Satrogyl-O Tablet is used to treat diarrhea caused by mixed infections involving both bacteria and protozoa. It contains a combination of Satranidazole, an antiprotozoal agent, and Ofloxacin, a fluoroquinolone antibiotic. These active ingredients work together to inhibit the growth and repair of the DNA of harmful microorganisms, effectively clearing the infection from the gastrointestinal tract.
This medication provides rapid relief from distressing symptoms like loose motions, abdominal cramps, and bloating. The treatment helps restore normal gut function and prevents the spread of the infection to other parts of the digestive system. It is particularly effective for managing conditions such as amoebic dysentery and complex intestinal infections.
You should complete the full course of this tablet as prescribed by your doctor to ensure the infection is completely eradicated and to prevent antibiotic resistance. Avoid the consumption of alcohol while using this medication, as it may lead to unpleasant side effects. Consult your healthcare provider if you have any pre-existing liver or kidney conditions before starting the treatment.
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Satrogyl O Tablet 10
Strip of 10 Units
Old MRP ₹217
MRP ₹203.44
₹162.75
₹20.34/Units
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CompositionAbout Satrogyl O Tablet 10
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Uses of Satrogyl O Tablet 10
Satrogyl-O Tablet is used to treat diarrhoea caused by mixed infections involving both bacteria and parasites. It helps eliminate infection-causing organisms from the digestive tract, relieving symptoms such as loose stools and abdominal pain while supporting faster recovery and improved gut health.
Directions for Use of Satrogyl O Tablet 10
- Swallow the whole tablet with a glass of water.
- Do not crush or chew the tablet, as this may affect the way the medication is absorbed in the body.
- Do not change your dose of Satrogyl-O Tablet or take them more often than prescribed.
Route of Administration
Satrogyl-O Tablet is taken orally as a tablet.
Side Effects of Satrogyl O Tablet 10
Satrogyl-O Tablet may cause side effects such as nausea, vomiting, abdominal discomfort, dry mouth, and constipation, which are generally mild but may cause gastrointestinal discomfort. If any of these symptoms persist or worsen, consult your healthcare provider.
Management Of Side Effects:
Most of the side effects are temporary and harmless, and get resolved by discontinuing the tablet. These may not require medical attention. To combat abdominal discomfort, take this tablet with food. If you experience severe or persistent side effects from this tablet, consult your doctor.
How Satrogyl O Tablet 10 Works?
Satrogyl-O Tablet contains the following components:
- Satranidazole (300 mg): It is an antibacterial and antiprotozoal medicine belonging to the nitroimidazole class. It acts against parasites such as amoebas and giardia by disrupting their DNA structure and inhibiting their growth. This helps to treat protozoal infections that can cause diarrhoea and other gastrointestinal issues.
- Ofloxacin (200 mg): It is a fluoroquinolone antibiotic that inhibits the bacterial enzyme DNA gyrase. This enzyme is essential for DNA replication and repair. By interfering with this process, ofloxacin disrupts bacterial DNA synthesis and inhibits bacterial growth. This makes it effective against a broad spectrum of bacteria.
Safety Measures & Warnings
Pregnancy
Pregnant women should cautiously take Satrogyl-O Tablet. It should only be taken if the potential benefit justifies the potential risk to the foetus. Inform your doctor while this tablet is prescribed to you during pregnancy.
Breastfeeding
Breastfeeding mothers should cautiously take Satrogyl-O Tablet. It may pass to the infant through breast milk. Before taking this tablet while breastfeeding, it is recommended to inform your doctor.
Alcohol
Alcohol is not recommended while taking Satrogyl-O Tablet. It can add to dizziness and lightheadedness due to this tablet. It can also worsen the side effects of this medication.
Liver
Satrogyl-O Tablet should be cautiously used in patients with severe liver disease, such as liver cirrhosis. If you have a severe liver problem, consult your doctor before taking this tablet.
Kidney
When taking Satrogyl-O Tablet, patients with kidney disease should exercise caution. Dose adjustments may be required in such patients. If you have kidney dysfunction, it is better to consult your doctor before taking this tablet.
Use In Driving And Operating Machinery
Satrogyl-O Tablet may affect your mental or physical abilities to operate machinery or drive. After taking the tablet, you may experience dizziness. Therefore, avoiding any attentive task is recommended after taking this medicine.
Allergy
If you are allergic to ofloxacin, satranidazole, or any other ingredient in Satrogyl-O Tablet, you should not take it. Read the label and check the ingredients in the tablet to avoid allergic reactions.
Children
Satrogyl-O Tablet is not intended for children below 18 years of age.
Older Patients
Older patients with kidney dysfunction, liver impairment, and heart problems should take this tablet cautiously. Elderly patients taking corticosteroids should also cautiously take this tablet. They may also take other medications that can interact with this tablet. Consult your doctor and discuss your prescription medications before taking this tablet.
Interactions of Satrogyl O Tablet 10
Drug-Drug Interactions
Satrogyl-O Tablet can interact with medications, including:
- Antidiabetic agents such as insulin and glibenclamide. The concomitant use can result in low blood sugar.
- Stomach acid reducers such as cimetidine. The concomitant use results in increased blood concentration of this tablet.
- Immunosuppressants such as cyclosporine and methotrexate. The concomitant use results in increased blood concentration of these medications.
- Antigout medications such as probenecid. Using probenecid together with this tablet can impact the elimination of these medicines through the kidneys.
- Bronchodilators such as theophylline. The concomitant use can increase the levels of theophylline in blood.
- Anticoagulants such as warfarin. The concomitant use can enhance the effects of warfarin.
- Antiarrhythmics such as quinidine and disopyramide. This tablet should be avoided in patients using these heart medications.
- Medicines or dietary supplements containing iron or zinc. It can affect the absorption of this tablet.
- Medicines for stomach ulcers such as sucralfate. It can affect the absorption of this tablet.
- Antacids containing magnesium or aluminium. These can affect the absorption of this tablet.
- Corticosteroids such as prednisone. The concomitant use of corticosteroids may increase the risk of swelling of the tendons with pain, and tenderness.
- Anti-inflammatory drugs (NSAIDs) such as ibuprofen or diclofenac. The concomitant use can make you more prone to fits.
Drug-Disease Interactions
Satrogyl-O Tablet can interact with diseases, including:
- History of seizures: This tablet should be cautiously used in patients with a history of seizures and epilepsy.
- Liver impairment: The excretion of this tablet may be reduced in patients with severe liver impairment.
- Kidney impairment: This tablet is excreted by the kidney. Therefore, a dose adjustment may be required in patients with kidney impairment.
- Tendonitis: This tablet may increase the risk of tendonitis and tendon rupture.
- Low blood potassium (hypokalemia): This tablet may exacerbate irregular heartbeats in patients with low blood potassium.
Dosage of Satrogyl O Tablet 10
Daily Dose
Take the recommended dose of Satrogyl-O Tablet as your doctor prescribes. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and not exceed it without consulting your doctor.
Over Dose
If you take an excessive amount of Satrogyl-O Tablet by accident, it is essential to get immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include nausea, headache, and dizziness.
Missed Dose
If you forgot to take this tablet, take it as soon as you remember. If the time for the next dosage is close, it is recommended to skip the missed one now and resume your regular dosage pattern. Never increase your dosage without consulting your doctor.
Storage
- Store this medicine at a temperature below 25 ºC in a dry place.
- Protect it from light.
- Keep Satrogyl-O Tablet away from children.
Special Dietary And Lifestyle Recommendation
- Drink clear fluids like water, oral rehydration solutions, and diluted fruit juices. You can make an oral rehydration solution by mixing salt, sugar, and water to replenish electrolytes.
- Stick to the BRAT diet – bananas, rice, applesauce, and toast. These foods are gentle on the stomach and can help firm up stools.
- Dairy products and fatty foods can worsen diarrhoea. Avoid these until your symptoms improve.
- Foods with natural probiotics, like yoghurt, can help restore the balance of beneficial gut bacteria.
- Eat smaller, more frequent meals to avoid stomach discomfort.
- Both caffeine and alcohol can contribute to dehydration, so it's best to avoid them during diarrhoea.
Fact Box
| Dosage Forms Available | Tablet |
| Habit Forming | No |
| Ailment | Diarrhoea of mixed infection |
| Drug Category | Antibacterial and Antiprotozoal |
| Therapeutic Category | Antibacterial and Antiprotozoal |
Frequently Asked Questions (FAQs)
Is Satrogyl-O Tablet used for bacterial infections?
Yes, this tablet treats bacterial infections, mainly when they are part of mixed infections involving protozoal (parasitic) components.
Is Satrogyl-O Tablet antibiotic?
This tablet contains ofloxacin, an antibiotic component, making it effective against bacterial infections.
Can Satrogyl-O Tablet be taken once or twice a day?
This tablet should be taken for the dosage and duration as prescribed by your doctor.
Does Satrogyl-O Tablet make you sleepy?
This tablet may cause drowsiness as a side effect, so it's advisable to be cautious when performing tasks that require alertness, such as driving while taking this medication.
Is Satrogyl-O Tablet safe in pregnancy?
This tablet is generally not recommended during pregnancy unless the potential benefits outweigh the risks and a doctor prescribes it. Pregnant women should consult with a doctor for guidance on safe alternatives.
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Manufacturer details
Country of origin: INDIA
References
- FLOXIN ® Tablets (Ofloxacin Tablets) Fda.Gov. (Retrieved October 2023). https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019735s059lbl.pdf
- Ofloxacin 400 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). (n.d.). Org.uk. (Retrieved October 2023). https://www.medicines.org.uk/emc/product/8480/smpc
- Ofloxacin. (n.d.). Medlineplus.Gov. (Retrieved October 2023). https://medlineplus.gov/druginfo/meds/a691005.html
- Tripathi, K. D. (2019). Drugs for Constipation and Diarrhoea, Antiamoebic and Other Antiprotozoal Drugs. In Essentials of Medical Pharmacology (8th ed., pp. 763, 897). essay, Jaypee Brothers Medical Publishers.
- PubChem. (n.d.). Satranidazole. Nih.Gov. (Retrieved October 2023). https://pubchem.ncbi.nlm.nih.gov/compound/41841
- CDSCO. (n.d.). Gov.In. (Retrieved October 2023). https://cdscoonline.gov.in/CDSCO/Drugs
- NCATS Inxight Drugs — SATRANIDAZOLE. (n.d.). Ncats.Io. (Retrieved October 2023). https://drugs.ncats.io/drug/4N7G8A6439
Disclaimer
We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.
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