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CompositionGZIDE XR 60 TABLET 10is a long-acting medication used to control blood sugar levels in type 2 diabetes. It stimulates insulin release from the pancreas, helping to maintain stable blood sugar levels.
Follow your doctor’s instructions for the correct dosage. Inform your doctor about any pre-existing conditions or medications you are taking, and report side effects immediately. Continue taking the medicine for the entire prescribed duration for the best results.
GZIDE XR 60 TABLET 10 is used for the management of Type 2 diabetes mellitus. It helps regulate blood sugar levels by stimulating insulin release from the pancreas and supporting better glucose control, especially when combined with diet and exercise.
Take this medicine orally with a glass of water.
Do not chew or crush the tablet, swallow it whole.
Always take this medication as advised by your doctor.
GZIDE XR 60 TABLET 10 is taken orally.
GZIDE XR 60 TABLET 10 may cause side effects such as upper respiratory tract infection, headache, nausea, diarrhoea, dizziness, hypoglycaemia (low blood sugar), arthralgia (joint pain), and edema (swelling). If these side effects persist or worsen, consult your doctor.
Most side effects are temporary and generally harmless, which resolve on discontinuing the use of GZIDE XR 60 TABLET 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.
Here are a couple of tips to manage common side effects:
Hypoglycaemia: If you feel dizzy, try having a small snack or drink containing sugar.
Diarrhoea: Try taking GZIDE XR 60 TABLET 10 with food to reduce this effect.
GZIDE XR 60 TABLET 10 contains gliclazide (60 mg), which works on the body in several ways:
Insulin secretion: Gliclazide stimulates the release of insulin from functioning pancreatic beta cells.
Insulin sensitivity: It enhances the sensitivity of target tissues like muscle, fat, and liver to insulin. This means these tissues are better able to absorb and use glucose from the blood.
Glucose output: Gliclazide suppresses the production of glucose in the liver.
Carbohydrate absorption: It slows down the absorption of carbohydrates from your intestine after meals.
Using GZIDE XR 60 TABLET 10 when you're pregnant is not recommended. It's best to consult your doctor before taking this medicine.
If you are breastfeeding, it is not known whether gliclazide passes into breast milk. It's safer to discontinue nursing or medicine during this period.
Be cautious with alcohol intake while on this medication, as it may increase the risk of low blood sugar (hypoglycaemia).
For those with liver health issues, the use of GZIDE XR 60 TABLET 10 should be initiated conservatively at the lower end of the dosing range. Your doctor will guide you based on your health status.
If you have kidney problems, caution is advised when taking GZIDE XR 60 TABLET 10. Dosage adjustments may be necessary, as clearance can be reduced in patients with renal impairment.
GZIDE XR 60 TABLET 10 might cause dizziness or blurred vision in some individuals. Don't drive or operate machinery if you experience these symptoms.
If you have known allergies to gliclazide, other sulfonylureas, sulfonamides, or any other components of GZIDE XR 60 TABLET 10, avoid using this medicine.
The safety and effectiveness of GZIDE XR 60 TABLET 10 have not been well-established in children. Therefore, be cautious when giving it to individuals under 18 years of age. Consult your paediatrician before giving any medicine to children.
Older patients might be more susceptible to the side effects of GZIDE XR 60 TABLET 10, including low blood sugar levels (hypoglycaemia). Such patients should start at the lower end of the dosing range strictly under medical supervision.
GZIDE XR 60 TABLET 10 interacts with the following medicines:
Beta-blockers: Medications such as propranolol and metoprolol can enhance the blood sugar-lowering effect of GZIDE XR 60 TABLET 10, potentially leading to hypoglycaemia (low blood sugar levels).
ACE inhibitors: Medications like lisinopril and enalapril can increase the hypoglycaemic effect of GZIDE XR 60 TABLET 10.
Thiazides: Diuretics such as hydrochlorothiazide can diminish the blood sugar-lowering effect of GZIDE XR 60 TABLET 10.
Corticosteroids: Medications like prednisone and dexamethasone can reduce the hypoglycaemic effect of GZIDE XR 60 TABLET 10.
Antifungal medications: Medicines like miconazole can cause severe hypoglycaemia when taken with GZIDE XR 60 TABLET 10.
Cholesterol-lowering medicines: Medications like colesevelam may decrease the absorption of gliclazide when used alongside GZIDE XR 60 TABLET 10.
Certain foods may interact with GZIDE XR 60 TABLET 10. Details are as follows:
High-fibre foods: Foods high in fibre may slow down the absorption of gliclazide, potentially reducing its effectiveness.
GZIDE XR 60 TABLET 10 interacts with the following diseases:
Liver disease: This medication is metabolised in the liver; thus, patients with liver disease should use it cautiously as it could exacerbate their condition.
Renal impairment: Gliclazide is excreted through the kidneys. Therefore, in patients with kidney disease, the clearance of gliclazide may be reduced, potentially leading to hypoglycaemia.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency: GZIDE XR 60 TABLET 10 can cause hemolytic anaemia in patients with G6PD deficiency.
Your doctor will prescribe the daily dose of GZIDE XR 60 TABLET 10 depending on factors like your condition's severity and how you respond to the medicine. Make sure to adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.
If you accidentally take more GZIDE XR 60 TABLET 10 than prescribed, you may experience symptoms such as tremors, increased appetite, and sweating, which are signs of hypoglycaemia (low blood sugar). If you notice these symptoms or if they worsen, inform your doctor immediately.
If you forget to take a dose of GZIDE XR 60 TABLET 10, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.
Store your GZIDE XR 60 TABLET 10 in a tightly closed container.
Keep in a dark, dry place.
Keep it out of reach and sight of children.
Incorporate a balanced diet rich in whole grains, fruits, and vegetables into your daily routine. This can aid in controlling blood sugar levels alongside the use of GZIDE XR 60 TABLET 10.
Engage in regular physical activities, such as walking or cycling. This helps improve insulin sensitivity, which is beneficial for managing type 2 diabetes mellitus.
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Type 2 Diabetes Mellitus |
| Drug Category | Sulfonylurea Antidiabetic |
| Therapeutic Category | Oral Hypoglycemic |
GZIDE XR 60 TABLET 10 is a medicine used to manage type 2 diabetes in adults, helping to control blood sugar levels.
The active ingredient, gliclazide, stimulates insulin secretion and improves insulin sensitivity, managing blood sugar levels effectively.
No, it's not suitable for patients with type 1 diabetes, diabetic ketoacidosis, or allergies to sulfonylureas, sulfonamides, or any of the excipients.
Yes, gliclazide can cause hypoglycaemia (low blood sugar), especially in elderly or malnourished patients and those with liver or kidney problems.
Some medicines, like thiazides, may interact with gliclazide and affect its function. Always consult your doctor before starting any new medicine.
Gliclazide is not recommended during pregnancy unless prescribed by your doctor. If you're pregnant or planning to be, consult your doctor about alternatives.
Overdosing may lead to severe hypoglycaemia. Seek immediate medical help if you've taken more than the recommended dose.
Check out Editorial Policy
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 3475, Gliclazide. Retrieved August 12, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Gliclazide.
National Health Service. (2021). Gliclazide [Internet]. NHS. https://www.nhs.uk/medicines/gliclazide/
Ishibashi F, Takashina S. (1990, March) The effect of timing on gliclazide absorption and action. Hiroshima J Med Sci. 39(1):7-9. https://pubmed.ncbi.nlm.nih.gov/2373640/
Gliclazide. (2024, 5). Diabetes UK. https://www.diabetes.org.uk/guide-to-diabetes/managing-your-diabetes/treating-your-diabetes/tablets-and-medication/sulphonylureas/gliclazide
Drouin P, Standl E; Diamicron MR Study Group. (2004, November). Gliclazide modified release: results of a 2-year study in patients with type 2 diabetes. Diabetes Obes Metab. 6(6):414-21. https://pubmed.ncbi.nlm.nih.gov/15479217/
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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