Sevedial 400 Tablet 10 is a medicine used to control high blood phosphate levels (hyperphosphataemia) in adults with chronic kidney disease who are receiving dialysis treatment. Keeping phosphate levels controlled helps support bone health.
It contains sevelamer, a non-calcium phosphate binder. Take it with meals as prescribed, so it can bind to phosphate in food and prevent its absorption into the bloodstream. Continue taking it regularly as advised by your doctor.
Following a kidney-friendly diet low in phosphorus forms a vital part of treatment. Limit phosphorus-rich foods such as dairy products, processed meats, cola beverages, and nuts as guided by your healthcare team.
Before taking this medicine, inform your doctor if you have bowel obstruction, severe constipation, difficulty swallowing, or major digestive surgery history. Inform your doctor if you are pregnant or breastfeeding.
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Sevedial 400 Tablet 10
Strip of 10 Units
Old MRP ₹330
MRP ₹309.38
₹154.69
₹15.47/Units
100% genuine medicines
Safe & secure payments
15 days Easy returns
Prescription required for this medicine
Store Below 30° C
CompositionAbout Sevedial 400 Tablet 10
Uses of Sevedial 400 Tablet 10
Sevedial 400 Tablet 10 is used to manage elevated phosphate levels in adults with chronic kidney disease on dialysis, supporting bone and cardiovascular health.
Uses of Sevedial 400 Tablet 10 are:
- Phosphate Control: Lowers and maintains healthy blood phosphate levels in adults with chronic kidney disease on dialysis.
- Bone Health Support: Helps preserve bone strength by preventing calcium loss from bones caused by high phosphate levels.
- Cardiovascular Protection: Reduces the risk of blood vessel calcification associated with high phosphate levels.
Directions for Use of Sevedial 400 Tablet 10
Follow these instructions while taking Sevedial 400 Tablet 10:
- Swallow the tablet whole with a glass of water during meals.
- Do not crush, chew, split, or break the tablet.
- Check the expiry date of the medicine before taking it.
- Always consult your doctor before changing your dose or stopping the medicine.
Route of Administration
Sevedial 400 Tablet 10 is taken orally.
Side Effects of Sevedial 400 Tablet 10
Sevedial 400 Tablet 10 may cause some side effects that are usually mild and go away as your body adjusts to the medicine.
A few common side effects of Sevedial 400 Tablet 10:
- Digestive: Feeling sick (nausea), vomiting, indigestion, loose motions (diarrhoea), constipation, and gas.
- Abdominal: Stomach pain or mild abdominal discomfort.
If side effects do not improve or become serious, speak to your doctor right away.
Management Of Side Effects:
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sevedial 400 Tablet 10. However, if you experience any serious side effects or worsening symptoms, please consult your doctor.
Here are some tips to help manage two of these common side effects:
- Nausea: Try taking Sevedial 400 Tablet 10 with food or milk to help reduce feelings of nausea.
- Dyspepsia: If you are feeling discomfort in your stomach after taking this medicine, consider taking it after meals to lessen this effect.
How Sevedial 400 Tablet 10 Works?
Sevedial 400 Tablet 10 contains sevelamer (400 mg) that functions in the body as follows:
- Phosphate binding: Sevelamer binds dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. This action subsequently reduces blood phosphate levels.
- Cholesterol reduction: Apart from controlling phosphate levels, sevelamer also reduces serum LDL cholesterol and total cholesterol levels.
Safety Measures & Warnings
Pregnancy
Caution is advised while taking Sevedial 400 Tablet 10 if you are pregnant. It is best to consult your doctor before taking this medicine.
Breastfeeding
The safety of Sevedial 400 Tablet 10 in nursing mothers has not been established. It's advisable to discuss this with your doctor before using this medicine while breastfeeding.
Alcohol
There's no specific information about any interaction between Sevedial 400 Tablet 10 and alcohol. However, it's always wise to seek your doctor's advice before consuming alcohol while on medication.
Liver
Sevedial 400 Tablet 10 is primarily used in patients with kidney disease, so there isn't much data about its effects on liver health. If you have liver problems, it would be wise to discuss them with your doctor before starting this medication.
Kidney
Sevedial 400 Tablet 10 is used to manage high phosphate levels in patients with chronic kidney disease, so it is essential for patients with renal issues. However, always consult your doctor before starting any new medication.
Use In Driving And Operating Machinery
No specific information suggests that Sevedial 400 Tablet 10 would affect the ability to operate machinery or drive. However, if you feel unwell or experience side effects, choose not to engage in such activities and consult your doctor.
Allergy
If you are allergic to sevelamer or any other ingredients in Sevedial 400 Tablet 10, avoid using this medicine. Always inform your doctor about your allergies before starting a new medication.
Children
The safety and efficacy of Sevedial 400 Tablet 10 in children have not been established. Therefore, it's recommended not to give this medicine to children under 18 without consulting a doctor.
Older Patients
Older patients should take Sevedial 400 Tablet 10 under medical supervision. They may be more prone to its side effects and might have liver and kidney issues. Your doctor will guide you based on your health status.
Interactions of Sevedial 400 Tablet 10
Drug-Drug Interactions
Sevedial 400 Tablet 10 interacts with the following medicines:
- Antibiotics: Medications like ciprofloxacin may reduce absorption when taken alongside Sevedial 400 Tablet 10, potentially weakening their effects.
- Cardiac medicines: Specific medicines such as digoxin and metoprolol may interact with Sevedial 400 Tablet 10, decreasing their bioavailability and effectiveness.
- Blood pressure regulators: Medicines such as enalapril could have reduced bioavailability due to interactions with Sevedial 400 Tablet 10.
- Anticoagulants: The absorption of anticoagulants like warfarin may be affected when taken with Sevedial 400 Tablet 10, possibly altering their therapeutic effects.
Drug-Food Interactions
No specific food interactions have been reported for Sevedial 400 Tablet 10.
Drug-Disease Interactions
Sevedial 400 Tablet 10 interacts with the following diseases:
- Gastrointestinal disorders: Patients suffering from severe gastrointestinal motility issues or with a history of major gastrointestinal tract surgery should exercise caution when taking Sevedial 400 Tablet 10.
Dosage of Sevedial 400 Tablet 10
Daily Dose
The daily dose of Sevedial 400 Tablet 10 should be taken as instructed by your doctor. This dosage might vary depending on your health situation and how your body reacts to the medicine. Always follow the dosage prescribed by your doctor and never increase it without their guidance. For comprehensive information, refer to the package insert.
Over Dose
Taking too much of any medicine can be harmful. If you accidentally take an extra dose of Sevedial 400 Tablet 10, you may experience more severe versions of the common side effects such as nausea or stomach upset. If this happens, let your doctor know.
Missed Dose
If you forget to take a dose of Sevedial 400 Tablet 10, take it as soon as you recall. But if it's nearly time for your next dose, skip the missed one and continue your normal schedule. Never double up on doses without consulting your doctor.
Storage
- Store Sevedial 400 Tablet 10 in a cool, dry place. The ideal storage temperature is room temperature below 30°C.
- Protect the tablet from heat and moisture.
- Keep it out of reach and sight of children.
- Always use the tablet before its expiry date.
Special Dietary And Lifestyle Recommendation
- Monitor your dietary phosphate intake. As Sevedial 400 Tablet 10 manages high blood phosphate levels, reducing your intake of phosphate-rich foods such as dairy products, whole grains, and organ meats can assist in managing your condition.
- Maintain a heart-healthy lifestyle. Regular exercise and a diet low in saturated fats can help reduce your risk of heart disease and stroke, which are often associated with chronic kidney disease.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Chronic Kidney Disease, Hyperphosphatemia |
| Drug Category | Phosphate Binder |
| Therapeutic Category | Hyperphosphatemia Management |
Frequently Asked Questions (FAQs)
What is the purpose of Sevedial 400 Tablet 10?
This medicine is used to manage high levels of phosphate in the blood in adults with chronic kidney disease on dialysis.
How does the Sevedial 400 Tablet 10 work?
It contains sevelamer, which binds dietary phosphate in the gut, preventing its absorption and thereby reducing blood phosphate levels.
Can I crush or chew the Sevedial 400 Tablet 10?
No, these tablets should be swallowed whole. Crushing, chewing, or breaking them can affect how they work.
What are the possible side effects of Sevedial 400 Tablet 10?
Common side effects include vomiting, nausea, diarrhoea, stomach discomfort, abdominal pain, wind, and constipation. Consult your doctor if symptoms persist or worsen.
Can I take other medicines with Sevedial 400 Tablet 10?
Sevelamer may reduce the effect of certain medicines. Always consult your doctor before taking this tablet with other medicines.
How should I store the Sevedial 400 Tablet 10?
Store it at room temperature below 30°C, protect it from moisture and heat, and keep it out of children's reach.
How should I take Sevedial 400 Tablet 10?
It should be taken orally with meals or as directed by your doctor.
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Manufacturer details
Country of origin: INDIA
References
- MedlinePlus. (2022, February 23). Sevelamer Carbonate. U.S. National Library of Medicine. Retrieved April 1, 2024, from https://medlineplus.gov/druginfo/meds/a601248.html
- U.S. Food and Drug Administration. (2007). Label: Sevelamer carbonate tablet, film-coated. Retrieved April 1, 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/021179s021lbl.pdf
- Sevelamer. (n.d.). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB00658
- PubChem. (n.d.). Sevelamer. https://pubchem.ncbi.nlm.nih.gov/compound/Sevelamer
- Sevelamer carbonate 800 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). (n.d.). https://www.medicines.org.uk/emc/product/8784/smpc
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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