir. U.S. National Library of Medicine. https://medlineplus.gov/druginfo/meds/a612036.html
U.S. Food and Drug Administration. (2016). Emtriva (emtricitabine). https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/091471orig1s000lbl.pdf
DrugBank. (n.d.) Efavirenz. https://go.drugbank.com/drugs/DB00625
DrugBank. (n.d.) Tenofovir. https://go.drugbank.com/drugs/DB14126

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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