Sevelamer-800 Tablet is used to manage high phosphate levels in the blood in patients with chronic kidney disease, especially those on dialysis. It binds dietary phosphate in the digestive tract, preventing absorption and helping protect bones and blood vessels from damage.
This tablet should be taken with meals as prescribed by your doctor. Inform your doctor about existing medical conditions or medications. Regular use between dialysis sessions helps maintain safe phosphate levels and reduces long-term complications.
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Sevelamer 800 Tablet 10
Strip of 10 Units
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MRP ₹384
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CompositionAbout Sevelamer 800 Tablet 10
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Uses of Sevelamer 800 Tablet 10
Sevelamer-800 Tablet is used to manage high blood phosphate levels in patients with chronic kidney disease who are on dialysis. By binding excess phosphate in the digestive tract, it helps prevent complications such as bone disease and vascular calcification, supporting better long-term bone and cardiovascular health.
Directions for Use of Sevelamer 800 Tablet 10
Follow these steps while taking Sevelamer-800 Tablet:
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
If you have trouble swallowing the tablet, consult your doctor about switching to another form of this medicine.
Route of Administration
Sevelamer-800 Tablet is taken orally.
Side Effects of Sevelamer 800 Tablet 10
Sevelamer-800 Tablet may cause side effects including abdominal pain, constipation, diarrhoea, nausea, and vomiting. Long-term use may also lead to folic acid deficiency, which can cause symptoms such as fatigue or anaemia. If any of these side effects persist or worsen, consult your healthcare provider.
Managing the Side Effects:
Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Sevelamer-800 Tablet. However, if you experience any serious side effects or worsening of any symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:
Abdominal pain: Consider taking this medicine with food if it causes you stomach discomfort.
Nausea: If you feel nauseous, try taking Sevelamer-800 Tablet after your meals to lessen this effect.
How Sevelamer 800 Tablet 10 Works?
Sevelamer-800 Tablet contains sevelamer (800 mg). Here is how it works in the body:
Binds to Phosphate: Sevelamer has multiple amine groups that bind to phosphate molecules in the gut through ionic interactions. This binding action is central to how the medicine manages high phosphate levels.
Prevents Absorption: The phosphate-sevelamer complex that forms is insoluble, preventing the absorption of phosphate into the bloodstream. This reduces the concentration of free phosphate in the blood.
Eliminates Through Faeces: The phosphate that is bound to sevelamer is not absorbed but is instead excreted in the faeces.
Non-absorbable: Sevelamer itself does not get absorbed into the blood. This means it carries out its function in the digestive tract without entering the bloodstream.
Safety Measures & Warnings
Pregnancy
Sevelamer-800 Tablet isn't absorbed by the body after oral consumption, hence, it is not likely to affect an unborn baby. However, it's always good to consult your doctor before taking this medicine during pregnancy.
Breastfeeding
Since Sevelamer-800 Tablet doesn't get absorbed systemically, it's not expected to pass into breast milk. However, if you are breastfeeding, always consult your doctor before using this medicine.
Alcohol
The effects of consuming alcohol while taking Sevelamer-800 Tablet have not been studied. It would be wise to discuss this with your doctor.
Liver
Sevelamer-800 Tablet is generally safe for patients with liver issues. However, discuss any liver-related concerns with your doctor before beginning this medication.
Kidney
Sevelamer-800 Tablet is used to manage high blood phosphate levels in patients with chronic kidney disease on dialysis. It's important to consult your doctor if you have any kidney problems before starting this medication.
Using Machines & Driving
As far as we know, there are no restrictions on driving or operating machinery while taking Sevelamer-800 Tablet. If you experience any side effects that could affect these activities, please consult your doctor.
Allergy
If you're allergic to sevelamer carbonate or any other components of Sevelamer-800 Tablet, avoid using this medicine. Consult your doctor for alternatives.
Children
The safety and effectiveness of Sevelamer-800 Tablet in children haven't been established. Therefore, caution should be exercised when considering its use in children under 18 years of age. Always consult a doctor first.
Older Patients
Older patients can use Sevelamer-800 Tablet under medical supervision. They may be more susceptible to its side effects. Seek advice from your doctor if you are over 70 years of age before starting this medicine.
Interactions of Sevelamer 800 Tablet 10
Drug-Drug Interactions
Sevelamer-800 Tablet interacts with the following medicines:
Antibiotics: Sevelamer-800 Tablet can interact with ciprofloxacin, reducing its absorption. It's recommended to take ciprofloxacin at least one hour before Sevelamer-800 Tablet.
Immune System Medications: The absorption of medications like mycophenolate and tacrolimus may be reduced when taken with Sevelamer-800 Tablet. It's best to take these medicines either one hour before or three hours after taking Sevelamer-800 Tablet.
Thyroid Medications: Sevelamer-800 Tablet can interfere with the absorption of levothyroxine, an important medication for underactive thyroid. To avoid this interaction, levothyroxine should be taken four hours before or after Sevelamer-800 Tablet.
Drug-Disease Interactions
Sevelamer-800 Tablet interacts with the following diseases:
Gastrointestinal Disorders: Patients with bowel obstruction, swallowing disorders, severe gastrointestinal motility problems, or major GI tract surgery should take caution while using Sevelamer-800 Tablet due to the risk of bowel obstruction or perforation.
Dosage of Sevelamer 800 Tablet 10
Daily Dose
Your doctor will prescribe the daily dose of Sevelamer-800 Tablet. This may vary depending on factors like your condition and how you respond to the medicine. Always stick to the prescribed dosage and consult your doctor before making any changes.
Over Dose
If you accidentally take more than your prescribed dose, you may experience symptoms like severe constipation. If you feel unwell after an overdose, it's important to let your doctor know.
Missed Dose
If you've missed a dose of Sevelamer-800 Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and carry on with your regular schedule. Never alter your dosage without talking to your doctor first.
Storage
Store Sevelamer-800 Tablet at room temperature, ideally between 20°C to 25°C.
Keep the container tightly closed to protect from moisture.
Always keep this medicine out of sight and reach of children.
Remember, it's important to use the medicine before its expiry date.
Diet & Lifestyle
Limit your intake of foods that are high in phosphate. These include dairy products, nuts, beans, and whole grains. This can help manage your phosphate levels along with taking Sevelamer-800 Tablet.
Stay hydrated but avoid fizzy drinks as they are often high in phosphates. Opt for plain water or herbal tea instead. This can aid in maintaining a healthy balance of electrolytes in your body.
Fact Box
| Available Dosage Types | Tablet |
| Habit Forming | No |
| Ailment | Chronic Kidney Disease, Hyperphosphatemia |
| Drug Category | Phosphate Binder |
| Therapeutic Category | Electrolyte Regulator |
Frequently Asked Questions (FAQs)
What is the purpose of taking Sevelamer-800 Tablet?
It helps to manage high levels of phosphate in the blood for people with chronic kidney disease who are on dialysis.
How does Sevelamer-800 Tablet work?
It works by binding to phosphate from food in your stomach, preventing its absorption into your bloodstream, thereby lowering your phosphate levels.
Can I chew or crush Sevelamer-800 Tablet if I have trouble swallowing it?
No, tablets must be swallowed whole. If swallowing is difficult, consult your doctor for an alternative option like a sevelamer oral suspension.
Is there any specific time to take Sevelamer-800 Tablet?
You must take the medicine as directed by your doctor.
Are there any side effects of Sevelamer-800 Tablet?
Yes, it may cause abdominal pain, constipation, diarrhoea, nausea and vomiting. Consult your doctor if these symptoms persist or worsen.
Can I take other oral medicines while using Sevelamer-800 Tablet?
Be sure to administer other oral medicines at least one hour before or three hours after taking Sevelamer-800 Tablet to avoid interference with absorption.
What should I do if I miss a dose of Sevelamer-800 Tablet?
If you miss a dose, take it as soon as you can with food. However, if it's nearly time for the next dose, skip the missed one and continue as normal.
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Manufacturer details
E-673, DSIDC, NARELA INDUSTRIAL AREA NEW DELHI - 110040 Delhi - India
Country of origin: INDIA
Country of origin: INDIA
Expiry on or after: July 2026
In case of any issues, contact us:
support@truemeds.in|09240250346
Address: 6th floor, Urmi Corporate Park Solaris, Saki Vihar Road, Andheri East, Mumbai 400071
References
DailyMed. (n.d.). Sevelamer- Label - SEVELAMER CARBONATE- sevelamer carbonate tablet. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9977f652-b3e7-43bc-bf3f-1f54698c5f7a
U.S. Food and Drug Administration. (n.d.). Sevelamer Carbonate Tablets. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/022127Orig1s021lbl.pdf
Ketteler, M., Rix, M., Fan, S., Pritchard, N., Oestergaard, O., Chasan-Taber, S., Heaton, J., Duggal, A., & Kalra, P. A. (2008). Efficacy and tolerability of sevelamer carbonate in hyperphosphatemic patients who have chronic kidney disease and are not on dialysis. Clinical journal of the American Society of Nephrology : CJASN, 3(4), 1125–1130. https://doi.org/10.2215/CJN.05161107
Barna, M. M., Kapoian, T., & O'Mara, N. B. (2010). Sevelamer carbonate. The Annals of pharmacotherapy, 44(1), 127–134. https://doi.org/10.1345/aph.1M291
Perry, C. M., & Plosker, G. L. (2014). Sevelamer carbonate: a review in hyperphosphataemia in adults with chronic kidney disease. Drugs, 74(7), 771–792. https://doi.org/10.1007/s40265-014-0215-7
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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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