Tenepla-M 500 Tablet is used to manage type 2 diabetes mellitus by lowering blood sugar levels and improving insulin action. It combines teneligliptin and metformin, which reduce glucose production and increase insulin effectiveness. This helps prevent diabetes-related complications such as nerve damage, kidney disease, vision loss, and heart problems. Regular use along with diet and exercise supports better long-term blood glucose control and metabolic health.
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Tenepla M 500 Tablet 10
Strip of 10 Units
Old MRP ₹154
MRP ₹144.38
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CompositionAbout Tenepla M 500 Tablet 10
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Uses of Tenepla M 500 Tablet 10
Tenepla-M 500 Tablet is used to manage type 2 diabetes mellitus. It helps control high blood sugar levels by improving insulin action and reducing glucose production in the liver. Regular use along with a healthy diet and exercise lowers the risk of diabetes-related complications such as nerve damage, kidney problems, and vision issues.
Directions for Use of Tenepla M 500 Tablet 10
- Take Tenepla-M 500 tablets exactly as instructed by your doctor.
- Swallow the tablet whole with water. Do not chew, crush, or break it.
- It is advisable to take the tablet with or after meals to reduce the chances of an upset stomach.
- Take it at the same time every day unless advised otherwise by your doctor.
- Remember to consult your doctor if you have any questions or concerns about using Tenepla-M 500 Tablet.
Route of Administration
Tenepla-M 500 Tablet is taken orally, which means you swallow it with water. It should not be taken in any other way.
Side Effects of Tenepla M 500 Tablet 10
Tenepla-M 500 Tablet may cause diarrhoea, nausea, vomiting, stomach upset, headache, dizziness, and weakness. Consult your doctor if symptoms continue.
Managing the Side Effects:
Here are some natural ways to manage the side effects of Tenepla-M 500 Tablet:
- Diarrhoea: Drink plenty of fluids to stay hydrated and avoid spicy or greasy foods.
- Nausea and vomiting: Try eating smaller, more frequent meals and avoiding strong smells. Also, sip on clear liquids like water or ginger ale and eat bland foods like crackers or toast.
- Upset stomach: Eat smaller portions and avoid fatty or fried foods that can be hard to digest.
- Headache: Rest in a quiet, dark room and apply a cold compress to your forehead.
How Tenepla M 500 Tablet 10 Works?
Tenepla-M 500 Tablet contains two active ingredients: metformin hydrochloride and teneligliptin. Here's how this medicine works:
- Metformin hydrochloride helps lower the amount of glucose produced by the liver and delays the absorption of glucose from the intestines.
- Teneligliptin increases the levels of incretin — a gut-derived peptide hormone that inhibits the release of glucagon.
- Glucagon is a hormone responsible for raising the blood sugar levels.
- By blocking glucagon and stimulating the pancreas to release more insulin, teneligliptin helps lower your blood sugar levels and provides better control over diabetes.
Safety Measures & Warnings
Pregnancy
Due to the lack of adequate data, it is recommended not to use Tenepla-M 500 Tablet during pregnancy unless needed. If you are pregnant or planning to become pregnant, it is important to consult your doctor before using the medicine. They will evaluate the benefits and risks for you and your baby.
Breastfeeding
Tenepla-M 500 Tablet may pass into breast milk and result in hypoglycaemia in nursing babies. If you are breastfeeding, it is advisable to consult your doctor before taking the medicine.
Alcohol
It is recommended to avoid alcohol while taking Tenepla-M 500 Tablet as it can lower your blood glucose levels and increase the risk of side effects.
Liver
If you have severe hepatic impairment, it is contraindicated to use Tenepla-M 500 Tablet. Please consult your doctor for alternative treatment options.
Kidney
For patients with kidney disease, dose adjustment may be necessary. It is important to discuss your kidney health with your doctor before starting Tenepla-M 500 Tablet.
Using Machines & Driving
Tenepla-M 500 Tablet usually does not affect your ability to drive or operate machinery. However, if you experience dizziness or drowsiness as a side effect, avoid activities that require mental alertness.
Allergy
Do not take Tenepla-M 500 Tablet if you have a known allergy to metformin hydrochloride or teneligliptin. Consult your doctor for other safer alternatives.
Children
The safety and effectiveness of Tenepla-M 500 Tablet in children have not been established. Please consult a paediatrician for appropriate treatment options.
Older Patients
Older patients may be more susceptible to certain side effects of Tenepla-M 500 Tablet. It is important to monitor their response closely and adjust the dosage if necessary.
Interactions of Tenepla M 500 Tablet 10
Drug-Drug Interactions
Tenepla-M 500 Tablet may interact with the following medications:
- Anticoagulants like warfarin and heparin
- Antiplatelet medications like aspirin and clopidogrel
- Diuretics like furosemide and hydrochlorothiazide
- Beta-blockers like atenolol and metoprolol
- Steroids like prednisone and dexamethasone
Drug-Food Interactions
It is advisable to avoid or limit alcohol intake while taking Tenepla-M 500 Tablet as it may lead to a decrease in blood glucose levels and worsen your side effects.
Drug-Disease Interactions
Tenepla-M 500 Tablet is contraindicated in patients with the following diseases:
- Type 1 diabetes
- Diabetic ketoacidosis, with or without coma
Apart from those, individuals with the following medical conditions should also exercise caution while taking the medicine:
- Liver or kidney problems
- Heart failures
- Lactic acidosis
- Bladder cancer
- Oedema
Dosage of Tenepla M 500 Tablet 10
Daily Dose
Take Tenepla-M 500 tablets as prescribed by your doctor. The right dosage may vary depending on your condition and how your body responds to the treatment. Follow your doctor's instructions carefully.
Over Dose
An overdose of Tenepla-M 500 Tablet may lead to common side effects such as diarrhoea, nausea, vomiting, upset stomach, and headache. If you or someone else accidentally takes an overdose, seek immediate medical attention.
Missed Dose
If you forget to take a dose of Tenepla-M 500 Tablet, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Never double the dose to make up for a missed one without consulting your doctor.
Storage
- Store Tenepla-M 500 Tablet below 30°C in a tightly closed container.
- Protect the medicine from light and moisture to maintain its effectiveness.
- Keep it out of reach and sight of children to prevent accidental ingestion.
- Use the product before the expiry date mentioned on the packaging.
Diet & Lifestyle
- Follow a healthy and balanced diet rich in fruits, vegetables, whole grains, and lean proteins.
- Limit the intake of sugary foods and beverages to help control blood sugar levels.
- Engage in regular physical activity such as brisk walking or cycling to improve insulin sensitivity.
- Maintain a healthy weight as it can positively impact diabetes management.
- Monitor blood sugar levels regularly as advised by your doctor.
- If you have any concerns or questions about your diet or lifestyle, consult your doctor for personalised guidance.
Quick Tips
- Take Tenepla-M 500 Tablet with meals to avoid an upset stomach.
- Follow a healthy diet and exercise regularly while using this medicine.
- Keep track of your blood sugar levels regularly.
- Inform your doctor about any other medications you are taking.
- Avoid alcohol consumption while using Tenepla-M 500 Tablet.
Fact Box
| Available Dosage Types | Tablets |
| Habit Forming | Not addictive |
| Ailment | Type 2 diabetes mellitus |
| Drug Category | Antidiabetic medication |
| Therapeutic Category | Type 2 diabetes management |
Frequently Asked Questions (FAQs)
What is Tenepla-M 500 Tablet used for?
Tenepla-M 500 Tablet is a combination medicine used to manage type 2 diabetes mellitus. It helps control high blood sugar levels and reduces the risk of complications such as kidney damage, blindness, heart attack, and stroke.
How does Tenepla-M 500 Tablet work?
Tenepla-M 500 Tablet works by lowering glucose production in the liver, delaying glucose absorption from the intestines, increasing the body's sensitivity to insulin, and increasing insulin release from the pancreas. This helps in better control of blood sugar levels.
Can Tenepla-M 500 Tablet be taken alone or with other medications?
Tenepla-M 500 Tablets can be prescribed alone or in combination with other diabetes medications. The dosage will depend on your condition, blood sugar levels, and other medications being taken.
Is it necessary to take Tenepla-M 500 Tablet with food?
Yes, it is recommended to take Tenepla-M 500 Tablet with meals as it can help reduce the chances of developing an upset stomach.
What are the common side effects of Tenepla-M 500 Tablet?
The common side effects of Tenepla-M 500 Tablet include diarrhoea, nausea, vomiting, upset stomach, and headache.
Can Tenepla-M 500 Tablet cause low blood sugar levels?
Hypoglycaemia (low blood sugar level) is a possible side effect of Tenepla-M 500 Tablet, especially when taken with other diabetes medications like insulin. It is important to monitor your blood sugar levels regularly and consult your doctor if you experience symptoms of low blood sugar.
Are there any precautions to keep in mind before taking Tenepla-M 500 Tablet?
Before taking Tenepla-M 500 Tablet, inform your doctor if you have a history of kidney, liver, or heart disease, pancreas problems, or excessive alcohol consumption. Pregnant or breastfeeding women should consult their doctor before taking this medicine.
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Manufacturer details
Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: June 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
- D M Pharma - Teneligliptin Tablets | anti-diabetic drugs. (n.d.-b). https://www.dmpharma.co.in/Teneligliptin%20Tablets.html#:~:text=Teneligliptin%20is%20a%20third%20generation,and%20decreases%20blood%20glucose%20levels.
- Glumetza TM, 500 mg (metformin hydrochloride extended release tablets) tablet, film coated, extended release. (n.d.). FDA.gov. Retrieved August 25, 2023, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf
- Metformin: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00331
- Metformin hydrochloride. (n.d.). MedlinePlus Drug Information. Retrieved April 8, 2019, from https://medlineplus.gov/druginfo/meds/a696005.html
- Torrent Pharmaceutical Ltd. (2021). Teneligliptin. Retrieved October 27, 2022, from https://www.torrentian.com/pisheet/Upload/PI_Sheet/2991.pdf
- Goak, I. S., Lee, J. A., Jeong, M. H., Moon, S. J., & Kim, M. G. (2022). Pharmacokinetics of a Fixed-Dose Combination of Teneligliptin Hydrochloride Hydrate and Modified-Release Metformin Under Fasting and Fed Conditions in Healthy Subjects. Drug Design, Development and Therapy, 4439-4448.
- Nakamaru, Y., Hayashi, Y., Davies, M., Heuer, H. J., Hisanaga, N., & Akimoto, K. (2015). Investigation of potential pharmacokinetic interactions between teneligliptin and metformin in steady-state conditions in healthy adults. Clinical therapeutics, 37(9), 2007-2018.
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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Intellihealth Solutions Private Limited
Unit-301 & 304, Lightbridge Tunga Village, Saki Vihar Rd, Chandivali, Powai, Mumbai, Maharashtra, India, 400072.
CIN: U62099MH2019PTC320566
Telephone:09240250346
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