Sulfazee 1000 Tablet 15

Prevego Healthcare & Research Pvt.ltd.

Strip of 15 Units

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MRP ~~₹291.5~~

₹233.2

₹19.43/Units

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*MRP inclusive of all taxes

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Prescription required for this medicine

Store Below 30° C

Composition

Sulfasalazine (1000 Mg)

Strength:

500 MG 1000 MG

SULFAZEE 1000 TABLET 15 is used in adults for the treatment and long-term management of inflammatory conditions such as ulcerative colitis, Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and juvenile idiopathic arthritis. It belongs to the class of medicines known as anti-inflammatory and disease-modifying agents.

It is also prescribed for the prevention of relapses in ulcerative colitis, helping patients maintain remission between flare-ups. This medicine is not suitable for the immediate relief of acute symptoms and must be taken regularly as directed by your doctor.

Before starting SULFAZEE 1000 TABLET 15, it is important to consult your doctor. The dosage and treatment duration will depend on your condition, age, weight, liver and kidney function, and treatment response. Any unusual or severe side effects should be promptly reported.

SULFAZEE 1000 TABLET 15 is used for:

Treatment of mild to moderate ulcerative colitis.
Adjunctive therapy in severe ulcerative colitis.
Maintenance of remission in ulcerative colitis.
Management of Crohn’s disease.
Relief of symptoms in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis.
Treatment of juvenile idiopathic arthritis (in selected cases).

Swallow the tablets whole with water, preferably after meals to reduce stomach irritation.
Do not crush or chew the tablets.
Drink sufficient fluids throughout the day while taking this medicine.
Follow your doctor’s prescription carefully and do not alter the dose on your own.

SULFAZEE 1000 TABLET 15 is for oral use only.

SULFAZEE 1000 TABLET 15 may cause the following common side effects:

Headache
Indigestion
Nausea and vomiting
Changes in taste
Abdominal discomfort
Skin rash

Management Of Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of SULFAZEE 1000 TABLET 15. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Headache: Rest in a quiet environment and stay well hydrated.
Nausea/indigestion: Take the medicine after meals and avoid spicy, fatty foods.

SULFAZEE 1000 TABLET 15 contains the following active component:

Sulfasalazine (1000 mg): It reduces inflammation by inhibiting the production of prostaglandins, chemicals responsible for pain and swelling. Its breakdown products, sulphapyridine and 5-aminosalicylic acid, provide both antibacterial and anti-inflammatory effects in the intestines and joints.

Pregnancy

SULFAZEE 1000 TABLET 15 should only be used during pregnancy if clearly advised by your doctor. High doses may reduce folate absorption, which is important for foetal development. Supplementation may be required.

Breastfeeding

Sulfasalazine passes into breast milk. Use during breastfeeding is not generally recommended, as it may cause diarrhoea or blood-related issues in the infant. Consult your doctor before use.

Alcohol

Alcohol can irritate the stomach and worsen gastrointestinal side effects such as nausea or indigestion caused by SULFAZEE 1000 TABLET 15. Limiting or avoiding alcohol is advisable during treatment.

Liver

Patients with liver disease must exercise caution, as SULFAZEE 1000 TABLET 15 can increase liver enzyme levels. Regular monitoring of liver function tests is necessary.

Kidney

As SULFAZEE 1000 TABLET 15 may affect kidney function and increase the risk of kidney stones, it should be used with caution in patients with kidney disease. Adequate hydration is strongly advised.

Use In Driving And Operating Machinery

SULFAZEE 1000 TABLET 15 generally does not impair alertness. However, if you feel dizzy or unwell, avoid driving, cycling, or operating heavy machinery.

Allergy

Do not take SULFAZEE 1000 TABLET 15 if you are allergic to sulfasalazine, sulphonamides, salicylates, or any component of the tablet. Severe allergic reactions such as rash, swelling, or breathing difficulty require immediate medical attention.

Children

SULFAZEE 1000 TABLET 15 can be use in children above 6 years of age when prescribed.

Older Patients

Older patients may be more prone to blood disorders, kidney impairment, or liver issues while on SULFAZEE 1000 TABLET 15. Closer monitoring is required in this age group.

Drug-Drug Interactions

SULFAZEE 1000 TABLET 15 interacts with the following medicines:

Blood thinners (warfarin): The concomitant use may increase the risk of bleeding.
Digoxin (heart medicine): The concomitant use may reduce absorption and effectiveness.
Iron and folic acid supplements: The concomitant use may reduce absorption; supplementation may be required.
Antidiabetic medicines (glimepiride, glyburide, glipizide): The concomitant use may enhance hypoglycaemic effect.
Methotrexate (arthritis/cancer treatment): The concomitant use may increase risk of toxicity.
Azathioprine and mercaptopurine (immune-suppressing agents): The concomitant use may increase risk of bone marrow suppression.
Isoniazid (anti-tuberculosis medicine): The concomitant use may increase risk of liver damage.
Methenamine (antibiotic): The concomitant use may reduce effectiveness of this medicine.

Drug-Disease Interactions

SULFAZEE 1000 TABLET 15 should be used with caution in patients with:

Intestinal or urinary obstruction: SULFAZEE 1000 TABLET 15 may worsen blockages, leading to increased abdominal pain, swelling, or difficulty in urination.
Porphyria: SULFAZEE 1000 TABLET 15 can trigger or aggravate an acute porphyria attack due to its sulphonamide component.
Blood disorders: SULFAZEE 1000 TABLET 15 may reduce blood cell counts, increasing the risk of anaemia, infections, or unusual bleeding.

Daily Dose

The recommended dose of SULFAZEE 1000 TABLET 15 varies depending on the condition being treated and your individual response. Your doctor will decide the appropriate dosage for you.

Over Dose

An overdose may cause headache, dizziness, stomach upset, nausea, or vomiting. In severe cases, yellowing of the skin, blood disorders, or kidney problems may occur. If overdose is suspected, seek medical attention immediately.

Missed Dose

If you forget to take a dose, take it as soon as you remember. If it is nearly time for your next scheduled dose, skip the missed dose. Do not double the dose to make up for the forgotten one.

Store at room temperature in a dry place.
Keep the tablets in their original blister pack to protect from moisture.
Keep out of reach and sight of children.
Do not use after the expiry date printed on the packaging.

Drink plenty of water: To reduce the risk of kidney stones.
Low-fibre diet: Choose white rice, bread, pasta, eggs, fish, and tofu during flare-ups.
Exercise regularly: To reduce inflammation and maintain joint flexibility.

Fact Box

Dosage Forms Available	Tablet
Habit Forming	No
Ailment	Ulcerative colitis, Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, juvenile idiopathic arthritis
Drug Category	Anti-inflammatory and disease-modifying agent
Therapeutic Category	Gastrointestinal and rheumatology medicine

What is SULFAZEE 1000 TABLET 15 used for?

SULFAZEE 1000 TABLET 15 is used for the treatment of ulcerative colitis, Crohn’s disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and juvenile idiopathic arthritis.

Does SULFAZEE 1000 TABLET 15 cure ulcerative colitis?

No, it does not cure ulcerative colitis but helps to control symptoms and maintain remission.

Can I take SULFAZEE 1000 TABLET 15 during pregnancy?

It should only be used in pregnancy if clearly advised by a doctor. Folic acid supplementation may be needed.

Can I take SULFAZEE 1000 TABLET 15 while breastfeeding?

Breastfeeding is not recommended unless clearly advised by a doctor, as it may affect the baby.

Does SULFAZEE 1000 TABLET 15 affect driving?

Generally no, but avoid driving if you experience dizziness or weakness.

How long do I need to take SULFAZEE 1000 TABLET 15?

Treatment duration depends on your condition. Some patients may require long-term therapy. Always follow your doctor’s instructions.

Last Updated On 05 Jan. 2026 | 5:13AM (IST)

Certified Content

Written by

Dr. Divya Mandial

Medical Content Writer | 10 years

PhD in Chemistry

Reviewed by

Pragati Bhosale

Medical Content Reviewer | 5 years

M. Pharmacy

Check out Editorial Policy

Manufacturer details

4-6, Bora Bazar St, Borabazar Precinct, Ballard Estate, Fort, Mumbai, Maharashtra 400001

Country of origin: INDIA

Expiry on or after: December 2026

In case of any issues, contact us:

support@truemeds.in|09240250346

Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071

References

Azulfidine® sulfasalazine tablets. (N.d.). Fda.Gov. Retrieved September 17, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/007073s124lbl.pdf
Sulfasalazine. (n.d.). Medline Plus. Retrieved August 12, 2023, from https://medlineplus.gov/druginfo/meds/a682204.html
Highlights Of Prescribing Information For Sulfasalazine. (n.d.). U.S. Food And Drug Administration. Retrieved August 12, 2023, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/007073s124lbl.pdf
Sulfasalazine. (n.d.). Drugs.Com. Retrieved September 17, 2025, from https://www.drugs.com/sulfasalazine.html

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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