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Ofloxacin + Satranidazole

Uses of Ofloxacin + Satranidazole

Ofloxacin + Satranidazole is a combination antibiotic and antiprotozoal medicine used for selected mixed gastrointestinal infections.

This combination is commonly used for:

  • Infectious Diarrhoea or Dysentery: May be prescribed when susceptible aerobic bacteria together with anaerobic bacteria or protozoa are suspected.

It should not be presented as routine treatment for urinary, gynaecological, respiratory, wound or postoperative infections without product-specific evidence.

Side effects of Ofloxacin + Satranidazole

  • Nausea

  • Vomiting

  • Abdominal pain

  • Diarrhoea

  • Rash

How Ofloxacin + Satranidazole works

  • Ofloxacin blocks bacterial DNA gyrase and topoisomerase IV, preventing susceptible bacteria from replicating and repairing DNA.
  • Satranidazole is activated in susceptible anaerobic bacteria and protozoa, producing compounds that damage DNA and other essential cell components.
  • Together, these actions cover selected aerobic and anaerobic or protozoal organisms, but they do not guarantee elimination of every mixed infection.

Certified content

Written By

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Dr Nikita LoboMedical Content Reviewer| 9 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi RoshaMedical Content Writer| 10 years

BAMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Ofloxacin + Satranidazole can be taken orally (tablets).

Age and Dose Restrictions

  • This medicine is meant for adults and children who are older than the age where rapid bone growth occurs.

Contraindications

  • This medicine is contraindicated in patients with known allergies to quinolones or nitroimidazoles.

  • It is also contraindicated in growing adolescents, whose bone growth might be affected.

Other Medications to Avoid

  • This combination may interact with several medications, including other antibiotics (such as ciprofloxacin), antacids (like magnesium or aluminum hydroxide), and medications that affect liver enzymes (such as rifampin or phenytoin).

Overdose and Missed Dose

  • An overdose of Ofloxacin + Satranidazole may lead to symptoms such as drowsiness, confusion, dizziness, tremors, or seizures. In such cases, supportive care should be provided including maintaining adequate hydration and monitoring vital signs. Activated charcoal might be considered if ingestion was recent.

  • If a dose is missed, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any symptoms, please consult your doctor.

  • To manage nausea or stomach upset, consider taking the medication with food.

  • If experiencing mild diarrhoea, ensure adequate fluid intake to prevent dehydration.

Use in Driving and Operating Machinery

  • This medication might impair your ability to drive or operate machinery. If you experience symptoms like dizziness or seizures, avoid engaging in tasks that require alertness.

Use in Pregnancy and Lactation

  • Ofloxacin + Satranidazole is contraindicated during pregnancy and lactation. The effects on the developing fetus or nursing infant are potentially harmful.

  • Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Exercise caution when using Ofloxacin + Satranidazole if you have renal (kidney) or hepatic (liver) impairment as dose adjustments may be necessary.

  • Patients with known heart conditions such as arrhythmias should use this medicine with caution due to the risk of QT prolongation.

Special Dietary and Lifestyle Recommendations

  • Maintain adequate hydration especially if gastrointestinal symptoms such as diarrhoea occur.

  • Consider eating smaller, more frequent meals if experiencing nausea or abdominal discomfort.

  • Avoid excessive exposure to sunlight or UV light; wear protective clothing and use sunscreen when outdoors to manage photosensitivity reactions.

  • It is important to observe good personal hygiene to help control infection spread especially in gastrointestinal infections.

Frequently asked questions

No, Ofloxacin + Satranidazole is not a steroid. It is a combination of two antibiotics, belonging to the fluoroquinolone and nitroimidazole classes respectively.

There are no known effects of Ofloxacin + Satranidazole on fertility. However, if you have concerns about fertility or are planning a pregnancy, consult with your doctor before starting this medication.

There is no direct evidence to suggest that Ofloxacin + Satranidazole affects sleep. However, some patients may experience insomnia as a side effect. It is important to report any sleep disturbances to your doctor.

No particular diet restrictions are required during the use of Ofloxacin + Satranidazole. However, it is always good to maintain a balanced and healthy diet while under any kind of medication.

Ofloxacin + Satranidazole is safe for daily use if prescribed by your doctor.

Ofloxacin is rapidly absorbed and reaches its peak serum levels within 1-2 hours after oral administration. However, the time it takes for the medicine to show its effect can vary depending on the severity and type of infection.

The best time to take Ofloxacin + Satranidazole will be prescribed by your doctor.

Ofloxacin + Satranidazole is used to treat diarrhea and dysentery caused by bacterial and protozoal infections. It is effective against gastrointestinal and urinary tract infections and may be used in certain mixed infections as advised by a doctor, rather than broadly treating gynecological, respiratory, and skin infections. This combination works by killing bacteria and parasites, providing relief from symptoms and promoting faster recovery.

Terms & Conditions


List of medicines for Ofloxacin + Satranidazole

Satromax O 300/200 Mg Tablet 10
Satromax O 300/200 Mg Tablet 10
Indchemie Health Specialities Pvt. Ltd.
Pack of 10 Units
₹61.33
MRP ₹76.66
20% OFF
Satrogyl O Dry Syrup 30Ml
Satrogyl O Dry Syrup 30Ml
Alkem Laboratories Ltd.
Pack of 30 ML
₹93.75
MRP ₹117.19
20% OFF
Satrogyl O Dry Syrup 60Ml
Satrogyl O Dry Syrup 60Ml
Alkem Laboratories Ltd.
Pack of 60 ML
₹110.46
MRP ₹128.44
14% OFF
Satrogyl O Tablet 10
Satrogyl O Tablet 10
Alkem Laboratories Ltd.
Pack of 10 Units
₹162.72
MRP ₹203.4
20% OFF

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Telephone:09240250346

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